Recombinant Human EPHA4 Protein, GST-tagged

• Cat.No.: EPHA4-3386H
• Product Overview: Human EPHA4 full-length ORF ( NP_004429.1, 1 a.a. - 986 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 136.3 kDa
• AA Sequence: MAGIFYFALFSCLFGICDAVTGSRV YPANEVTLLDSRSVQGELGWIASPL EGGWEEVSIMDEKNTPIRTYQVCNV MEPSQNNWLRTDWITREGAQRVYIE IKFTLRDCNSLPGVMGTCKETFNLY YYESDNDKERFIRENQFVKIDTIAA DESFTQVDIGDRIMKLNTEIRDVGP LSKKGFYLAFQDVGACIALVSVRVF YKKCPLTVRNLAQFPDTITGADTSS LVEVRGSCVNNSEEKDVPKMYCGAD GEWLVPIGNCLCNAGHEERSGECQA CKIGYYKALSTDATCAKCPPHSYSV WEGATSCTCDRGFFRADNDAASMPC TRPPSAPLNLISNVNETSVNLEWSS PQNTGGRQDISYNVVCKKCGAGDPS KCRPCGSGVHYTPQQNGLKTTKVSI TDLLAHTNYTFEIWAVNGVSKYNPN PDQSVSVTVTTNQAAPSSIALVQAK EVTRYSVALAWLEPDRPNGVILEYE VKYYEKDQNERSYRIVRTAARNTDI KGLNPLTSYVFHVRARTAAGYGDFS EPLEVTTNTVPSRIIGDGANSTVLL VSVSGSVVLVVILIAAFVISRRRSK YSKAKQEADEEKHLNQGVRTYVDPF TYEDPNQAVREFAKEIDASCIKIEK VIGVGEFGEVCSGRLKVPGKREICV AIKTLKAGYTDKQRRDFLSEASIMG QFDHPNIIHLEGVVTKCKPVMIITE YMENGSLDAFLRKNDGRFTVIQLVG MLRGIGSGMKYLSDMSYVHRDLAAR NILVNSNLVCKVSDFGMSRVLEDDP EAAYTTRGGKIPIRWTAPEAIAYRK FTSASDVWSYGIVMWEVMSYGERPY WDMSNQDVIKAIEEGYRLPPPMDCP IALHQLMLDCWQKERSDRPKFGQIV NMLDKLIRNPNSLKRTGTESSRPNT ALLDPSSPEFSAVVSVGDWLQAIKM DRYKDNFTAAGYTTLEAVVHVNQED LARIGITAITHQNKILSSVQAMRTQ MQQMHGRMVPV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EPHA4 EPH receptor A4 [ Homo sapiens ]
• Official Symbol: EPHA4
• Synonyms: EPHA4; EPH receptor A4; EphA4 , TYRO1; ephrin type-A receptor 4; Hek8; EK8; EPH-like kinase 8; TYRO1 protein tyrosine kinase; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; receptor protein-tyrosine kinase HEK8; SEK; HEK8; TYRO1
• Gene ID: 2043
• mRNA Refseq: NM_004438
• Protein Refseq: NP_004429
• MIM: 602188
• UniProt ID: P54764