Recombinant Mouse ALDH1A1 Protein (2-501 aa), His-tagged
Cat.No. : | ALDH1A1-1845M |
Product Overview : | Recombinant Mouse ALDH1A1 Protein (2-501 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cancer. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
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Description : | In addition to the activity on acetaldehyde and related substrates, is also involved in the oxidation of aldehydes derived from biogenic amines such as epinephrine and norepinephrine, as well as the aldehydes generated via lipid peroxidation. Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid |
Source : | Yeast |
Species : | Mouse |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 56.3 kDa |
Protein length : | 2-501 aa |
AA Sequence : | SSPAQPAVPAPLADLKIQHTKIFIN NEWHNSVSGKKFPVLNPATEEVICH VEEGDKADVDKAVKAARQAFQIGSP WRTMDASERGRLLNKLADLMERDRL LLATMEALNGGKVFANAYLSDLGGC IKALKYCAGWADKIHGQTIPSDGDI FTYTRREPIGVCGQIIPWNFPMLMF IWKIGPALSCGNTVVVKPAEQTPLT ALHLASLIKEAGFPPGVVNIVPGYG PTAGAAISSHMDVDKVAFTGSTQVG KLIKEAAGKSNLKRVTLELGGKSPC IVFADADLDIAVEFAHHGVFYHQGQ CCVAASRIFVEESVYDEFVKRSVER AKKYVLGNPLTPGINQGPQIDKEQH DKILDLIESGKKEGAKLECGGGRWG NKGFFVQPTVFSNVTDEMRIAKEEI FGPVQQIMKFKSVDDVIKRANNTTY GLAAGLFTKDLDKAITVSSALQAGV VWVNCYMMLSAQCPFGGFKMSGNGR ELGEHGLYEYTELKTVAMKISQKNS |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 [ Mus musculus ] |
Official Symbol : | ALDH1A1 |
Synonyms : | ALDH1A1; ALHDII; ALDH-E1; RALDH 1; E1; Ahd2; Ahd-2; Aldh1; Raldh1; Aldh1a2; |
Gene ID : | 11668 |
mRNA Refseq : | NM_013467 |
Protein Refseq : | NP_038495 |
UniProt ID : | P24549 |
Products Types
◆ Recombinant Protein | ||
ALDH1A1-115H | Recombinant Human ALDH1A1 Protein, His-tagged | +Inquiry |
ALDH1A1-0342H | Recombinant Human ALDH1A1 Protein (M1-S501), His tagged | +Inquiry |
ALDH1A1-311H | Recombinant Human ALDH1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALDH1A1-0341H | Recombinant Human ALDH1A1 Protein (M1-S501), Tag Free | +Inquiry |
ALDH1A1-450M | Recombinant Mouse ALDH1A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ALDH1A1-8922HCL | Recombinant Human ALDH1A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionALDH1A1 contributes to cellular detoxification by metabolizing endogenous and exogenous aldehydes, reducing their potential cytotoxic effects.
ALDH1A1's catalytic activity depends on its conserved structural features. Substrate binding involves the aldehyde-binding pocket, and cofactor interaction occurs through the binding of NAD+.
ALDH1A1 contributes to retinoid homeostasis by regulating the levels of active retinoic acid. Dysregulation may lead to diseases associated with vitamin A deficiency or excess.
ALDH1A1 is an aldehyde dehydrogenase enzyme responsible for catalyzing the oxidation of retinaldehyde to retinoic acid, a critical step in the synthesis of retinoids.
ALDH1A1 plays a key role in retinoic acid signaling by generating active retinoic acid. This signaling pathway influences gene expression and cellular differentiation in various tissues.
Customer Reviews (3)
Write a reviewThe attention to detail in quality assurance is commendable. It's a lab favorite for a reason.
Great for assays and experiments. Dependable results make it a lab favorite.
A lab staple! Quality is never compromised, and the shipping is always reliable.
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