Fgf15

  • Official Full Name

    fibroblast growth factor 15

  • Background

    Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
  • Synonyms

    FGF19;
    • Type:
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • His (Fc)
    • Avi
    • His|SUMO
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Fgf15-499M Recombinant Mouse Fgf15, His-tagged E.coli His
    Mouse FGF15-5843M Recombinant Mouse FGF15 Protein Mammalian Cell His
    Mouse Fgf15-2996M Recombinant Mouse Fgf15 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse FGF15-3230M Recombinant Mouse FGF15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Fgf15-01M Recombinant Mouse Fgf15 Protein, His-tagged E.coli His
    Mouse Fgf15-1213M Recombinant Mouse Fgf15 Protein, His-SUMO-tagged E.coli His/SUMO
    Mouse FGF15-3230M-B Recombinant Mouse FGF15 Protein Pre-coupled Magnetic Beads HEK293
    Rat FGF15-30R Recombinant Rat FGF15 protein, His-tagged E.coli His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Fgf15 Related Research Area
    • Fgf15 Related Signal Pathway

    Fgf15 involved in several pathways and played different roles in them. We selected most pathways Fgf15 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgf15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathwayMAPKAPK3;TRAF6;FGF3;FGF7;Pdgfa&Pdgfb;FGF13A;HSPA6;TGFB3;PAK2B
    Ras signaling pathwayKITLG;BCL2L1;FGF5;PLA2G4A;PLCE1;FGFR1;PIK3CA;PAK1;SHOC2
    Rap signaling pathwayVASP;MAPK13;VAV2;FGF18;GRIN1;FGF1;MET;FGF14;GRIN2B
    PIK-Akt signaling pathwayITGB7;ANGPT4;SGK1;IFNA16;PGF;TLR2;PPP2R1A;PKN1;DDIT4
    Regulation of actin cytoskeletonACTG1;FGF11;PIK3R3;PIK3CG;ACTN1;MLCK2;SSH1;KRAS;ARPC5L
    Pathways in cancerFGF10;WNT2;TRAF4;FGF3;BCL2L1;BID;CBLB;RALBP1;GNGT1
    MelanomaHGF;PIK3R2;FGF4;PIK3R3;PIK3CA;BRAF;FGF7;BAD;FGF11

    Fgf15 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgf15 itself. We selected most functions Fgf15 had, and list some proteins which have the same functions with Fgf15. You can find most of the proteins on our site.

    Function Related Protein
    fibroblast growth factor receptor bindingFGF18A;FGF8A;FGF20;FGF10A;FGF4;FGF1A;FGF6B;FGF20B;FGF8
    growth factor activityGDF6B;MIA;FGF21;FGF17;FGF20A;GPR19;GPI;FGF6B;GDF2
    protein bindingDNM1L;ATP1A2;TREML1;DPYSL5;ZC3H8;SNX1;EPB41B;CCNB3;DNTTIP1
    receptor bindingCYTL1;POU2F1;ACOX3;ANGPT2;TMED1;NRG1;MPV17L;C1QTNF2;NPY

    Fgf15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgf15 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgf15.

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