• Official Full Name

    annexin A11

  • Background

    This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The en
  • Synonyms

    ANXA11; annexin A11; 56 kDa autoantigen; Annexin XI; Annexin-11; AnnexinA11; AnnexinXI; ANX 11; ANX A11; ANX11; ANX11_HUMAN; ANXA 11; Autoantigen 56 kD; Calcyclin associated annexin 50; Calcyclin-associated annexin 50; CAP 50; CAP-50; CAP50; OTTHUMP00000059806; Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50); A830099O17Rik;
    • Type:
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Cell & Tissue Lysates
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • MYC
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken ANXA11-2118C Recombinant Chicken ANXA11 Mammalian Cell His
    Human ANXA11-3250H Recombinant Human ANXA11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ANXA11-6905H Recombinant Human Annexin A11, His-tagged E.coli His
    Human ANXA11-343H Recombinant Human ANXA11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human ANXA11-629H Recombinant Human ANXA11 protein, GST-tagged Wheat Germ GST
    Human ANXA11-343H-B Recombinant Human ANXA11 Protein Pre-coupled Magnetic Beads HEK293
    Human ANXA11-8836HCL Recombinant Human ANXA11 293 Cell Lysate HEK293 N/A
    Human ANXA11-0423H Recombinant Human ANXA11 Protein (Met1-Asp505), N-His-tagged E.coli N-His
    Human ANXA11-8837HCL Recombinant Human ANXA11 293 Cell Lysate HEK293 N/A
    Human ANXA11-9693H Recombinant Human ANXA11, GST-tagged E.coli GST
    Human ANXA11-26349TH Recombinant Human ANXA11, His-tagged E.coli His
    Human ANXA11-0422H Recombinant Human ANXA11 Protein (Met1-Asp505), His-tagged E.coli His
    Mouse ANXA11-580M-B Recombinant Mouse ANXA11 Protein Pre-coupled Magnetic Beads HEK293
    Mouse ANXA11-580M Recombinant Mouse ANXA11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Anxa11-3493M Recombinant Mouse Anxa11, His-tagged E.Coli or Yeast His
    Mouse ANXA11-1712M Recombinant Mouse ANXA11 Protein Mammalian Cell His
    Mouse Anxa11-606M Recombinant Mouse Anxa11 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    ANXA11 involved in several pathways and played different roles in them. We selected most pathways ANXA11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    ANXA11 has several biochemical functions, for example, MHC class II protein complex binding, S100 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA11 itself. We selected most functions ANXA11 had, and list some proteins which have the same functions with ANXA11. You can find most of the proteins on our site.

    Function Related Protein
    MHC class II protein complex bindingHLA-DOB;PKM;ATP1B1;PKM2;CD74;HLA-DMB;HSPA8;HSP90AA1;HLA-DRA
    S100 protein bindingFGF1;S100A6;AGER;ANXA11;KCNK3;S100A1;ATP2A2;AHNAK;DDX1
    calcium ion bindingJAG1A;MYL12B;CALR;S100A1;MAN1B1;ITGB1BP2;OCM;DLC;CAPN8
    calcium-dependent phospholipid bindingPCLO;SYT3;ANXA8;ANXA1C;ANXA2B;ANXA13;ANXA11;SYT11;ANXA3B
    calcium-dependent protein bindingCALM2;SYT1;S100P;SNAP25;ANXA6;VPS37C;ANXA11;KCNIP3;CALM3
    phosphatidylethanolamine bindingESYT2;NF1;CD300A;ANXA11;PEMT;MFGE8;LC3;PEBP1
    poly(A) RNA bindingNAT10;MRPS5;PRPF40A;NHP2L1;PIGC;CRKL;MRPL21;DDX51;MAP4
    protein bindingRNF13;SYT2;ZNF177;CTU2;XPO5;PDLIM5;RAD18;PHIP;MSTN

    ANXA11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA11 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA11.

    PDCD6; PLSCR1; ENO2; HNRNPH3; folC; proW; q81za2_bacan; ZDHHC17; pi3p; Sept9; Mus81; CDC5L; Racgap1

    • Q&As
    • Reviews

    Q&As (12)

    Ask a question
    Does ANXA11 have any known functions in the nervous system? 11/05/2021

    Yes, ANXA11 has been implicated in various functions within the nervous system. It has been shown to regulate vesicle fusion processes in neuronal synapses, suggesting a role in neurotransmitter release. ANXA11 has also been associated with neuronal differentiation and dendritic branching. Additionally, ANXA11 genetic variants have been linked to neurodegenerative disorders like ALS and FTD, indicating its potential involvement in disease pathogenesis.

