Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse ALDH1A1 Protein (2-501 aa), His-tagged

Cat.No. : ALDH1A1-1845M
Product Overview : Recombinant Mouse ALDH1A1 Protein (2-501 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cancer. Protein Description: Full Length of Mature Protein.
  • Specification
  • Gene Information
  • Related Products
Description : In addition to the activity on acetaldehyde and related substrates, is also involved in the oxidation of aldehydes derived from biogenic amines such as epinephrine and norepinephrine, as well as the aldehydes generated via lipid peroxidation. Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid
Source : Yeast
Species : Mouse
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 56.3 kDa
Protein length : 2-501 aa
AA Sequence : SSPAQPAVPAPLADLKIQHTKIFIN NEWHNSVSGKKFPVLNPATEEVICH VEEGDKADVDKAVKAARQAFQIGSP WRTMDASERGRLLNKLADLMERDRL LLATMEALNGGKVFANAYLSDLGGC IKALKYCAGWADKIHGQTIPSDGDI FTYTRREPIGVCGQIIPWNFPMLMF IWKIGPALSCGNTVVVKPAEQTPLT ALHLASLIKEAGFPPGVVNIVPGYG PTAGAAISSHMDVDKVAFTGSTQVG KLIKEAAGKSNLKRVTLELGGKSPC IVFADADLDIAVEFAHHGVFYHQGQ CCVAASRIFVEESVYDEFVKRSVER AKKYVLGNPLTPGINQGPQIDKEQH DKILDLIESGKKEGAKLECGGGRWG NKGFFVQPTVFSNVTDEMRIAKEEI FGPVQQIMKFKSVDDVIKRANNTTY GLAAGLFTKDLDKAITVSSALQAGV VWVNCYMMLSAQCPFGGFKMSGNGR ELGEHGLYEYTELKTVAMKISQKNS
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 [ Mus musculus ]
Official Symbol : ALDH1A1
Synonyms : ALDH1A1; ALHDII; ALDH-E1; RALDH 1; E1; Ahd2; Ahd-2; Aldh1; Raldh1; Aldh1a2;
Gene ID : 11668
mRNA Refseq : NM_013467
Protein Refseq : NP_038495
UniProt ID : P24549

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does ALDH1A1 contribute to cellular detoxification by metabolizing endogenous and exogenous aldehydes? 09/26/2021

ALDH1A1 contributes to cellular detoxification by metabolizing endogenous and exogenous aldehydes, reducing their potential cytotoxic effects.

What are the structural features of ALDH1A1 that are crucial for its catalytic activity, and how do substrate binding and cofactor interaction occur? 08/07/2021

ALDH1A1's catalytic activity depends on its conserved structural features. Substrate binding involves the aldehyde-binding pocket, and cofactor interaction occurs through the binding of NAD+.

How does ALDH1A1 participate in retinoid homeostasis, and what are the consequences of its dysregulation in diseases like vitamin A deficiency or excess? 12/04/2020

ALDH1A1 contributes to retinoid homeostasis by regulating the levels of active retinoic acid. Dysregulation may lead to diseases associated with vitamin A deficiency or excess.

What is the enzymatic function of ALDH1A1, and how does it catalyze the conversion of aldehydes? 08/14/2020

ALDH1A1 is an aldehyde dehydrogenase enzyme responsible for catalyzing the oxidation of retinaldehyde to retinoic acid, a critical step in the synthesis of retinoids.

Can you explain the role of ALDH1A1 in retinoic acid signaling and its impact on cellular processes, including gene expression and differentiation? 05/07/2018

ALDH1A1 plays a key role in retinoic acid signaling by generating active retinoic acid. This signaling pathway influences gene expression and cellular differentiation in various tissues.

Customer Reviews (3)

Write a review
Reviews
08/05/2020

    The attention to detail in quality assurance is commendable. It's a lab favorite for a reason.

    03/12/2019

      Great for assays and experiments. Dependable results make it a lab favorite.

      11/23/2018

        A lab staple! Quality is never compromised, and the shipping is always reliable.

        Ask a Question for All ALDH1A1 Products

        Required fields are marked with *

        My Review for All ALDH1A1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends