Recombinant Human ARMC10, GST-tagged

• Cat.No.: ARMC10-9867H
• Product Overview: Recombinant Human ARMC10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-262a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ARMC10 armadillo repeat containing 10 [ Homo sapiens ]
• Official Symbol: ARMC10
• Synonyms: ARMC10; armadillo repeat containing 10; armadillo repeat-containing protein 10; MGC3195; specific Splicing Variant involved in Hepatocarcinogenesis; SVH; splicing variant involved in hepatocarcinogenesis protein; specific splicing variant involved in hepatocarcinogenesis; PNAS112; PNAS-112; PSEC0198; FLJ37850
• Gene ID: 83787
• mRNA Refseq: NM_001161009
• Protein Refseq: NP_001154481
• MIM: 611864
• UniProt ID: Q8N2F6
• Chromosome Location: 7q22.1
• Function: binding