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  • Official Full Name

    fibroblast growth factor 15

  • Overview

    Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
  • Synonyms


  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • Myc
  • DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse Fgf15-499M Recombinant Mouse Fgf15, His-tagged E.coli His
Mouse FGF15-5843M Recombinant Mouse FGF15 Protein Mammalian Cell His
Mouse Fgf15-1213M Recombinant Mouse Fgf15 Protein, His-SUMO-tagged E.coli His/SUMO
Mouse Fgf15-2996M Recombinant Mouse Fgf15 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FGF15-3230M Recombinant Mouse FGF15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fgf15-01M Recombinant Mouse Fgf15 Protein, His-tagged E.coli His 26-218
Mouse FGF15-3230M-B Recombinant Mouse FGF15 Protein Pre-coupled Magnetic Beads HEK293
Rat FGF15-30R Recombinant Rat FGF15 protein, His-tagged E.coli His Gly25~Lys218
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Fgf15 Related Research Area
  • Fgf15 Related Signal Pathway

Fgf15 involved in several pathways and played different roles in them. We selected most pathways Fgf15 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgf15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayCDC42;PLA2G2E;AKT1;Fgf15;RRAS;SHC1;INS2;CALML3;PLA2G2F
Rap signaling pathwayPIK3R3;FGF8;PRKCZ;FGF7;FGF4;PRKD1;FGF14;PIK3R5;FGF12
PIK-Akt signaling pathwayPDPK1;GH2;FGF19;TNXB;GNB3;HRAS;GNG2;TCL1;Reln
Regulation of actin cytoskeletonHRASA;PDGFRA;ITGA2B;FGF4;FGF1;INS2;FGFR3;ITGA6;PIP5K2

Fgf15 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgf15 itself. We selected most functions Fgf15 had, and list some proteins which have the same functions with Fgf15. You can find most of the proteins on our site.

Function Related Protein
fibroblast growth factor receptor bindingFGF1;FGF6A;FGF4;FGF9;FGF10;FGF8A;FGF8B;FGF21;FGF10A
receptor bindingCHRNA10;CD200;PECI;FGF13B;MATK;LAMA2;WNT2BA;CRH;IDH1

Fgf15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgf15 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgf15.

  • Q&As
  • Reviews

Q&As (5)

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In what ways does FGF15 contribute to the regulation of energy homeostasis? 08/13/2022

FGF15 contributes to energy homeostasis by affecting nutrient absorption and metabolism in the small intestine and liver.

Are there ongoing clinical trials involving FGF15 in the treatment of metabolic disorders? 07/16/2022

Yes, there are clinical trials investigating the use of FGF15 analogs or modulators for the treatment of metabolic disorders, including obesity and diabetes.

How does FGF15 impact glucose and lipid metabolism? 06/24/2021

FGF15 plays a role in glucose and lipid metabolism by influencing the expression of genes involved in these processes in the liver.

How is FGF15 linked to the gut-liver axis, and why is it important in clinical research? 07/27/2018

FGF15 is a key player in the gut-liver axis, influencing communication between the gut and the liver. Understanding this axis is crucial for developing targeted therapies for liver and metabolic diseases.

Are there any known side effects or risks associated with FGF15-based therapies? 10/23/2016

The potential side effects and risks of FGF15-based therapies are still under investigation in clinical trials, and the safety profile is not fully established.

Customer Reviews (3)

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    With its remarkable quality, reliability, and the manufacturer's excellent technical support, I am confident that it will be an invaluable asset in driving my scientific inquiries forward and facilitating groundbreaking discoveries in my field.


      This variety allows me to select the most appropriate option based on the specific requirements of my research.


        The manufacturer's commitment to quality control and rigorous testing guarantees the reliability and reproducibility of the FGF15 protein, which is essential for obtaining accurate and consistent results.

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