ATP6AP2

  • Official Full Name

    ATPase, H+ transporting, lysosomal accessory protein 2

  • Overview

    This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq, Jul 2008]
  • Synonyms

    ATP6AP2; ATPase, H+ transporting, lysosomal accessory protein 2; M8-9; MRXE; XMRE; XPDS; HT028; MRXSH; ELDF10; ATP6IP2; MSTP009; APT6M8-9; ATP6M8-9; renin receptor; N14F; V-ATPase M8.9 subunit; renin/prorenin receptor; ER-localized type I transmembrane adaptor; embryonic liver differentiation factor 10; ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase, H+ transporting, lysosomal interacting protein 2; vacuolar ATP synthase membrane sector-associated protein M8-9; vacuolar proton ATP synthase membrane sector associated protein M8-9; ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP6AP2-993H Recombinant Human ATP6AP2 protein, GST-tagged Wheat Germ GST
Human ATP6AP2-2443H Recombinant Human ATP6AP2 HEK293 N/A
Human ATP6AP2-2444H Recombinant Human ATP6AP2, His-tagged HEK293 Flag
Human ATP6AP2-8591HCL Recombinant Human ATP6AP2 293 Cell Lysate HEK293 N/A
Human ATP6AP2-1399H Recombinant Human ATP6AP2 Protein (Asn17-Glu302), His tagged E.coli His Asn17-Glu302
Human ATP6AP2-27064TH Native Human ATP6AP2 N/A
Human ATP6AP2-2572H Recombinant Human ATP6AP2 protein, His-tagged E.coli His 17-350aa
Human ATP6AP2-2573H Recombinant Human ATP6AP2 protein, His-SUMO-tagged E.coli His-SUMO 17-350aa
Human ATP6AP2-02H Recombinant Human ATP6AP2 Protein, His-tagged E.coli His
Human ATP6AP2-469H Recombinant Human ATP6AP2 Protein, His-tagged E.coli His Asn17~Glu302
Human ATP6AP2-1113HF Recombinant Full Length Human ATP6AP2 Protein, GST-tagged In Vitro Cell Free System GST 350 amino acids
Human ATP6AP2-2184H Recombinant Human ATP6AP2 Protein, His-tagged Yeast His
Rat ATP6AP2-884R Recombinant Rat ATP6AP2 Protein Mammalian Cell His
Rat ATP6AP2-540R Recombinant Rat ATP6AP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Atp6ap2-470R Recombinant Rat Atp6ap2 Protein, His-tagged E.coli His Asn18~Glu302
Rat ATP6AP2-540R-B Recombinant Rat ATP6AP2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ATP6AP2-463R Recombinant Rhesus monkey ATP6AP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ATP6AP2-292R-B Recombinant Rhesus Macaque ATP6AP2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ATP6AP2-292R Recombinant Rhesus Macaque ATP6AP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ATP6AP2-12263Z Recombinant Zebrafish ATP6AP2 Mammalian Cell His
Chicken ATP6AP2-2499C Recombinant Chicken ATP6AP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ATP6AP2 involved in several pathways and played different roles in them. We selected most pathways ATP6AP2 participated on our site, such as ACE Inhibitor Pathway, Metabolism of Angiotensinogen to Angiotensins, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6AP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ACE Inhibitor PathwayAGTR1;ACE;CYP11B2;CTSG;CMA1;AGTR2;ATP6AP2;AGT
Metabolism of Angiotensinogen to AngiotensinsCTSG;CMA1;ATP6AP2;GZMH;CPB2;ACE;CPB1;CPA3
Metabolism of proteinsTPP1;ST6GALNAC2;FBXW9;DNAJC24;GALNT5;TUBA1B;PFDN2;GRPEL1;ACE
Oxidative phosphorylationPPA2;COX4I2;ATP6V1F;ATP6V0D1;NDUFS8A;UQCRC2;PPA1;SDHDB;NDUFB1
Peptide hormone metabolismACE;INHBAA;MBOAT4;SLC38A8;PCSK1;CPA3;O3far1;SLC30A8;EXOC8
Renin-angiotensin systemKLK1B11;AGTR1B;MRGPRD;KLK1B3;KLK2;ANPEP;KLK1;MAS1;CPA3
Wnt signaling networkIGFBP4;ATP6AP2;CTHRC1;RSPO1;RYK;WIF1

ATP6AP2 has several biochemical functions, for example, aspartic-type endopeptidase activity, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6AP2 itself. We selected most functions ATP6AP2 had, and list some proteins which have the same functions with ATP6AP2. You can find most of the proteins on our site.

Function Related Protein
aspartic-type endopeptidase activityPGA4;CTSE;NAPSA;ANK2B;Ren1;Casp3;PGA5;BACE1;DDI2
enzyme bindingGRIN1;GBP1;UGT1A2;UGT1A6B;LYN;EGFR;CYP2E1;PIAS3;HIF1A
protein bindingPBK;LYSMD1;CLIP1;NTHL1;ALKBH4;NVL;GINS4;TPD52L3;CAMLG
receptor activityTLR3;Pla2r1;CD200R3;CALCR;ANTXR2;Tnfrsf22;STRA6;V1RA8;CD2

ATP6AP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6AP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6AP2.

USP20; asnB; TMUB1; GOSR1; ESYT2; PDIA3; PON2; WWP2; GOLIM4; LAMTOR5; CHMP2A; ATP6V1G1; SEC22B; FLOT1; ZBTB11; TOP3B; TFRC; ENO1; LGALS1; CLTA

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