Recombinant Full Length Human CAPN3 Protein, N-His-tagged
| Cat.No. : | CAPN3-36HFL |
| Product Overview : | Recombinant Full Length Protein of Human CAPN3, transcript variant 5, fused to His-tag at N-terminus, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | 50mM Tris, pH8.0, 8M Urea. |
| Molecular Mass : | 18.1 kDa |
| AA Sequence : | A DNA sequence encoding the region full length of CAPN3. |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 µg/µL as determined by microplate BCA method. |
| Protein Families : | Druggable Genome, Protease |
| Gene Name : | CAPN3 calpain 3 [ Homo sapiens (human) ] |
| Official Symbol : | CAPN3 |
| Synonyms : | p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A; LGMDD4; LGMDR1 |
| Gene ID : | 825 |
| mRNA Refseq : | NM_173089.2 |
| Protein Refseq : | NP_775112.1 |
| MIM : | 114240 |
| UniProt ID : | P20807 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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