fgf15

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fgf15

Official Full Name fibroblast growth factor 15
Background Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
Synonyms FGF19
    • Species :
    • Mouse
    • Source :
    • E.coli
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • SUMO
    • Myc/DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Fgf15-1213M Recombinant Mouse Fgf15 Protein, His-SUMO-tagged E.coli His/SUMO
    Mouse Fgf15-2996M Recombinant Mouse Fgf15 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Fgf15-499M Recombinant Mouse Fgf15, His-tagged E.coli His
    Mouse FGF15-5843M Recombinant Mouse FGF15 Protein Mammalian Cell His

    fgf15 involved in several pathways and played different roles in them. We selected most pathways fgf15 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with fgf15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway RASGRF2; FGF2; MAP4K4; HSP70L; MAP2K5; RPS6KA1; TGFB2; CACNB4A; PPM1NB; PRKACBB
    Ras signaling pathway CDC42; Pdgfa&Pdgfb; PLCG1; RALBP1; GNG7; VEGFA; SHC3; MET; GRB2; MAPK8
    Rap signaling pathway ARAP3; FGFR4; PRKCZ; FGF1; PLCB1; LAT; MAGI2; SKAP1; MAPK13; Kitl
    PIK-Akt signaling pathway PDPK1; Pdgfa&Pdgfb; IL7; PRKAA2; COL4A1; PKN2; ANGPT1; IGF1R; ITGB5; RPTOR
    Regulation of actin cytoskeleton PIP5K1C; PAK2A; PIK3CB; PDGFD; HRAS; BDKRB2; APC; ITGB6; MYL2; PIK3R3
    Pathways in cancer WNT11; FGF7; MAPK8; RXRA; GNAI3; CYCS; PIK3R2; TGFA; RXRG; BIRC5
    Melanoma MDM2; CCND1; FGF14; FGF8; MAPK1; FGF1; PDGFRA; FGF10; IGF1R; NRAS

    fgf15 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fgf15 itself. We selected most functions fgf15 had, and list some proteins which have the same functions with fgf15. You can find most of the proteins on our site.

    Function Related Protein
    fibroblast growth factor receptor binding FGF6; FGF4; FRS2; FGF18A; FGF18B; FGF8; FGF8A; FGF20B; FGF20A; Fgf15
    growth factor activity FGF12A; BMP7B; TGFA; AMELX; BMP5; FGF8A; GDF1; GDF6B; IL5; FGF20B
    protein binding KPNA6; RSPO1; CDK15; TNFRSF13B; PLAU; CBFB; GNG5; BANP; SEC22C; NITR9
    receptor binding DECR2; LEPROT; ANGPTL2; F7; CADM2A; JAK2; Icosl; HLA-G; TNFSF4; PARK7

    fgf15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fgf15 here. Most of them are supplied by our site. Hope this information will be useful for your research of fgf15.

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