|Official Full Name||aldehyde dehydrogenase 1 family, member A1|
|Background||The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]|
|Synonyms||ALDH1A1; aldehyde dehydrogenase 1 family, member A1; ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e; retinal dehydrogenase 1; ALHDII; RALDH 1; ALDH class 1; acetaldehyde dehydrogenase 1; epididymis luminal protein 9; epididymis luminal protein 12; retinaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic; epididymis secretory sperm binding protein Li 53e;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
aldh1a1 involved in several pathways and played different roles in them. We selected most pathways aldh1a1 participated on our site, such as Retinol metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with aldh1a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Retinol metabolism||UGT1A6A; DHRS4; CYP3A65; CYP2C54; ADH2-2; DHRS9; RDH12; CYP3A41A; DGAT1A; DHRS3B|
|Metabolic pathways||POLR3H; SMPD2A; LYCAT; GAL3ST1; GAA; CHDH; SGMS1; PDXKA; LCT; CBS|
aldh1a1 has several biochemical functions, for example, 3-chloroallyl aldehyde dehydrogenase activity, GTPase activator activity, aldehyde dehydrogenase (NAD) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by aldh1a1 itself. We selected most functions aldh1a1 had, and list some proteins which have the same functions with aldh1a1. You can find most of the proteins on our site.
|3-chloroallyl aldehyde dehydrogenase activity||ALDH1A1; ALDH2.1; ALDH9A1; ALDH3B2; ALDH3B1; ALDH3A1; ALDH3A2; ALDH3A2A; ALDH3A2B; Aldh1a7|
|GTPase activator activity||TIAM2; ARHGEF6; ASAP2A; CDC42EP3; MYO9B; RALGAPA1; GMIP; DAB2IPB; SRGAP3; TBC1D13|
|aldehyde dehydrogenase (NAD) activity||ALDH3B2; ALDH9A1B; ALDH3A1; ALDH1L2; ALDH5A1; ALDH1L1; ALDH3A2; ALDH6A1; ALDH7A1; ALDH3A2A|
|androgen binding||Ar; TSPO; ALDH1A1; SHBG|
|benzaldehyde dehydrogenase (NAD+) activity||ALDH1A1; ALDH3A1; Aldh1a7|
|retinal dehydrogenase activity||AKR1C6; AKR1B10; ALDH8A1; ALDH1A3; Aldh1a7; ALDH1A1; AKR1C4; AKR1B8; AKR1C3|
aldh1a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with aldh1a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of aldh1a1.
ALDH2; NUPR1; q5nfd5_fratt; ligA; lplJ; POT1