Recombinant Human ATG16L1 Protein, His-tagged

• Cat.No.: ATG16L1-259H
• Product Overview: Recombinant Human ATG16L1 Protein (Met1-Tyr607) with N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 71.7 kDa
  Accurate Molecular Mass: 70 kDa
• Protein length: Met1-Tyr607
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: ATG16L1 ATG16 autophagy related 16-like 1 (S. cerevisiae) [ Homo sapiens (human) ]
• Official Symbol: ATG16L1
• Synonyms: ATG16L1; ATG16 autophagy related 16-like 1 (S. cerevisiae); APG16 autophagy 16 like (S. cerevisiae), APG16L, ATG16 autophagy related 16 like (S. cerevisiae), ATG16L; autophagy-related protein 16-1; ATG16A; FLJ10035; WDR30; APG16L beta; WD repeat domain 30; IBD10; APG16L; ATG16L; FLJ00045; FLJ10828; FLJ22677
• Gene ID: 55054
• mRNA Refseq: NM_001190266
• Protein Refseq: NP_001177195
• MIM: 610767
• UniProt ID: Q676U5