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Recombinant Human ATG16L1 protein, GST-tagged

Cat.No. : ATG16L1-945H
Product Overview : Human ATG16L1 full-length ORF ( NP_110430.4, 1 a.a. - 523 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 84.7 kDa
AA Sequence : MAQLRIKHQEELTELHKKRGELAQL VIDLNNQMQRKDREMQMNEAKIAEC LQTISDLETECLDLRTKLCDLERAN QTLKDEYDALQITFTALEGKLRKTT EENQELVTRWMAEKAQEANRLNAEN EKDSRRRQARLQKELAEAAKEPLPV EQDDDIEVIVDETSDHTEETSPVRA ISRAATKRLSQPAGGLLDSITNIFG RRSVSSFPVPQDNVDTHPGSGKEVR VPATALCVFDAHDGEVNAVQFSPGS RLLATGGMDRRVKLWEVFGEKCEFK GSLSGSNAGITSIEFDSAGSYLLAA SNDFASRIWTVDDYRLRHTLTGHSG KVLSAKFLLDNARIVSGSHDRTLKL WDLRSKVCIKTVFAGSSCNDIVCTE QCVMSGHFDKKIRFWDIRSESIVRE MELLGKITALDLNPERTELLSCSRD DLLKVIDLRTNAIKQTFSAPGFKCG SDWTRVVFSPDGSYVAAGSAEGSLY IWSVLTGKVEKVLSKQHSSSINAVA WSPSGSHVVSVDKGCKAVLWAQY
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Publication :
The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium (2021)
Gene Name : ATG16L1 ATG16 autophagy related 16-like 1 (S. cerevisiae) [ Homo sapiens ]
Official Symbol : ATG16L1
Synonyms : ATG16L1; ATG16 autophagy related 16-like 1 (S. cerevisiae); APG16 autophagy 16 like (S. cerevisiae) , APG16L, ATG16 autophagy related 16 like (S. cerevisiae) , ATG16L; autophagy-related protein 16-1; ATG16A; FLJ10035; WDR30; APG16L beta; WD repeat domain 30; IBD10; APG16L; ATG16L; FLJ00045; FLJ10828; FLJ22677;
Gene ID : 55054
mRNA Refseq : NM_001190266
Protein Refseq : NP_001177195
MIM : 610767
UniProt ID : Q676U5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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