clcf1
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  • Official Full Name
  • cardiotrophin-like cytokine factor 1
  • Background
  • Cardiotrophin-like cytokine factor 1 (CLCF1), also known as Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene.
  • Synonyms
  • BSF-3; BSF3; CISS2; CLC; NNT-1; NNT1; NR6; B-cell stimulating factor 3; B-cell stimulatory factor 3; B-cell-stimulating factor 3; CRLF1 associated cytokine-like factor 1; neurotrophin-1/B-cell stimulating factor-3; novel neurotrophin-1
Cat.#:CLCF1-1413HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CLCF1 Protein, GST-tagged
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Cat.#:CLCF1-3242HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CLCF1 Protein, MYC/DDK-tagged
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Cat.#:CLCF1-618HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLCF1 Protein, His-tagged
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Cat.#:Clcf1-619MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Clcf1 Protein, His-tagged
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Cat.#:CLCF1-953HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Cardiotrophin-like Cytokine Factor 1
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Cat.#:CLCF1-11277HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLCF1, His-tagged
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Cat.#:CLCF1-29299THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLCF1, His-tagged
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Cat.#:CLCF1-30449THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLCF1
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Cat.#:CLCF1-351HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CLCF1, Fc-tagged
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Cat.#:CLCF1-3626HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLCF1, His-tagged
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Cat.#:CRLF1&CLCF1-1036HTag:
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human CRLF1&CLCF1
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Cat.#:CLCF1-3511MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CLCF1 Protein
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Cat.#:CLCF1-001HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CLCF1 cell lysate
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Involved Pathway

CLCF1 involved in several pathways and played different roles in them. We selected most pathways CLCF1 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLCF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CD40LG; TNFRSF13B; GM13305; Il23a; Il12b; M17; CXCL6; IFNA2; Ifna11; IL-8; Pdgfa&Pdgfb

Protein Function

CLCF1 has several biochemical functions, for example, ciliary neurotrophic factor receptor binding, contributes_to ciliary neurotrophic factor receptor binding, contributes_to cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLCF1 itself. We selected most functions CLCF1 had, and list some proteins which have the same functions with CLCF1. You can find most of the proteins on our site.
Function
Related Protein
Function ciliary neurotrophic factor receptor binding
Related Protein Ctf2; LIFR; CNTF; IL6ST; CLCF1
Function contributes_to ciliary neurotrophic factor receptor binding
Related Protein CLCF1; CRLF1
Function contributes_to cytokine activity
Related Protein CRLF1; CLCF1; IL12A; IL12B
Function cytokine activity
Related Protein IL25; IL17A/F1; CXCL9; TNFSF10; IL18; Ifna11; GPI1; IL1A; Ccl9; TGFB1A
Function growth factor activity
Related Protein IL3; PTN; THBS4; FGF3; GDF10; GDF1; GSDF; F2; TGFB3; IGF3
Function protein binding
Related Protein OCRL; TEK; AMPH; UBL4B; FAM9A; C21orf56; L3MBTL3; HOOK3; OSTF1; RNF6
Function protein heterodimerization activity
Related Protein KCNH5; SMAD3; DR1; HIST1H4L; NR2C2; TAL1; HEXB; SYT10; BAXB; HIST1H2BL
Function receptor binding
Related Protein PTPRD; IDE; NUDT7; MSN; SEMA4D; LAMA1; NOS2; CADM2A; SSTR3; PICK1

Interacting Protein

CLCF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLCF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLCF1.
ESR2

CLCF1 Related Articles

Dernyanets, S; Huber, K; et al. Vascular effects of glycoprotein130 ligands - Part II: Biomarkers and therapeutic targets. VASCULAR PHARMACOLOGY 57:29-40(2012).
Silver, JS; Hunter, CA; et al. gp130 at the nexus of inflammation, autoimmunity, and cancer. JOURNAL OF LEUKOCYTE BIOLOGY 88:1145-1156(2010).

CLCF1 Related Gene Family

IL