    Are there any inhibitors or activators of ANXA11? 08/22/2020

    Currently, there are no specific inhibitors or activators of ANXA11 that have been widely established. However, certain compounds and agents have been reported to affect ANXA11 function indirectly. For example, calcium ionophores and calcium chelators can modulate ANXA11-mediated calcium signaling. Further research is needed to identify specific molecules that can selectively modulate ANXA11 activity.

    Does ANXA11 have any disease associations? 07/08/2020

    ANXA11 has been linked to several diseases and pathological conditions. Certain genetic variations in ANXA11 have been implicated in neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ANXA11 has also been associated with cancer progression and metastasis in certain tumors, highlighting its potential role in oncogenesis.

    Are there any known genetic variations or mutations in the ANXA11 gene? 04/28/2019

    Yes, genetic variations and mutations in the ANXA11 gene have been reported. Some studies have identified single nucleotide polymorphisms (SNPs) in ANXA11 associated with specific diseases, such as Alzheimer's disease and bipolar disorder. Rare variants and mutations in ANXA11 have also been implicated in some cases of amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders.

    Does ANXA11 play a role in autophagy? 02/13/2019

    Yes, ANXA11 has been implicated in the regulation of autophagy, a cellular process involved in the degradation and recycling of cellular components. ANXA11 interacts with key autophagy-related proteins, such as beclin-1, Atg5, and LC3, and may be involved in the formation and maturation of autophagic vesicles.

    Are there any therapeutic implications of ANXA11? 09/24/2018

    The involvement of ANXA11 in various diseases, particularly ALS and FTD, suggests potential therapeutic implications. Understanding the role of ANXA11 in disease pathogenesis may help in the development of targeted therapies. Additionally, because ANXA11 is involved in membrane trafficking and vesicle fusion processes, it could be a potential target for drug delivery systems. However, more research is needed to fully explore the therapeutic potential of ANXA11.

    Can ANXA11 be used as a biomarker for any diseases? 04/29/2018

    While ANXA11 has been associated with certain diseases, its utility as a biomarker is still being explored. Studies have suggested that ANXA11 expression levels may have diagnostic and prognostic value in certain cancer types, including breast, lung, and pancreatic cancer. Further research is needed to determine the specific clinical applicability of ANXA11 as a biomarker.

    Does ANXA11 have any roles in immune response or inflammation? 01/13/2018

    ANXA11 has been implicated in immune response and inflammation processes. It has been shown to regulate the release of pro-inflammatory cytokines, such as interleukin-1 beta (IL-1β), through its involvement in inflammasome signaling pathways. ANXA11 has also been associated with the regulation of immune cell activation and migration. However, further studies are needed to fully elucidate its roles in immune response modulation.

    Is ANXA11 expressed in a tissue-specific manner? 01/12/2018

    ANXA11 is expressed in a variety of tissues and cell types, but its expression levels may vary depending on the tissue or developmental stage. High levels of ANXA11 expression have been observed in the brain, heart, liver, and kidney, among others. It is also expressed in various cancer types, suggesting a potential role in tumorigenesis.

    Is ANXA11 involved in any cellular processes other than autophagy? 01/16/2017

    Yes, ANXA11 is involved in several cellular processes apart from autophagy. It plays a role in membrane trafficking and dynamics, vesicle fusion, calcium signaling, apoptosis regulation, and cellular membrane repair. ANXA11 has also been implicated in cellular processes related to exocytosis, endocytosis, and cellular adhesion.

    Are there any known interacting partners of ANXA11? 07/12/2016

    Yes, ANXA11 interacts with a variety of protein partners in different cellular contexts. Some of its known interacting partners include the SNARE protein SNAP-23, the vesicle-associated protein synaptophysin, the heat shock protein Hsp90, and several components of the endosomal and lysosomal machinery. ANXA11 also interacts with specific miRNAs and RNA-binding proteins, suggesting its involvement in post-transcriptional regulation.

    Are there any known diseases associated with ANXA11? 01/02/2016

    Yes, ANXA11 has been implicated in several diseases. The most well-known association is with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ANXA11 variants have been identified in some familial cases of ALS and FTD, suggesting a genetic susceptibility. ANXA11 has also been linked to cardiovascular diseases, cancer progression, and autoimmune disorders, although more research is needed to fully understand its involvement in these conditions.

    Customer Reviews (5)

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      In addition to its scientific merits, the manufacturer of ANXA11 protein stands out for its outstanding technical support. -


        Whether it be troubleshooting issues, offering experimental guidance, or addressing any concerns, the manufacturer's technical support ensures that researchers have a reliable and knowledgeable resource to rely on. -


          The ANXA11 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials. -


            Its unique properties make ANXA11 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics. -


              The company provides a dedicated team of experts who are readily available to assist researchers throughout their experimental journey. -

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