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Recombinant Human CAPN3 protein

Cat.No. : CAPN3-31H
Product Overview : Recombinant Human CAPN3, was expressed in E. coli.
  • Specification
  • Gene Information
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Description : Phosphatidylethanolamine-binding protein 1 binds ATP, opioids and phosphatidylethanolamine. It has lower affinity for phosphatidylinositol and phosphatidylcholine. It is thought that this protein also function as serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PEBP-1 also inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. It seems to be mediated by a specific receptor.
Source : E.coli
Species : Human
Form : 20mM Tris.Cl, 50mM NaCl, 20% Glycerol, pH9.0.
Molecular Mass : 18.2kDa
Protein length : 156aa
Applications : WB, ELISA, IP, antibody production, protein array
Storage : Store at -80°C and avoid repeated freeze-thaw cycles.
Gene Name : CAPN3 calpain 3, (p94) [ Homo sapiens ]
Official Symbol : CAPN3
Synonyms : CAPN3; LGMD2, LGMD2A; calpain-3; CANP3; nCL 1; p94; calpain L3; LGMD2; nCL-1; CANPL3; LGMD2A; MGC4403; MGC10767; MGC11121; MGC14344;
Gene ID : 825
mRNA Refseq : NM_000070
Protein Refseq : NP_000061
MIM : 114240
UniProt ID : P20807
Chromosome Location : Integrin-mediated cell adhesion, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Pathway : calcium ion binding; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; calcium-dependent cysteine-type endopeptidase activity; calcium-dependent cysteine-type endopeptidase activity; catalytic activity; cysteine-type peptidase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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