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Recombinant Bovine ADCY1, GST-tagged

Cat.No. : ADCY1-3170B
Product Overview : Adenylate cyclase type 1 (ADCY1)
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Source : E. Coli or Yeast
Species : Bovine
Tag : GST
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 1134
Purity : >90%
Notes : Small volumes of ADCY1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : ADCY1 adenylate cyclase 1 (brain) [ Bos taurus ]
Official Symbol : ADCY1
Synonyms : ADCY1; adenylate cyclase type 1; adenylyl cyclase 1; adenylate cyclase type I; ATP pyrophosphate-lyase 1; ca(2+)/calmodulin-activated adenylyl cyclase
Gene ID : 281601
mRNA Refseq : NM_174229
Protein Refseq : NP_776654
UniProt ID : P19754
Chromosome Location : chromosome: 4
Pathway : Adrenergic signaling in cardiomyocytes, organism-specific biosystem; Adrenergic signaling in cardiomyocytes, conserved biosystem
Function : ATP binding; adenylate cyclase activity; calmodulin binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (13)

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How is Adcy1 protein regulated? 09/25/2022

Adcy1 protein activity is regulated by various mechanisms, including post-translational modifications such as phosphorylation and by interaction with other proteins that can modulate its activity. Adcy1 protein is also subject to regulation by various extracellular signals that activate or inhibit cAMP signaling, including hormones and neurotransmitters.

Are there any ongoing clinical trials involving Adcy1 protein? 06/06/2022

Currently, there are no clinical trials specifically focused on Adcy1 protein. However, some clinical trials are investigating the potential therapeutic effects of drugs that target cAMP signaling, which may indirectly affect Adcy1 activity.

How can Adcy1 protein be targeted for therapeutic use? 10/26/2020

There are several ways to target Adcy1 protein for therapeutic use. One approach is to use small molecule inhibitors to block the activity of Adcy1. Another approach is to use gene therapy to increase or decrease the expression of Adcy1 in specific cells or tissues.

What are the potential therapeutic applications of Adcy1 protein? 09/24/2020

Adcy1 protein has been implicated in a variety of physiological and pathophysiological processes, suggesting that it may have therapeutic potential in a number of conditions. For example, manipulating the activity of Adcy1 could be useful in the treatment of various diseases, such as inflammatory disorders, metabolic disorders, and neurological disorders.

Is Adcy1 protein involved in cancer? 05/16/2020

Dysregulation of cAMP signaling, which is regulated by Adcy1 protein, has been implicated in the development and progression of various types of cancer. For example, decreased Adcy1 expression has been associated with the progression of colorectal cancer. However, more research is needed to fully understand the role of Adcy1 protein in cancer and to evaluate its potential use as a therapeutic target.

Can Adcy1 protein be used to improve cognitive function? 08/13/2019

Adcy1 protein has been shown to play a role in the regulation of synaptic plasticity, which is important for learning and memory. However, more research is needed to fully understand the effects of Adcy1 protein on cognitive function and to determine whether Adcy1-targeted therapies could be useful in treating cognitive disorders such as Alzheimer's disease and other dementias.

Are there any drugs that target Adcy1 protein? 08/28/2018

There are currently no drugs approved for therapeutic use that specifically target Adcy1 protein. However, several drugs that indirectly affect Adcy1 and cAMP signaling, such as beta-blockers and phosphodiesterase inhibitors, are already in clinical use for the treatment of cardiovascular and respiratory disorders.

What are the potential therapeutic applications of Adcy1 protein? 07/06/2018

Adcy1 protein plays a role in the regulation of cyclic AMP (cAMP) signaling, which is involved in many cellular processes. Therapeutic applications of Adcy1 protein may include the treatment of disorders related to abnormal cAMP signaling, such as heart disease, diabetes, and certain types of cancer.

How is Adcy1 protein being studied in research? 12/15/2017

Adcy1 protein is being studied in various research settings to better understand its role in cAMP signaling and cellular processes. This includes studies using cell-based models, animal models, and genetic analyses of patients with disorders related to cAMP signaling. Researchers are also exploring the potential therapeutic effects of Adcy1-targeted drugs on various conditions.

What are the potential side effects of Adcy1-targeted therapies? 11/02/2017

As Adcy1 protein is involved in many cellular processes, targeted therapy for Adcy1 may have off-target effects on other cellular functions. The potential side effects of Adcy1-targeted therapies are not yet fully understood as research in this area is ongoing. However, as with any targeted therapy, potential adverse effects will need to be thoroughly evaluated before clinical use.

What is the structure of Adcy1 protein? 12/10/2016

Adcy1 protein is an enzyme composed of a single protein chain that forms a complex three-dimensional structure. The protein contains multiple domains, including a C1 domain involved in signaling lipids, a catalytic domain that mediates the production of cAMP, and a regulatory domain that modulates its activity in response to various stimuli.

Can Adcy1 protein be used as a drug target? 03/22/2016

Adcy1 protein may be a target for drug development aimed at modulating cAMP signaling. However, the development of Adcy1-targeted drugs is still in the early stages of research and more work is needed to fully understand the role of Adcy1 protein in disease and to identify potential drug targets.

What are some potential advantages and disadvantages of targeting Adcy1 protein therapeutically? 01/17/2016

Potential advantages of targeting Adcy1 protein include the specificity of the therapy, as Adcy1 is not involved in many essential cellular processes, and the potential for personalized medicine, as the activity of Adcy1 can vary depending on the individual and the disease state. However, potential disadvantages include the risk of off-target effects on other cellular processes and the possibility of resistance to therapy developing over time.

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