ARMC10
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Official Full Name
armadillo repeat containing 10 -
Overview
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. -
Synonyms
ARMC10;armadillo repeat containing 10;armadillo repeat-containing protein 10;MGC3195;specific Splicing Variant involved in Hepatocarcinogenesis;SVH;Armadillo repeat containing protein 10;ARMC 10;FLJ37850;PNAS112;Splicing variant involved in hepatocarcinogenesis protein;PNAS-112;PSEC0198
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- HEK293
- E.Coli/Yeast
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- GST
- DDK
- Myc
- His
- Non
- Avi
- Fc
Involved Pathway
ARMC10 involved in several pathways and played different roles in them. We selected most pathways ARMC10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARMC10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ARMC10 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARMC10 itself. We selected most functions ARMC10 had, and list some proteins which have the same functions with ARMC10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ARMC10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARMC10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARMC10.
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References
- Schmidt, A; Langbein, L; et al. Plakophilin 3 - a novel cell-type-specific desmosomal plaque protein. DIFFERENTIATION 64:291-306(1999).
- Paffenholz, R; Franke, WW; et al. Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family. DIFFERENTIATION 61:293-304(1997).
- KUSSEL, P; FRASCH, M; et al. YEAST SRP1, A NUCLEAR-PROTEIN RELATED TO DROSOPHILA AND MOUSE PENDULIN, IS REQUIRED FOR NORMAL MIGRATION, DIVISION, AND INTEGRITY OF NUCLEI DURING MITOSIS. MOLECULAR & GENERAL GENETICS 248:351-363(1995).
