ANXA11

  • Official Full Name

    annexin A11

  • Overview

    This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The en
  • Synonyms

    ANXA11; annexin A11; 56 kDa autoantigen; Annexin XI; Annexin-11; AnnexinA11; AnnexinXI; ANX 11; ANX A11; ANX11; ANX11_HUMAN; ANXA 11; Autoantigen 56 kD; Calcyclin associated annexin 50; Calcyclin-associated annexin 50; CAP 50; CAP-50; CAP50; OTTHUMP00000059806; Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50); A830099O17Rik;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ANXA11-9693H Recombinant Human ANXA11, GST-tagged E.coli GST 1-180
Human ANXA11-629H Recombinant Human ANXA11 protein, GST-tagged Wheat Germ GST
Human ANXA11-26349TH Recombinant Human ANXA11, His-tagged E.coli His 505 amino acids
Human ANXA11-6905H Recombinant Human Annexin A11, His-tagged E.coli His 1-505aa
Human ANXA11-8836HCL Recombinant Human ANXA11 293 Cell Lysate HEK293 N/A
Human ANXA11-8837HCL Recombinant Human ANXA11 293 Cell Lysate HEK293 N/A
Human ANXA11-3250H Recombinant Human ANXA11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ANXA11-1047HF Recombinant Full Length Human ANXA11 Protein, GST-tagged In Vitro Cell Free System GST 505 amino acids
Human ANXA11-343H Recombinant Human ANXA11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ANXA11-2781H Recombinant Human ANXA11 protein(291-370 aa), C-His-tagged E.coli C-His 291-370 aa
Human ANXA11-1121HFL Recombinant Full Length Human ANXA11 Protein, C-Flag-tagged Mammalian cells Flag
Human ANXA11-343H-B Recombinant Human ANXA11 Protein Pre-coupled Magnetic Beads HEK293
Human ANXA11-0423H Recombinant Human ANXA11 Protein (Met1-Asp505), N-His-tagged E.coli N-His Met1-Asp505
Mouse ANXA11-1712M Recombinant Mouse ANXA11 Protein Mammalian Cell His
Mouse Anxa11-3493M Recombinant Mouse Anxa11, His-tagged E.Coli or Yeast His 503
Mouse ANXA11-580M-B Recombinant Mouse ANXA11 Protein Pre-coupled Magnetic Beads HEK293
Mouse ANXA11-580M Recombinant Mouse ANXA11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Anxa11-606M Recombinant Mouse Anxa11 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Chicken ANXA11-2118C Recombinant Chicken ANXA11 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ANXA11 involved in several pathways and played different roles in them. We selected most pathways ANXA11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ANXA11 has several biochemical functions, for example, MHC class II protein complex binding, S100 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA11 itself. We selected most functions ANXA11 had, and list some proteins which have the same functions with ANXA11. You can find most of the proteins on our site.

Function Related Protein
MHC class II protein complex bindingHLA-DMA;ATP1B1;ANXA11;MS4A1;HLA-DMB;HLA-DRB1;PKM2;HLA-DRA;CD81
S100 protein bindingS100A1;ANXA11;S100A6;EZR;ATP2A2;AGER;KCNK3;AHNAK;FGF1
calcium ion bindingSPOCK2;CABYR;MMP3;EFEMP1;PCDHGA4;BNIP2;NCALD;DST;BMP1A
calcium-dependent phospholipid bindingANXA1;SYT17;SYTL2;SYTL4;PCLO;SYT11;ANXA13;PLA2G4A;ANXA6
calcium-dependent protein bindingMBL1;S100B;PLSCR3;TNNC1;MASP2;MMP13;ANXA2;SLC9A1;PDCD6IP
phosphatidylethanolamine bindingANXA11;PEBP1;LC3;PEMT;NF1;CD300A;ESYT2;MFGE8
poly(A) RNA bindingSRSF12;DHX30;SPTBN1;RBPMS;RBM6;PATL1;RBM12;SF3B2;NXF3
protein bindingCLEC16A;EPHA10;AES;SETD2;LGR6;H2AFX;APBB2;EXOSC2;SMR3B

ANXA11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA11 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA11.

PDCD6; PLSCR1; ENO2; HNRNPH3; folC; proW; q81za2_bacan; ZDHHC17; pi3p; Sept9; Mus81; CDC5L; Racgap1

  • Q&As
  • Reviews

Q&As (12)

Ask a question
Does ANXA11 have any known functions in the nervous system? 11/05/2021

Yes, ANXA11 has been implicated in various functions within the nervous system. It has been shown to regulate vesicle fusion processes in neuronal synapses, suggesting a role in neurotransmitter release. ANXA11 has also been associated with neuronal differentiation and dendritic branching. Additionally, ANXA11 genetic variants have been linked to neurodegenerative disorders like ALS and FTD, indicating its potential involvement in disease pathogenesis.

