Recombinant Human ARMC10, GST-tagged

• Cat.No.: ARMC10-9867H
• Product Overview: Recombinant Human ARMC10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-262a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ARMC10 armadillo repeat containing 10 [ Homo sapiens ]
• Official Symbol: ARMC10
• Synonyms: ARMC10; armadillo repeat containing 10; armadillo repeat-containing protein 10; MGC3195; specific Splicing Variant involved in Hepatocarcinogenesis; SVH; splicing variant involved in hepatocarcinogenesis protein; specific splicing variant involved in hepatocarcinogenesis; PNAS112; PNAS-112; PSEC0198; FLJ37850
• Gene ID: 83787
• mRNA Refseq: NM_001161009
• Protein Refseq: NP_001154481
• MIM: 611864
• UniProt ID: Q8N2F6
• Chromosome Location: 7q22.1
• Function: binding

Reviews

12/14/2022

Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.

06/28/2022

One notable advantage of using the ARMC10 protein is the outstanding technical support provided by its manufacturer.

02/04/2019

the ARMC10 protein has proven to be an invaluable tool in protein electron microscopy (EM) structure analysis.

09/01/2018

The ARMC10 protein is of exceptional quality, making it an ideal choice to meet my experimental needs.

02/17/2018

The ARMC10 protein is an outstanding product that possesses exceptional quality, making it an ideal choice for my experimental needs.

04/24/2017

Their team of experts is readily available to address any issues that may arise, providing solutions to problems and guiding me through the experimental process.

03/27/2017

Its seamless integration makes it possible to explore different research avenues, expanding the scope and impact of my investigations.

02/28/2016

With the manufacturer's excellent technical support and its wide range of applications, the ARMC10 protein has become an indispensable tool, aiding in my research endeavors and driving meaningful scientific discoveries.

Q&As

Are there any known interacting partners of ARMC10 protein?

There is limited information available regarding the interacting partners of ARMC10 protein. Identifying its binding partners through experimental techniques such as co-immunoprecipitation or yeast two-hybrid assays would provide valuable insights into its potential molecular interactions.

Has the functional domain architecture of ARMC10 protein been elucidated?

The functional domain architecture of ARMC10 protein has not been extensively studied. Using bioinformatics tools and domain prediction algorithms can aid in identifying potential functional domains within its amino acid sequence.

Are there any known disease associations or mutations in ARMC10 protein?

Currently, there is limited information available regarding disease associations or mutations in ARMC10 protein. More research is needed to investigate its potential involvement in diseases or any disease-associated mutations.

Does the expression of ARMC10 protein vary in different tissues or developmental stages?

The expression patterns of ARMC10 protein in different tissues or developmental stages have not been extensively characterized. Examining its expression profile using techniques like RNA-seq or immunohistochemistry would provide more insights into its tissue-specific or developmental stage-specific expression.

Can ARMC10 protein modulate cell proliferation or apoptosis?

The impact of ARMC10 protein on cell proliferation or apoptosis has not been elucidated. Experimental studies using cell-based assays, such as proliferation or apoptosis assays, could shed light on its potential role in these processes.

Is ARMC10 protein conserved across different species?

Yes, ARMC10 protein has orthologs or homologs in various species, including mice (Mouse ARMC10) and other vertebrates. Comparative studies can provide insights into its evolutionary conservation and potential functional similarities.

Does ARMC10 protein have any regulatory role in cellular processes?

The regulatory roles of ARMC10 protein in cellular processes are not well-understood. Exploring its potential involvement in signaling pathways, gene expression regulation, or protein-protein interactions could provide insights into its regulatory functions.