Recombinant Human ARMC10 protein, GST-tagged

• Cat.No.: ARMC10-826H
• Product Overview: Human ARMC10 full-length ORF ( AAH03586.1, 1 a.a. - 308 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 60.2 kDa
• AA Sequence: MGGPRGAGWVAAGLLLGAGACYCIY RLTRGRRRGDRELGIRSSKSAEDLT DGSYDDVLNAEQLQKLLYLLESTED PVIIERALITLGNNAAFSVNQAIIR ELGGIPIVANKINHSNQSIKEKALN ALNNLSVNVENQIKIKIYISQVCED VFSGSLNSAVQLAGLTLLTNMTVTN DHQHMLHSYITDLFQVLLTGNGNTK VQVLKLLLNLSENPAMTEGLLRAQV DSSFLSLYDSHVAKEILLRVLTLFQ NIKNCLKIEGHLAVQPTFTEGSLFF LLHGEECAQKIRALVDHHDAEVKEK VVTIIPKI
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARMC10 armadillo repeat containing 10 [ Homo sapiens ]
• Official Symbol: ARMC10
• Synonyms: ARMC10; armadillo repeat containing 10; armadillo repeat-containing protein 10; MGC3195; specific Splicing Variant involved in Hepatocarcinogenesis; SVH; splicing variant involved in hepatocarcinogenesis protein; specific splicing variant involved in hepatocarcinogenesis; PNAS112; PNAS-112; PSEC0198; FLJ37850
• Gene ID: 83787
• mRNA Refseq: NM_001161009
• Protein Refseq: NP_001154481
• MIM: 611864
• UniProt ID: Q8N2F6