ADCY1 Protein


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Official Full Name adenylate cyclase 1 (brain)
Background This gene encodes a form of adenylate cyclase expressed in brain. A similar protein in mouse is involved in pattern formation of the brain.
Synonyms ADCY1; adenylate cyclase 1 (brain); adenylate cyclase type 1; adenyl cyclase; Adenylate cyclase 1; adenylate cyclase type I; ATP pyrophosphate lyase; Brain adenylate cyclase 1; OTTHUMP00000207996; adenylyl cyclase 1; ATP pyrophosphate-lyase 1; 3,5-cyclic AMP synthetase; Ca(2+)/calmodulin-activated adenylyl cyclase; AC1
    • Species :
    • Bovine
    • Human
    • Mouse
    • Source :
    • E.coli
    • E.Coli or Yeast
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADCY1-137H Recombinant Human ADCY1 Mammalian Cell His Inquiry
    Human ADCY1-6841H Recombinant Human ADCY1 protein, His & T7-tagged E.coli His/T7 Inquiry
    Mouse ADCY1-1342M Recombinant Mouse ADCY1 Protein Mammalian Cell His Inquiry
    Mouse Adcy1-3171M Recombinant Mouse Adcy1, His-tagged E.Coli or Yeast His Inquiry
    Mouse Adcy1-6842M Recombinant Mouse Adcy1 protein, His & T7-tagged E.coli His/T7 Inquiry
    Bovine ADCY1-3170B Recombinant Bovine ADCY1, GST-tagged E.Coli or Yeast GST Inquiry

    ADCY1 involved in several pathways and played different roles in them. We selected most pathways ADCY1 participated on our site, such as Activation of GABAB receptors, Activation of NMDA receptor upon glutamate binding and postsynaptic events, Adenylate cyclase activating pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of GABAB receptors GNB3B; ADCY9; KCNJ3; GNGT2A; ADCY6; GNGT2B; GNB3A; KCNJ12; KCNJ2; KCNJ9
    Activation of NMDA receptor upon glutamate binding and postsynaptic events CAMKK1B; DLG4; ADCY3; AKAP9; ADCY1; CREB1B; NETO2; ADCY8; SLC14A2; CREB1
    Adenylate cyclase activating pathway ADCY8; ADCY6; ADCY1; ADCY3; ADCY7; ADCY9
    Adenylate cyclase inhibitory pathway ADCY1; ADCY7; ADCY9; ADCY8; ADCY3; ADCY6
    Adrenergic signaling in cardiomyocytes PPP2CB; PIK3R5; ATP1B1A; CACNG7A; ATP1A4; CAMK2A; TPM2; PIK3R3A; MAPK12; ATP1B2A
    Aldosterone synthesis and secretion PRKACB; PRKCG; SLC14A2; ADCY8; DAGLB; CREB3L4; PRKD1; CREB3L1; PRKCB; ADCY7
    Amoebiasis COL4A1; ARG1; RAB7A; LAMA3; LAMB3; LAMA2; IL12B; TGFB2; SERPINB1A; COL1A2
    Aquaporin-mediated transport GNB5B; GNB3A; AQP10; AQP3B; AQP9B; AQP6; AQP10A; ADCY8; MYO5B; GNB5A

    ADCY1 has several biochemical functions, for example, ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY1 itself. We selected most functions ADCY1 had, and list some proteins which have the same functions with ADCY1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ALPK1; GUCY2C; INSRB; KIF4; ACTA2; AK9; ATAD3A; TLK2; KTI12; SBK1
    adenylate cyclase activity ADCY3; ADCY1; ADCY7; ADCY1A; ADCY1B; Adcy4; GNAS; ADCY9; ADCY8; ADCY2B
    calcium- and calmodulin-responsive adenylate cyclase activity ADCY3; ADCY8; ADCY1; ADCY6
    calmodulin binding CALD1B; MARCKSL1; MYH4; PPP3CB; CAMK1; MYH13; EWSR1; AEBP1; CAMKK1; CAMSAP1L1
    metal ion binding PRKCBB; HINFP; KLF18; GLI1; ZNF74; GALNT11; ZNF821; A3GALT2; KDM4D; DMRTC2

    ADCY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY1.

    Wang, XZ; Maynard, JA; et al. The Bordetella Adenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies. JOURNAL OF BIOLOGICAL CHEMISTRY 290:3576-3591(2015).
    Chae, JJ; Park, YH; et al. Connecting Two Pathways Through Ca2+ Signaling: NLRP3 Inflammasome Activation Induced by a Hypermorphic PLCG2 Mutation. ARTHRITIS & RHEUMATOLOGY 67:563-567(2015).

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