PTPRJ
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Official Full Name
protein tyrosine phosphatase, receptor type, J
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Overview
CD148, a receptor-like protein tyrosine phosphatase also known as human protein tyrosine phosphatase-eta (HPTP-eta) or density-enhanced protein tyrosine phosphatase-1 (DEP-1), is involved in signal transduction in leucocytes and is thought to contribute t -
Synonyms
PTPRJ; protein tyrosine phosphatase, receptor type, J; receptor-type tyrosine-protein phosphatase eta; CD148; DEP1; HPTPeta; DEP-1; R-PTP-J; HPTP eta; CD148 antigen; density-enhanced phosphatase 1; protein-tyrosine phosphatase eta; human density enhanced phosphatase-1; protein-tyrosine phosphatase receptor type J; susceptibility to colon cancer 1, mouse, homolog of; protein tyrosine phosphatase, receptor type, J polypeptide; SCC1; R-PTP-ETA;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Mouse
- Rat
- Rhesus monkey
- E. coli
- E.coli
- HEK293
- HEK293T
- Insect cells
- Mammalian Cell
- C
- His
- Myc
- DDK
- GST
- hIgG1
- hIgG4
- His|T7
- N/A
- N
- SUMO
- Involved Pathway
- Protein Function
- Interacting Protein
- PTPRJ Related Research Area
PTPRJ involved in several pathways and played different roles in them. We selected most pathways PTPRJ participated on our site, such as Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRJ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adherens junction | WASF3B;TGFBR1B;CTNND1;ACTN3B;PTPRF;SRC;RAC3B;SMAD3;FARP2 |
PTPRJ has several biochemical functions, for example, beta-catenin binding, delta-catenin binding, gamma-catenin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRJ itself. We selected most functions PTPRJ had, and list some proteins which have the same functions with PTPRJ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-catenin binding | PTBP3;TCF7;CTNNBIP1;DACT1;CDH24;CTNNA1;SLC9A3R2;MED12L;MED12 |
| delta-catenin binding | PLEKHA7;DACT3;PLEKHA7A;DACT1;CDH24;DACT2;PTPRJ |
| gamma-catenin binding | PTPRK;CDH2;DSG1A;Fert2;LEF1;TCF7L2;APC;PTPRJ;CDH1 |
| mitogen-activated protein kinase binding | MICALCL;DUSP2;PTPRJ;CDK5RAP3;TPR;MAPKAPK2B;MAPKAPK2A;SIRT1;ACE |
| phosphatase activity | DUSP23A;PTPRJA;DUSP13A;PHOSPHO2;SACM1LA;PTPN4A;PTPN11A;ATP1A1;CTDNEP1 |
| platelet-derived growth factor receptor binding | FIGF;PTPRJ;PDGFC;PDGFAA;PTEN;ITGB3;VEGFA;IL1R1;PDGFRA |
| protein binding | BCL2L10;PPP1R37;VASNA;DHX40;ZW10;VPS25;LACE1;TECPR2;MED20 |
| protein kinase binding | DLG1;MAPK8IP2;KCNA5;DLG1L;SMAD3;GATA4;BCAR1;SV2A;RAB11FIP2 |
| protein tyrosine phosphatase activity | PTPRJ;PTPDC1;PTPRNA;PTPN11A;EVLA;MTMR6;PTPRK;DUSP22B;DUSP13A |
PTPRJ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRJ here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRJ.
MET; CTNND1; PDGFRB; MAPK3; KDR
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