Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953


  • Official Full Name

    calpain 3, (p94)

  • Overview

    Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
  • Synonyms

    CAPN3; calpain 3, (p94); p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A; calpain-3; calpain L3; new calpain 1; calpain, large polypeptide L3; calcium-activated neutral proteinase 3; calpain p94, large [catalytic] subunit; muscle-specific calcium-activated neutral protease 3 large subunit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CAPN3-27402TH Recombinant Human CAPN3 Wheat Germ N/A 100 amino acids
Human CAPN3-26374TH Recombinant Human CAPN3, His-tagged E.coli His
Human CAPN3-27209TH Recombinant Human CAPN3 Protein, GST-tagged Wheat Germ GST
Human CAPN3-31H Recombinant Human CAPN3 protein E.coli N/A 156aa
Human CAPN3-7862HCL Recombinant Human CAPN3 293 Cell Lysate HEK293 N/A
Human CAPN3-263H Recombinant Human CAPN3 protein, His-tagged E. coli His 1-156 aa
Human CAPN3-22H Active Recombinant Human CAPN3 Protein, His-tagged E. coli His Ile602-Ala821
Human CAPN3-301255H Recombinant Human CAPN3 protein, GST-tagged E.coli GST Asn488-Met666
Human CAPN3-272H Recombinant Human CAPN3 protein, GST-tagged E. coli GST 1-156 aa
Human CAPN3-1608H Recombinant Human CAPN3 Protein (Ile602-Ala821), His tagged E.coli His Ile602-Ala821
Rat CAPN3-1122R Recombinant Rat CAPN3 Protein Mammalian Cell His
Rat CAPN3-786R-B Recombinant Rat CAPN3 Protein Pre-coupled Magnetic Beads HEK293
Rat CAPN3-786R Recombinant Rat CAPN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CAPN3-359C Recombinant Cynomolgus CAPN3 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CAPN3-107C Recombinant Cynomolgus Monkey CAPN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CAPN3-107C-B Recombinant Cynomolgus Monkey CAPN3 Protein Pre-coupled Magnetic Beads HEK293
Chicken CAPN3-1223C Recombinant Chicken CAPN3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CAPN3 involved in several pathways and played different roles in them. We selected most pathways CAPN3 participated on our site, such as Integrin-mediated cell adhesion, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Integrin-mediated cell adhesionSEPP1;MAPK4;MYLK2;CAPN10;CAPN9;CAPN11;CAPN3;CAPNS1;TNS1

CAPN3 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, catalytic activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPN3 itself. We selected most functions CAPN3 had, and list some proteins which have the same functions with CAPN3. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingCLSTN1;PPP3CA;PCDHGB1;MMP28;CD248A;CALM;MYL12.2;SYT2;CANT1A
calcium-dependent cysteine-type endopeptidase activityCAPN1A;CAPN5;CAPN2;CAPN2A;CAPN13;PEF1;SOLH;CAPNS1B;CAPN3A
cysteine-type peptidase activityCASP5;OTUD7A;CASPB;FAM49BA;CTSB;SENP7B;UFSP2;CASP7;CTSSA
ligase regulator activity
peptidase activityPRSS48;PCSK5;ST14A;HTRA2;CAPN12;F9A;MPND;CAPN8;HE1A
protein complex scaffoldMAGI1;PKP2;MPP7;DISC1;SEPT2;DLG1;MAGI1B;CAV1;AXIN1
signal transducer activityCXCR7B;BST2;GPR62;OLFR181;TAS2R110;GHSRA;OPN4XB;OLFR10;TRIM13
sodium ion bindingSLC24A4A;PDXK;SLC24A4;ATP1A1;SLC24A5;SLC34A2;SLC24A1;SLC24A2;CAPN3
structural constituent of muscleMYH11;MYL1;MYBPC3;TPM4;MYL6;JPH1;DMD;NEXN;COX4I2

CAPN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAPN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAPN3.


  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All CAPN3 Products

Required fields are marked with *

My Review for All CAPN3 Products

Required fields are marked with *



Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends