Recombinant Full Length Human CAPN3 Protein, N-His-tagged

• Cat.No.: CAPN3-36HFL
• Product Overview: Recombinant Full Length Protein of Human CAPN3, transcript variant 5, fused to His-tag at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
• Form: 50mM Tris, pH8.0, 8M Urea.
• Molecular Mass: 18.1 kDa
• AA Sequence: A DNA sequence encoding the region full length of CAPN3.
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/µL as determined by microplate BCA method.
• Protein Families: Druggable Genome, Protease
• Full Length: Full L.

Gene Information

• Gene Name: CAPN3 calpain 3 [ Homo sapiens (human) ]
• Official Symbol: CAPN3
• Synonyms: p94; CANP3; LGMD2; nCL-1; CANPL3; LGMD2A; LGMDD4; LGMDR1
• Gene ID: 825
• mRNA Refseq: NM_173089.2
• Protein Refseq: NP_775112.1
• MIM: 114240
• UniProt ID: P20807