CLCF1
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Official Full Name
cardiotrophin-like cytokine factor 1 -
Overview
Cardiotrophin-like cytokine factor 1 (CLCF1), also known as Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene. -
Synonyms
BSF-3;BSF3;CISS2;CLC;NNT-1;NNT1;NR6;B-cell stimulating factor 3;B-cell stimulatory factor 3;B-cell-stimulating factor 3;CRLF1 associated cytokine-like factor 1;neurotrophin-1/B-cell stimulating factor-3;novel neurotrophin-1
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cells
- Human Cells
- Human
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Fc
- Avi
- DDK
- Myc
Involved Pathway
CLCF1 involved in several pathways and played different roles in them. We selected most pathways CLCF1 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLCF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | TGFB3,GDF5,CCL23,TGFBR1A,IL17RB,IL-8,IL2RA,TNFRSF17,CCR6A,CSH |
Protein Function
CLCF1 has several biochemical functions, for example, ciliary neurotrophic factor receptor binding,contributes_to ciliary neurotrophic factor receptor binding,contributes_to cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLCF1 itself. We selected most functions CLCF1 had, and list some proteins which have the same functions with CLCF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | GM13288,Ccl12,FAM3D,IFNA1,Ifnz,GM13289,TNFSF15,IL8L2,INHBA,TNFSF10 |
| ciliary neurotrophic factor receptor binding | Ctf2,LIFR,CNTF,IL6ST |
| protein binding | MRPL44,ZKSCAN3,TGIF1,C4BP,STXBP1,MGARP,ELMO3,UXT,CLN6,TSPAN12 |
| receptor binding | GFRA3,CCL15,HAO1,RAB8B,UFD1L,ICOSLG,EHHADH,Ar,FLT3LG,NPFFL |
| contributes_to ciliary neurotrophic factor receptor binding | CRLF1 |
| growth factor activity | ENDOU,EGF,OGN,THBS4,AGT,TGFA,CECR1A,TGFB1,PTN,CSF2 |
| protein heterodimerization activity | PDGFB,SUPT5H,HEYL,CAPN2,PDSS1,H2AFZ,SMC3,SLC51A,MCL1B,H2AFB1 |
| contributes_to cytokine activity | CRLF1,IL12B,IL12A |
Interacting Protein
CLCF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLCF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLCF1.
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References
- Dernyanets, S; Huber, K; et al. Vascular effects of glycoprotein130 ligands - Part II: Biomarkers and therapeutic targets. VASCULAR PHARMACOLOGY 57:29-40(2012).
- Silver, JS; Hunter, CA; et al. gp130 at the nexus of inflammation, autoimmunity, and cancer. JOURNAL OF LEUKOCYTE BIOLOGY 88:1145-1156(2010).
