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Official Full Name aldehyde dehydrogenase 1 family, member A1
Background The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
Synonyms ALDH1A1; aldehyde dehydrogenase 1 family, member A1; ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e; retinal dehydrogenase 1; ALHDII; RALDH 1; ALDH class 1; acetaldehyde dehydrogenase 1; epididymis luminal protein 9; epididymis luminal protein 12; retinaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic; epididymis secretory sperm binding protein Li 53e;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Rabbit
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • T7
    • Met
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALDH1A1-1100H Recombinant Human ALDH1A1 protein, His-tagged E.coli Met/His
    Human ALDH1A1-111H Recombinant Human ALDH1A1 Protein E. coli
    Human ALDH1A1-27035TH Recombinant Human ALDH1A1 protein E.coli N/A
    Human ALDH1A1-27036TH Recombinant Human ALDH1A1, His-tagged E.coli His
    Human ALDH1A1-437H Recombinant Human ALDH1A1 Protein, GST-tagged Wheat Germ GST
    Human ALDH1A1-484H Recombinant Human Aldehyde Dehydrogenase 1 Family, Member A1 E.coli N/A
    Human ALDH1A1-5040H Recombinant Human ALDH1A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ALDH1A1-883H Recombinant Human ALDH1A1, His tagged E.coli His
    Human ALDH1A1-8922HCL Recombinant Human ALDH1A1 293 Cell Lysate HEK293 N/A
    Human ALDH1A1-9550H Recombinant Human ALDH1A1, GST-tagged E.coli GST
    Human CAB11478RH Rabbit Anti-Human Aldehyde Dehydrogenase 1 Family, Member A1 Monoclonal Antibody Rabbit N/A
    Mouse Aldh1a1-1356M Recombinant Mouse Aldh1a1 protein, His & T7-tagged E.coli His/T7
    Mouse ALDH1A1-1518M Recombinant Mouse ALDH1A1 Protein Mammalian Cell His
    Mouse ALDH1A1-1845M Recombinant Mouse ALDH1A1 Protein (2-501 aa), His-tagged Yeast His
    Rat ALDH1A1-614R Recombinant Rat ALDH1A1 Protein Mammalian Cell His
    Chicken ALDH1A1-6146C Recombinant Chicken ALDH1A1 Mammalian Cell His

    aldh1a1 involved in several pathways and played different roles in them. We selected most pathways aldh1a1 participated on our site, such as Retinol metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with aldh1a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Retinol metabolism UGT1A6A; DHRS4; CYP3A65; CYP2C54; ADH2-2; DHRS9; RDH12; CYP3A41A; DGAT1A; DHRS3B
    Metabolic pathways POLR3H; SMPD2A; LYCAT; GAL3ST1; GAA; CHDH; SGMS1; PDXKA; LCT; CBS

    aldh1a1 has several biochemical functions, for example, 3-chloroallyl aldehyde dehydrogenase activity, GTPase activator activity, aldehyde dehydrogenase (NAD) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by aldh1a1 itself. We selected most functions aldh1a1 had, and list some proteins which have the same functions with aldh1a1. You can find most of the proteins on our site.

    Function Related Protein
    3-chloroallyl aldehyde dehydrogenase activity ALDH1A1; ALDH2.1; ALDH9A1; ALDH3B2; ALDH3B1; ALDH3A1; ALDH3A2; ALDH3A2A; ALDH3A2B; Aldh1a7
    GTPase activator activity TIAM2; ARHGEF6; ASAP2A; CDC42EP3; MYO9B; RALGAPA1; GMIP; DAB2IPB; SRGAP3; TBC1D13
    aldehyde dehydrogenase (NAD) activity ALDH3B2; ALDH9A1B; ALDH3A1; ALDH1L2; ALDH5A1; ALDH1L1; ALDH3A2; ALDH6A1; ALDH7A1; ALDH3A2A
    androgen binding Ar; TSPO; ALDH1A1; SHBG
    benzaldehyde dehydrogenase (NAD+) activity ALDH1A1; ALDH3A1; Aldh1a7
    retinal dehydrogenase activity AKR1C6; AKR1B10; ALDH8A1; ALDH1A3; Aldh1a7; ALDH1A1; AKR1C4; AKR1B8; AKR1C3

    aldh1a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aldh1a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of aldh1a1.

    ALDH2; NUPR1; q5nfd5_fratt; ligA; lplJ; POT1

    Liu, Y; Lv, DL; et al. ALDH1A1 expression correlates with clinicopathologic features and poor prognosis of breast cancer patients: a systematic review and meta-analysis. BMC CANCER 14:-(2014).
    Thomas, AG; Henry, JJ; et al. Retinoic acid regulation by CYP26 in vertebrate lens regeneration. DEVELOPMENTAL BIOLOGY 386:291-301(2014).

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