PRDX5

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PRDX5

Official Full Name peroxiredoxin 5
Background This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms PRDX5; peroxiredoxin 5; peroxiredoxin-5, mitochondrial; ACR1; Alu co repressor 1; antioxidant enzyme B166; AOEB166; B166; liver tissue 2D page spot 71B; MGC117264; MGC142283; MGC142285; peroxisomal antioxidant enzyme; PLP; PMP20; PRDX6; PRXV; SBBI10; thio
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PRDX5-2683H Recombinant Human PRDX5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PRDX5-3781H Recombinant Human PRDX5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Prdx5-5104M Recombinant Mouse Prdx5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human PRDX5-1154H Recombinant Human PRDX5, His tagged E.coli His
    Human PRDX5-181H Recombinant Human Peroxiredoxin 5 E.coli N/A
    Human PRDX5-2878HCL Recombinant Human PRDX5 293 Cell Lysate HEK293 N/A
    Human PRDX5-2879HCL Recombinant Human PRDX5 293 Cell Lysate HEK293 N/A
    Human PRDX5-30762TH Recombinant Human PRDX5 E.coli N/A
    Human PRDX5-324H Recombinant Human PRDX5 Protein, His-tagged E.coli His
    Mouse PRDX5-13326M Recombinant Mouse PRDX5 Protein Mammalian Cell His
    Mouse Prdx5-2545M Recombinant Mouse Prdx5, His tagged E.coli His
    Mouse Prdx5-325M Recombinant Mouse Prdx5 Protein, His-tagged E.coli His
    Rat Prdx5-327R Recombinant Rat Prdx5 Protein, His-tagged E.coli His
    Rat PRDX5-4661R Recombinant Rat PRDX5 Protein Mammalian Cell His
    Zebrafish PRDX5-3010Z Recombinant Zebrafish PRDX5 Mammalian Cell His

    PRDX5 involved in several pathways and played different roles in them. We selected most pathways PRDX5 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Peroxisome NOS2A; PEX11A; PEX13; ACSL3B; ECI2; SCP2; PEX11C; PRDX1; IDH1; ACAA1A

    PRDX5 has several biochemical functions, for example, RNA polymerase III regulatory region DNA binding, antioxidant activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDX5 itself. We selected most functions PRDX5 had, and list some proteins which have the same functions with PRDX5. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase III regulatory region DNA binding PRDX5
    antioxidant activity SELS; PRDX5; APOE; FAM213AA; APOA4; CAT; HP; UBIAD1; FABP1; PRDX2
    cysteine-type endopeptidase inhibitor activity involved in apoptotic process SNCA; PRDX5; TNFSF14; ARRB1; BIRC8; CD27; BIRC3; AVP; TNFAIP8; XIAP
    peroxidase activity GPX7; EPX; MPX; IPCEF1; DUOX2; PXDN; PTGS2; GPX1B; PTGS1; GPX5
    peroxiredoxin activity PARK7; PRDX5; PRDX6
    peroxynitrite reductase activity PRDX5
    protein dimerization activity MESPAA; NEUROD6; ID2A; WWOX; PIP4K2AA; STX2; NPAS4; CREB3; MESPBB; NHLH2
    receptor binding PDGFRB; PARK7; CX3CL1; SMAGP; HILPDA; FGF13B; CAV1; DECR2; NPFFL; C5

    PRDX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDX5.

    IKBKE; PINX1; BABAM1; CCDC90B; ATF2; ICT1; LIN54; SIRT4

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