Recombinant Human CCL18 protein
| Cat.No. : | CCL18-200H |
| Product Overview : | Recombinant Human CCL18 was expressed in E. coli. |
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- Gene Information
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| Description : | CCL18, also designated dendritic cell (DC)3-derived CC chemokine 1, pulmonary and activation-regulated chemokine, alternative macrophage activation-associated CC chemokine 1, and MIP-4, is a human chemokine structurally related to CCL3. CCL18 was shown to be expressed in germinal centers of tonsils by dendritic cells and to attract mainly naive T cells, CD38 mantle zone B lymphocytes and DC. The production of CCL18 by APC is enhanced by Th2 cytokines like IL-4 and IL-13 and suppressed by IFN-gamma. |
| Source : | E. coli |
| Species : | Human |
| Form : | Recombinant CC18 was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5. |
| Molecular Mass : | 8.0 kDa |
| Endotoxin : | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Purity : | 95% |
| Applications : | Cell Assay |
| Storage : | The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade- 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Reconstitution : | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Gene Name : | CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) [ Homo sapiens ] |
| Official Symbol : | CCL18 |
| Synonyms : | CCL18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated); SCYA18, small inducible cytokine subfamily A (Cys Cys), member 18, pulmonary and activation regulated; C-C motif chemokine 18; AMAC 1; CKb7; DC CK1; DCCK1; MIP 4; PARC; CC chemokine PARC; CC chemokine ligand 18; chemokine (C-C), dendritic; dendritic cell chemokine 1; small inducible cytokine A18; small-inducible cytokine A18; macrophage inflammatory protein 4; pulmonary and activation-regulated chemokine; alternative macrophage activation-associated CC chemokine 1; small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated; AMAC1; MIP-4; AMAC-1; DC-CK1; SCYA18; |
| Gene ID : | 6362 |
| mRNA Refseq : | NM_002988 |
| Protein Refseq : | NP_002979 |
| MIM : | 603757 |
| UniProt ID : | P55774 |
| Chromosome Location : | 17q11.2 |
| Pathway : | Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
| Function : | chemokine activity; protein binding; |
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| ◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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