tdo2
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  • Official Full Name
  • tryptophan 2,3-dioxygenase
  • Background
  • Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.
  • Synonyms
  • TDO2; tryptophan 2,3-dioxygenase; TDO; TPH2; 3-dioxygenase; T23O_HUMAN; TDO 2; TO; TRPO; Tryptamin 2 3 dioxygenase; Tryptamin 2; Tryptophan 2 3 dioxygenase; Tryptophan 2; Tryptophan oxygenase; Tryptophan pyrrolase; Tryptophanase; tryptamin 2,3-dioxygenase
Cat.#:TDO2-2503HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Tryptophan 2,3-Dioxygenase, His-tagged
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Cat.#:TDO2-823HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Tryptophan 2,3-Dioxygenase, T7-tagged
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Cat.#:TDO2-31212THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TDO2
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Cat.#:TDO2-3171HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TDO2, GST-tagged
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Cat.#:TDO2-385HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human TDO2
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Cat.#:TDO2-724HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TDO2 protein, His-tagged
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Cat.#:TDO2-824HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human TDO2, MYC/DDK-tagged
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Cat.#:TDO2-825HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human TDO2, GST-tagged
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Cat.#:TDO2-16601MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TDO2 Protein
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Cat.#:TDO2-5997RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TDO2 Protein
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Cat.#:TDO2-1156HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TDO2 293 Cell Lysate
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Involved Pathway

TDO2 involved in several pathways and played different roles in them. We selected most pathways TDO2 participated on our site, such as Tryptophan metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TDO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Tryptophan metabolism
CCBL1; TDO2B; ACAT2; IL4I1; AOX3L1; OGDHA; ALDH2.1; TPH1; MAOA; HADH
Metabolic pathways
CHSY1; HSD3B1; BCMO1; PLCB3; POLR2GL; GALK1; aLA; DOLK; DHRS4; PTGES3B

Protein Function

TDO2 has several biochemical functions, for example, amino acid binding, heme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TDO2 itself. We selected most functions TDO2 had, and list some proteins which have the same functions with TDO2. You can find most of the proteins on our site.
Function
Related Protein
Function amino acid binding
Related Protein TPH1A; TPH1; TPH2; AARS2; TAT; DDC; OTC; AGXT; GOT2; AARS
Function heme binding
Related Protein CYP46A1.1; CYP4F14; CYP4F12; CYP2C18; HBG2; HBB; CYP2Y3; CYP46A1.4; CYP2A13; CYP27A1
Function metal ion binding
Related Protein BMPR1BA; ENDOU2; PPM1E; ATF7B; ENPP5; ZNF124; ZNF705A; RRM2B; SMAD9; ZFP287
Function oxygen binding
Related Protein CYP2AA8; CYP2C70; CYP2P7; CYP2C39; CYP2C19; CYP2B6; CYP2AA9; CYP17A1; HBZ; CYP2N13
Function protein binding
Related Protein SUB1; PRMT6; CASP14; ARMC1; RPS25; ANXA5; PGBD1; ZBTB7A; DAK; TBC1D15
Function tryptophan 2,3-dioxygenase activity
Related Protein TDO2A; IDO1; IDO2; TDO2; TDO2B

Interacting Protein

TDO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TDO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TDO2.
ASMTL; SDCBP; DPM1; EIF4E; MOB3C; ZFYVE26