Recombinant Full Length Human ARMC10 Protein, GST-tagged

• Cat.No.: ARMC10-1463HF
• Product Overview: Human ARMC10 full-length ORF ( AAH03586.1, 1 a.a. - 308 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 60.2 kDa
• Protein Length: 308 amino acids
• AA Sequence: MGGPRGAGWV AAGLLLGAGA CYCIYRLTRG RRRGDRELGI RSSKSAEDLT DGSYDDVLNA EQLQKLLYLL ESTEDPVIIE RALITLGNNA AFSVNQAIIR ELGGIPIVAN KINHSNQSIK EKALNALNNL SVNVENQIKI KIYISQVCED VFSGSLNSAV QLAGLTLLTN MTVTNDHQHM LHSYITDLFQ VLLTGNGNTK VQVLKLLLNL SENPAMTEGL LRAQVDSSFL SLYDSHVAKE ILLRVLTLFQ NIKNCLKIEG HLAVQPTFTE GSLFFLLHGE ECAQKIRALV DHHDAEVKEK VVTIIPKI
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARMC10 armadillo repeat containing 10 [ Homo sapiens ]
• Official Symbol: ARMC10
• Synonyms: ARMC10; armadillo repeat containing 10; armadillo repeat-containing protein 10; MGC3195; specific Splicing Variant involved in Hepatocarcinogenesis; SVH; splicing variant involved in hepatocarcinogenesis protein; specific splicing variant involved in hepatocarcinogenesis; PNAS112; PNAS-112; PSEC0198; FLJ37850
• Gene ID: 83787
• mRNA Refseq: NM_001161009
• Protein Refseq: NP_001154481
• MIM: 611864
• UniProt ID: Q8N2F6