CCL18 involved in several pathways and played different roles in them. We selected most pathways CCL18 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Cytokine-cytokine receptor interaction |
GHR; GM13306; TNFRSF13B; Kitl; IFNL3; CXCL16; CCL13; TNFRSF10A; TNFRSF6B; Pdgfa&Pdgfb |
| Chemokine signaling pathway |
PLCB2; CCL11; MAPK3; CCR1; CXCL10; CX3CR1; Adcy4; CCR7; PRKCB; Cxcl15 |
CCL18 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL18 itself. We selected most functions CCL18 had, and list some proteins which have the same functions with CCL18. You can find most of the proteins on our site.
| Function |
Related Protein |
| CCR chemokine receptor binding |
CCL20B; CCL1; CCL8; CCL21; CCL16; CCL33.3; CCL34B.1; CCL19A.2; CCL19A.1; CCL35.1 |
| chemokine activity |
CCL13; Ccl9; CCL19B; CCL7; CXCL8B.3; XCL1; CCL35.2; CCL8; CCL5; CCL25B |
| protein binding |
NIPA2; JAK3; RFESD; TNFSF12; PTCH1; NUDT10; NDUFB10; KRT14; RXRA; CLPX |
CCL18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL18 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL18.
PITPNM3; TP53; EEF1A1; TLE1; UNC119; CRMP1; C14orf1
Xu, Y; Zhang, L; et al. CC Chemokine Ligand 18 and IGF-Binding Protein 6 as Potential Serum Biomarkers for Prostate Cancer. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 233:25-31(2014).
Suga, H; Sugaya, M; et al. The Role of IL-32 in Cutaneous T-Cell Lymphoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY 134:1428-1435(2014).
