Recombinant Human PTPRJ, GST-tagged
Cat.No. : | PTPRJ-206H |
Product Overview : | Recombinant Human PTPRJ (a.a. 1024-1306) fused with GST-tag at N-terminal, was expressed in an E. coli expression system. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTPRJ-206H |
Description : | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. |
Source : | E. coli |
Molecular Mass : | 58.9 kDa |
Purity : | >95% by SDS-PAGE. |
SpecificActivity : | 268 nmole/min/µg Assay conditions: 20 mM HEPES, pH 7.2, 100 mM NaCl, 2 mM EDTA, 1 mM DTT, 50 mM pNPP and DEP1. Assay was done at 30°C for 10 min, and the reaction was monitored at 405 nm continuously. Specific activity was calculated based on ƐpNP- = 18,000 M-1cm-1 |
Applications : | Useful for the study of enzyme kinetics, regulation, and to dephosphorylate target substrates. |
Formulated in : | 25 mM Tris-HCl, pH 8.0, 75 mM NaCl, 0.05% Tween-20, 50% glycerol, 2 mM EDTA, 1 mM DTT, 10 mM glutathione. |
Stability : | >12 months at –80°C |
OfficialSymbol : | PTPRJ |
Gene Name : | PTPRJ protein tyrosine phosphatase, receptor type, J [ Homo sapiens ] |
Synonyms : | protein tyrosine phosphatase, receptor type, J; DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA; PTPRJ; DEP-1; EC 3.1.3.48; Density-enhanced phosphatase 1;R-PTP-eta; R-PTP-J; HPTP eta;CD148 antigen density-enhanced phosphatase 1; protein-tyrosine phosphatase eta; human density enhanced phosphatase-1 protein-tyrosine phosphatase receptor type J; receptor-type tyrosine-protein phosphatase eta susceptibility to colon cancer 1, mouse, homolog of; protein tyrosine phosphatase, receptor type, J polypeptide |
Gene ID : | 5795 |
mRNA Refseq : | NM_001098503 |
Protein Refseq : | NP_001091973 |
MIM : | 600925 |
UniProt ID : | Q12913 |
Chromosome Location : | 11p11.2 |
Pathway : | Adherens junction; PDGFR-beta signaling pathway; Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
Function : | beta-catenin binding; protein binding; delta-catenin binding; gamma-catenin binding |
Products Types
◆ Recombinant Protein | ||
PTPRJ-2839H | Recombinant Human PTPRJ protein(41-460 aa), C-His-tagged | +Inquiry |
PTPRJ-2837H | Recombinant Human PTPRJ protein(1001-1330 aa), C-His-tagged | +Inquiry |
PTPRJ-2248H | Recombinant Human PTPRJ Protein, Myc/DDK-tagged | +Inquiry |
Ptprj-2247M | Recombinant Mouse Ptprj Protein, Myc/DDK-tagged | +Inquiry |
Ptprj-5247M | Recombinant Mouse Ptprj Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
PTPRJ-2675HCL | Recombinant Human PTPRJ 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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