Epha4
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Official Full Name
EPH receptor A4
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Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically h -
Synonyms
EPHA4; EPH receptor A4; EphA4 , TYRO1; ephrin type-A receptor 4; Hek8; EK8; EPH-like kinase 8; TYRO1 protein tyrosine kinase; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; receptor protein-tyrosine kinase HEK8; SEK; TYRO1;
- Involved Pathway
- Protein Function
- Interacting Protein
- Epha4 Related Articles
Epha4 involved in several pathways and played different roles in them. We selected most pathways Epha4 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with Epha4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | NRAS;EPHA4;EPHB6;NTNG1;PLXNB2;HFE2;SEMA3AB;UNC5D;CSF2 |
Epha4 has several biochemical functions, for example, ATP binding, DH domain binding, GPI-linked ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Epha4 itself. We selected most functions Epha4 had, and list some proteins which have the same functions with Epha4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | CDK14;ABCC3;CDC34A;TOP2B;PRKACA;EPHB4;SMC2;AKT3;NEK11 |
| DH domain binding | |
| GPI-linked ephrin receptor activity | EPHA5;EPHA7;EPHA4;EPHA3;EPHA8;EK1 |
| PH domain binding | EPB41L2;INPP5A;EPHA4 |
| ephrin receptor binding | NTRK1;EFNA2;PTPN1;CRK;EFNB3B;EFNB2;EFNA5B;CHN1;EFNA1B |
| identical protein binding | P2RX6;TPD52L1;CSNK2B;CEP57L1;TYSND1;UHRF1;VIM;PLIN5;SH3GL1 |
| protein binding | HSCB;UBE2L6;ZFYVE21;ATG13;RAC1;CASP14;TEX14;GPI1;STAC |
| protein kinase activity | GC3;AKT1;AKT2L;EPHB4B;IRAK1;RPS6KAL;EPHA1;PAK2B;BMPR1AB |
| transmembrane-ephrin receptor activity | EPHA5;EPHA4;EFNA3;EPHB2;EPHA10;EPHB1;EFNB3;EPHA1;EFNA4 |
Epha4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Epha4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Epha4.
IKBKG; HSP90AB1
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