FZR1
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Official Full Name
fizzy/cell division cycle 20 related 1
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Overview
Fizzy-related protein homolog is a protein that in humans is encoded by the FZR1 gene. -
Synonyms
FZR1; fizzy/cell division cycle 20 related 1 (Drosophila); fizzy-related protein homolog; CDC20C; CDH1; FZR; FZR2; HCDH; HCDH1; KIAA1242; CDC20-like 1b; cdh1/Hct1 homolog; CDC20-like protein 1;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- Fc
- Avi
- SUMO
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
FZR1 involved in several pathways and played different roles in them. We selected most pathways FZR1 participated on our site, such as Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | E2F3;CETN2;CENPC1;SSNA1;DNA2;RAD21B;CDC25A;SYNE1;SKA1 |
| Ubiquitin mediated proteolysis | SMURF1;UBE2Z;UBE2D2L;CUL1;TCEB1B;NEDD4;SOCS3;CDC34A;FZR1A |
| Progesterone-mediated oocyte maturation | GNAI1;GNAI2A;RPS6KAL;BUB1;CDC26;PRKACBA;MAPK11;CDK1;AKT2 |
FZR1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FZR1 itself. We selected most functions FZR1 had, and list some proteins which have the same functions with FZR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SEMA4C;NEFL;MX2;ATP6V1B2;ALAS1;CDT1;MZB1;SV2B;HDHD2 |
FZR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZR1.
CDC27; MAK; VHL; SIRT2; CLSPN
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewCan be stored at room temperature for several days without deterioration, which allowed us to perform experiments easily and obtain reliable results.
This protein is impressive and provides accurate and reliable experimental data for the research field.
Green and environmentally friendly, with minimal harm to the human body. 0
Q&As (6)
Ask a questionFZR1 protein plays a negative regulatory role in the cell cycle and is involved in mitosis and post-mitosis.
This protein knockdown can lead to the disturbance of cell cycle regulation and affect the mitosis and post-mitosis of cells.
FZR1 protein can undergo post-translational modifications such as phosphorylation and ubiquitination.
This protein interacts with CDK1 (Cyclin-dependent kinase 1) and APC/C (Anaphase Promoting Complex/Cyclosome) protein complexes.
The expression of FZR1 protein fluctuated during the cell cycle and was highly expressed in the late mitotic period.
The phosphorylation of FZR1 protein can regulate its interaction with other proteins and affect its function.
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