Are there any inhibitors or activators of ANXA11? 08/22/2020

Currently, there are no specific inhibitors or activators of ANXA11 that have been widely established. However, certain compounds and agents have been reported to affect ANXA11 function indirectly. For example, calcium ionophores and calcium chelators can modulate ANXA11-mediated calcium signaling. Further research is needed to identify specific molecules that can selectively modulate ANXA11 activity.

Does ANXA11 have any disease associations? 07/08/2020

ANXA11 has been linked to several diseases and pathological conditions. Certain genetic variations in ANXA11 have been implicated in neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ANXA11 has also been associated with cancer progression and metastasis in certain tumors, highlighting its potential role in oncogenesis.

Are there any known genetic variations or mutations in the ANXA11 gene? 04/28/2019

Yes, genetic variations and mutations in the ANXA11 gene have been reported. Some studies have identified single nucleotide polymorphisms (SNPs) in ANXA11 associated with specific diseases, such as Alzheimer's disease and bipolar disorder. Rare variants and mutations in ANXA11 have also been implicated in some cases of amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders.

Does ANXA11 play a role in autophagy? 02/13/2019

Yes, ANXA11 has been implicated in the regulation of autophagy, a cellular process involved in the degradation and recycling of cellular components. ANXA11 interacts with key autophagy-related proteins, such as beclin-1, Atg5, and LC3, and may be involved in the formation and maturation of autophagic vesicles.

Are there any therapeutic implications of ANXA11? 09/24/2018

The involvement of ANXA11 in various diseases, particularly ALS and FTD, suggests potential therapeutic implications. Understanding the role of ANXA11 in disease pathogenesis may help in the development of targeted therapies. Additionally, because ANXA11 is involved in membrane trafficking and vesicle fusion processes, it could be a potential target for drug delivery systems. However, more research is needed to fully explore the therapeutic potential of ANXA11.

Can ANXA11 be used as a biomarker for any diseases? 04/29/2018

While ANXA11 has been associated with certain diseases, its utility as a biomarker is still being explored. Studies have suggested that ANXA11 expression levels may have diagnostic and prognostic value in certain cancer types, including breast, lung, and pancreatic cancer. Further research is needed to determine the specific clinical applicability of ANXA11 as a biomarker.

Does ANXA11 have any roles in immune response or inflammation? 01/13/2018

ANXA11 has been implicated in immune response and inflammation processes. It has been shown to regulate the release of pro-inflammatory cytokines, such as interleukin-1 beta (IL-1β), through its involvement in inflammasome signaling pathways. ANXA11 has also been associated with the regulation of immune cell activation and migration. However, further studies are needed to fully elucidate its roles in immune response modulation.

Is ANXA11 expressed in a tissue-specific manner? 01/12/2018

ANXA11 is expressed in a variety of tissues and cell types, but its expression levels may vary depending on the tissue or developmental stage. High levels of ANXA11 expression have been observed in the brain, heart, liver, and kidney, among others. It is also expressed in various cancer types, suggesting a potential role in tumorigenesis.

Is ANXA11 involved in any cellular processes other than autophagy? 01/16/2017

Yes, ANXA11 is involved in several cellular processes apart from autophagy. It plays a role in membrane trafficking and dynamics, vesicle fusion, calcium signaling, apoptosis regulation, and cellular membrane repair. ANXA11 has also been implicated in cellular processes related to exocytosis, endocytosis, and cellular adhesion.

Are there any known interacting partners of ANXA11? 07/12/2016

Yes, ANXA11 interacts with a variety of protein partners in different cellular contexts. Some of its known interacting partners include the SNARE protein SNAP-23, the vesicle-associated protein synaptophysin, the heat shock protein Hsp90, and several components of the endosomal and lysosomal machinery. ANXA11 also interacts with specific miRNAs and RNA-binding proteins, suggesting its involvement in post-transcriptional regulation.

Are there any known diseases associated with ANXA11? 01/02/2016

Yes, ANXA11 has been implicated in several diseases. The most well-known association is with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ANXA11 variants have been identified in some familial cases of ALS and FTD, suggesting a genetic susceptibility. ANXA11 has also been linked to cardiovascular diseases, cancer progression, and autoimmune disorders, although more research is needed to fully understand its involvement in these conditions.

Customer Reviews (5)

Write a review
Reviews
09/08/2021

    In addition to its scientific merits, the manufacturer of ANXA11 protein stands out for its outstanding technical support.

    06/03/2021

      Whether it be troubleshooting issues, offering experimental guidance, or addressing any concerns, the manufacturer's technical support ensures that researchers have a reliable and knowledgeable resource to rely on.

      04/21/2021

        The ANXA11 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

        09/26/2020

          Its unique properties make ANXA11 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.

          08/27/2017

            The company provides a dedicated team of experts who are readily available to assist researchers throughout their experimental journey.

            Ask a Question for All ANXA11 Products

            Required fields are marked with *

            My Review for All ANXA11 Products

            Required fields are marked with *

            logo

            FOLLOW US

            Terms and Conditions        Privacy Policy

            Copyright © 2024 Creative BioMart. All Rights Reserved.

            Contact Us

            • /
            • Service lnquiry:

            Stay Updated on the Latest Bioscience Trends