Recombinant Human FZR1 Protein, GST-tagged

• Cat.No.: FZR1-4601H
• Product Overview: Human FZR1 full-length ORF ( AAH13413.1, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: FZR1 (Fizzy And Cell Division Cycle 20 Related 1) is a Protein Coding gene. Among its related pathways are PLK1 signaling events and Innate Immune System. An important paralog of this gene is CDC20.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.08 kDa
• AA Sequence: MDQDYERRLLRQIVIQNENTMPRVT EMRRTLTPASSPVSSPSKHGDRFIP SRAGANWSVNFHRINENEKSPSQNR KAKDATSDNGKDGLAYSALLKNELL GAGIEKVQDPQTEDRRLQPSTPEKK GLFTYSLSTKRSSPDDGNDVSPYSL SPVSNKSQKLLRSPRKPTRKISKIP FKVLDAPELQDDFYLNLVDWSSLNV LSVGLGTCVYLWSACTSQVTRLCDL SVEGDSVTSVGWSERGNLVAVGTHK GFVQIWDAAAGKKLSMLEGHTARVG ALAWNAEQLSSGSRDRMILQRDIRT PPLQSERRLQGHRQEVCGLKWSTDH QLLASGGNDNKLLVWNHSSLSPVQQ YTEHLAAVKAIAWSPHQHGLLASGG GTADRCIRFWNTLTGQPLQCIDTGS QVCNLAWSKHANELVSTHGYSQYQI LVWKYPSLTQVAKLTGHSYRVLYLA MSPDGEAIVTGAGDETLRFWNVFSK TRSTKESVSVLNLVTRIR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: FZR1
• Synonyms: FZR1; fizzy/cell division cycle 20 related 1 (Drosophila); fizzy-related protein homolog; CDC20C; CDH1; FZR; FZR2; HCDH; HCDH1; KIAA1242; CDC20-like 1b; cdh1/Hct1 homolog; CDC20-like protein 1
• Gene ID: 51343
• mRNA Refseq: NM_001136197
• Protein Refseq: NP_001129669
• MIM: 603619
• UniProt ID: Q9UM11

Reviews

05/05/2022

Can be stored at room temperature for several days without deterioration, which allowed us to perform experiments easily and obtain reliable results.

08/03/2020

This protein is impressive and provides accurate and reliable experimental data for the research field.

11/25/2019

Green and environmentally friendly, with minimal harm to the human body. 0

Q&As

What is the function of FZR1 protein in the cell cycle?

FZR1 protein plays a negative regulatory role in the cell cycle and is involved in mitosis and post-mitosis.

Why does knocking out FZR1 affect the cell cycle?

This protein knockdown can lead to the disturbance of cell cycle regulation and affect the mitosis and post-mitosis of cells.

What are the post-translational modifications of FZR1 protein?

FZR1 protein can undergo post-translational modifications such as phosphorylation and ubiquitination.

Which cyclins does the FZR1 protein interact with?

This protein interacts with CDK1 (Cyclin-dependent kinase 1) and APC/C (Anaphase Promoting Complex/Cyclosome) protein complexes.

What is the expression pattern of FZR1 protein?

The expression of FZR1 protein fluctuated during the cell cycle and was highly expressed in the late mitotic period.

Why does phosphorylation of FZR1 protein affect its function?

The phosphorylation of FZR1 protein can regulate its interaction with other proteins and affect its function.