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Official Full Name ATPase, H+ transporting, lysosomal accessory protein 2
Background This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq, Jul 2008]
Synonyms ATP6AP2; ATPase, H+ transporting, lysosomal accessory protein 2; M8-9; MRXE; XMRE; XPDS; HT028; MRXSH; ELDF10; ATP6IP2; MSTP009; APT6M8-9; ATP6M8-9; renin receptor; N14F; V-ATPase M8.9 subunit; renin/prorenin receptor; ER-localized type I transmembrane adaptor; embryonic liver differentiation factor 10; ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase, H+ transporting, lysosomal interacting protein 2; vacuolar ATP synthase membrane sector-associated protein M8-9; vacuolar proton ATP synthase membrane sector associated protein M8-9; ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9;
    • Species :
    • Chicken
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • Flag
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP6AP2-2184H Recombinant Human ATP6AP2 Protein, His-tagged Yeast His
    Human ATP6AP2-2443H Recombinant Human ATP6AP2 HEK293 N/A
    Human ATP6AP2-2444H Recombinant Human ATP6AP2, His-tagged HEK293 Flag
    Human ATP6AP2-27064TH Native Human ATP6AP2 N/A
    Human ATP6AP2-469H Recombinant Human ATP6AP2 Protein, His-tagged E.coli His
    Human ATP6AP2-8591HCL Recombinant Human ATP6AP2 293 Cell Lysate HEK293 N/A
    Human ATP6AP2-993H Recombinant Human ATP6AP2 protein, GST-tagged Wheat Germ GST
    Rat Atp6ap2-470R Recombinant Rat Atp6ap2 Protein, His-tagged E.coli His
    Rat ATP6AP2-884R Recombinant Rat ATP6AP2 Protein Mammalian Cell His
    Rhesus Macaque ATP6AP2-463R Recombinant Rhesus monkey ATP6AP2 Protein, His-tagged Mammalian Cell His
    Chicken ATP6AP2-2499C Recombinant Chicken ATP6AP2 Mammalian Cell His
    Zebrafish ATP6AP2-12263Z Recombinant Zebrafish ATP6AP2 Mammalian Cell His

    atp6ap2 involved in several pathways and played different roles in them. We selected most pathways atp6ap2 participated on our site, such as ACE Inhibitor Pathway, Metabolism of Angiotensinogen to Angiotensins, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with atp6ap2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ACE Inhibitor Pathway AGTR1; ATP6AP2; ACE; CTSG; AGT; CMA1; AGTR2; CYP11B2
    Metabolism of Angiotensinogen to Angiotensins CPB2; CTSG; CPA3; ACE; CPB1; GZMH; ATP6AP2; CMA1
    Metabolism of proteins SENP1; CEACAM21; HYOU1; PAPPA2; GRP; GALNT5; TIMM23; CST3; GALNT13; INHBAA
    Oxidative phosphorylation NDUFS2; ATP4B; ATPV0E2; NDUFA12; ATP5I; ATP6V0A1A; mt-Atp8; ATP6V1A; ATP6V1G1; ATP5IB
    Peptide hormone metabolism CPB1; CPE; SLC38A8; GZMH; MBOAT4; PCSK2; PCSK1; GPR119; GRP; CMA1
    Renin-angiotensin system CTSA; KLK1B24; ACE2; KLK1B3; CMA1; REN2; KLK1B1; MME; REN; MAS1
    Wnt signaling network WIF1; RYK; CTHRC1; ATP6AP2; IGFBP4; RSPO1

    atp6ap2 has several biochemical functions, for example, aspartic-type endopeptidase activity, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by atp6ap2 itself. We selected most functions atp6ap2 had, and list some proteins which have the same functions with atp6ap2. You can find most of the proteins on our site.

    Function Related Protein
    aspartic-type endopeptidase activity Casp3; ANK2B; DDI1; SPPL3; REN2; REN; PGA5; PGA4; PIP; NOTS
    enzyme binding TRIO; PCBP2; BCL10; LGALS9; BRCA1; NOXA1; TAF10; TSPAN15; BIRC7; SORT1
    protein binding BAD; PSMA7; MAPK6; NFASC; NLRP12; TGFBRAP1; C6; TAF7; KRTAP12-1; NDUFAF1
    receptor activity JMJD6; NR2C2; BTLA; LYVE1; MED14; GPA33; SEMA4D; ITGB1B.1; RAMP3; GRIN1A

    atp6ap2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with atp6ap2 here. Most of them are supplied by our site. Hope this information will be useful for your research of atp6ap2.


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