|Official Full Name||fibroblast growth factor 15|
|Background||Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
Fgf15 involved in several pathways and played different roles in them. We selected most pathways Fgf15 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgf15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|MAPK signaling pathway||FAS; PRKCBA; RASGRF2; PPM1AA; CACNA1G; ARR3A; CACNG4; EGFRA; FGF12A; CASP3A|
|Ras signaling pathway||RALB; TBK1; PLD2; FGF8; HGF; HRAS; KIT; GRIN2B; FGF20; FGF21|
|Rap signaling pathway||PARD3; FARP2; RALB; CALML5; RAP1GAP; APBB1IP; ID1; PLCB1; MLLT4; RAPGEF5|
|PIK-Akt signaling pathway||RXRA; PCK1; IL6R; LAMB2; FGF4; IL3RA; FGFR1; AKT2; NGFR; Kitl|
|Regulation of actin cytoskeleton||BRK1; PIP5K1BB; WAS; PIK3R3A; VCL; ITGAM; RAF1; PIP5K1C; FGF2; GIT1|
|Pathways in cancer||PDGFB; CKS2; MAPK1; WNT16; WNT3A; FASLG; TGFB1; BCL2L1; CTBP2; PRKACG|
|Melanoma||FGF4; TP53; FGF7; AKT1; PDGFC; Pdgfa&Pdgfb; TRP53; FGF20; FGF2; MAP2K2|
Fgf15 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgf15 itself. We selected most functions Fgf15 had, and list some proteins which have the same functions with Fgf15. You can find most of the proteins on our site.
|fibroblast growth factor receptor binding||FGF10; FGF16; FGF6B; FGF8; FGF20A; FGF21; FGF9; FRS2; FGF10B; FGF22|
|growth factor activity||FGF13; FGF1A; PRL2C2; GDF9; FGF22; GDNFA; EPGN; AREG; IL7; INHBC|
|protein binding||RPL23; KLC4; USP12; HIST1H1C; HOMER3; POLR2C; OSBP; CYTH3; SCFD1; TRMT112|
|receptor binding||WNT4B; RARRES2; INSL3; ITGA1; P2RX7; SCYL2; DRD1A; FGF18B; PECR; CADM1B|
Fgf15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgf15 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgf15.