Epha4

  • Official Full Name

    EPH receptor A4

  • Background

    This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically h
  • Synonyms

    EPHA4; EPH receptor A4; EphA4 , TYRO1; ephrin type-A receptor 4; Hek8; EK8; EPH-like kinase 8; TYRO1 protein tyrosine kinase; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; receptor protein-tyrosine kinase HEK8; SEK; TYRO1;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • DDK|His
    • Fc
    • Fc|His
    • GST
    • GST|His
    • His
    • His (Fc)
    • Avi
    • His|GST
    • N/A
    • No tag
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken EPHA4-6345C Recombinant Chicken EPHA4 Mammalian Cell His
    Cynomolgus Monkey EPHA4-1192CCL Recombinant Cynomolgus EPHA4 cell lysate Human Cell N/A
    Human EPHA4-001HCL Recombinant Human EPHA4 cell lysate Insect Cell N/A
    Human EPHA4-302H Recombinant Human EPH Receptor A4, GST-tagged, Active Sf9 Insect Cell GST
    Human EPHA411531H Recombinant Human EPHA4 (606-896) Protein
    Human EPHA4-26439TH Recombinant Human EPHA4 N/A
    Human EPHA4-3204H Recombinant Human EPHA4, His tagged Human Cell His
    Human EPHA4-1933HCL Recombinant Human EPHA4 cell lysate Human Cell N/A
    Human EPHA4-3636H Recombinant Human EPHA4 protein, GST-tagged E.coli GST
    Human EPHA4-366H Recombinant Human EPHA4 Protein, DDK/His-tagged HEK293 DDK/His
    Human EPHA4-3385H Recombinant Human EPHA4 Protein, GST/His-tagged Insect Cell GST/His
    Human EPHA4-942H Recombinant Human EPHA4, Fc-His tagged Human Cell Fc/His
    Human EPHA4-3087H Recombinant Human EPHA4 protein, His-tagged E.coli His
    Human EPHA4-1137H Recombinant Human EPHA4 protein, His & GST-tagged E.coli His/GST
    Human EPHA4-0977H Recombinant Human EPHA4 Protein (E252-V986), Tag Free Insect Cell No tag
    Human EPHA4-7315H Recombinant Human EPHA4, His & GST tagged Insect Cell His/GST
    Human EPHA4-67H Recombinant Human EPHA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human EPHA4-3384H Recombinant Human EPHA4 Protein, GST-tagged Insect Cell GST
    Human EphA4-1402H Recombinant Human EphA4 protein, His-tagged HEK293 His
    Human EPHA4-550H Active Recombinant Human EPHA4 Protein, Fc Chimera Mammalian cells Fc
    Human EPHA4-3386H Recombinant Human EPHA4 Protein, GST-tagged Wheat Germ GST
    Human EPHA4-0978H Recombinant Human EPHA4 Protein (E252-V986), GST tagged Insect Cell GST
    Human EPHA4-67H-B Recombinant Human EPHA4 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Epha4-10543M-B Recombinant Mouse Epha4 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Epha4-912M Recombinant Mouse Epha4, Fc tagged Human Cell Fc
    Mouse Epha4-10543M Recombinant Mouse Epha4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Epha4-1724M Recombinant Mouse Eph Receptor A4 Mammalian cells N/A
    Mouse EPHA4-2136MCL Recombinant Mouse EPHA4 cell lysate Human Cell N/A
    Mouse Epha4-913M Recombinant Mouse Epha4 protein, His-tagged HEK293 His
    Rat Epha4-7439R Recombinant Rat Epha4, Fc tagged Human Cell Fc
    Rat Epha4-7440R Recombinant Rat Epha4, His tagged Human Cell His
    Rat EPHA4-1446RCL Recombinant Rat EPHA4 cell lysate Human Cell N/A
    Rhesus Macaque EPHA4-1309R-B Recombinant Rhesus Macaque EPHA4 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque EPHA4-1176R Active Recombinant Rhesus EPHA4 Protein, His-tagged HEK293 His
    Rhesus Macaque EPHA4-1484R Recombinant Rhesus monkey EPHA4 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque EPHA4-1175R Active Recombinant Rhesus EPHA4 Protein, Fc-tagged HEK293 Fc
    Rhesus Macaque EPHA4-1309R Recombinant Rhesus Macaque EPHA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Epha4 Related Articles

    Epha4 involved in several pathways and played different roles in them. We selected most pathways Epha4 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with Epha4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidanceNRAS;EPHA4;EPHB6;NTNG1;PLXNB2;HFE2;SEMA3AB;UNC5D;CSF2

    Epha4 has several biochemical functions, for example, ATP binding, DH domain binding, GPI-linked ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Epha4 itself. We selected most functions Epha4 had, and list some proteins which have the same functions with Epha4. You can find most of the proteins on our site.

    Function Related Protein
    ATP bindingCDK14;ABCC3;CDC34A;TOP2B;PRKACA;EPHB4;SMC2;AKT3;NEK11
    DH domain binding
    GPI-linked ephrin receptor activityEPHA5;EPHA7;EPHA4;EPHA3;EPHA8;EK1
    PH domain bindingEPB41L2;INPP5A;EPHA4
    ephrin receptor bindingNTRK1;EFNA2;PTPN1;CRK;EFNB3B;EFNB2;EFNA5B;CHN1;EFNA1B
    identical protein bindingP2RX6;TPD52L1;CSNK2B;CEP57L1;TYSND1;UHRF1;VIM;PLIN5;SH3GL1
    protein bindingHSCB;UBE2L6;ZFYVE21;ATG13;RAC1;CASP14;TEX14;GPI1;STAC
    protein kinase activityGC3;AKT1;AKT2L;EPHB4B;IRAK1;RPS6KAL;EPHA1;PAK2B;BMPR1AB
    transmembrane-ephrin receptor activityEPHA5;EPHA4;EFNA3;EPHB2;EPHA10;EPHB1;EFNB3;EPHA1;EFNA4

    Epha4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Epha4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Epha4.

    IKBKG; HSP90AB1

    Shi, M; Movius, J; et al. Cerebrospinal Fluid Peptides as Potential Parkinson Disease Biomarkers: A Staged Pipeline for Discovery and Validation. MOLECULAR & CELLULAR PROTEOMICS 14:544-555(2015).
    Kempf, A; Montani, L; et al. Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration. EUROPEAN JOURNAL OF NEUROSCIENCE 38:3567-3579(2013).
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