prdx5
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  • Official Full Name
  • peroxiredoxin 5
  • Background
  • This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms
  • PRDX5; peroxiredoxin 5; peroxiredoxin-5, mitochondrial; ACR1; Alu co repressor 1; antioxidant enzyme B166; AOEB166; B166; liver tissue 2D page spot 71B; MGC117264; MGC142283; MGC142285; peroxisomal antioxidant enzyme; PLP; PMP20; PRDX6; PRXV; SBBI10; thio
Cat.#:PRDX5-324HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX5 Protein, His-tagged
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Cat.#:Prdx5-325MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Prdx5 Protein, His-tagged
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Cat.#:Prdx5-327RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Prdx5 Protein, His-tagged
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Cat.#:PRDX5-1154HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX5, His tagged
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Cat.#:PRDX5-181HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peroxiredoxin 5
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Cat.#:PRDX5-30762THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX5
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Cat.#:PRDX5-13326MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PRDX5 Protein
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Cat.#:Prdx5-2545MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Prdx5, His tagged
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Cat.#:PRDX5-4661RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PRDX5 Protein
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Cat.#:PRDX5-3010ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PRDX5
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Cat.#:PRDX5-2878HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PRDX5 293 Cell Lysate
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Cat.#:PRDX5-2879HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PRDX5 293 Cell Lysate
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Involved Pathway

PRDX5 involved in several pathways and played different roles in them. We selected most pathways PRDX5 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Peroxisome
PEX19; NOS2; ACSL4A; PECR; HAO2; SLC27A2; PEX10; MPV17; PEX14; AMACR

Protein Function

PRDX5 has several biochemical functions, for example, RNA polymerase III regulatory region DNA binding, antioxidant activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDX5 itself. We selected most functions PRDX5 had, and list some proteins which have the same functions with PRDX5. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase III regulatory region DNA binding
Related Protein PRDX5
Function antioxidant activity
Related Protein PRDX6; UBIAD1; SELS; APOA4; CAT; SEPW1; PRDX5; TP53INP1; PRDX2; FABP1
Function cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Related Protein DPEP1; C1QL4L; IGF1RA; PRDX5; RPS6KA1; RPS6KA3; NOL3; ARRB1; MT3; XIAP
Function peroxidase activity
Related Protein GPX1B; PRDX5; MPO; GPX4B; TPO; MPX; PTGS2; PTGS2B; PXDN; GPX4A
Function peroxiredoxin activity
Related Protein PRDX6; PARK7; PRDX5
Function peroxynitrite reductase activity
Related Protein PRDX5
Function protein dimerization activity
Related Protein HER5; MEF2CB; MYO5A; NPAS2; FBXW11A; TCF3B; ARNTL1B; NHLH2; CLOCKA; MESPAA
Function receptor binding
Related Protein CTNND1; TENM2; ANG; DAO; CHRNA10; AGRP2; SRC; CADM2; SELPLG; FGF6B

Interacting Protein

PRDX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDX5.
IKBKE; PINX1; BABAM1; CCDC90B; ATF2; ICT1; LIN54; SIRT4