MRPL12

  • Official Full Name

    mitochondrial ribosomal protein L12

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.
  • Synonyms

    MRPL12; mitochondrial ribosomal protein L12; RPML12; 39S ribosomal protein L12, mitochondrial; MRPL7; MRPL7/L12; MRP-L12; 5c5-2; L12mt; MRP-L31/34; MGC8610; FLJ60124;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL12-144H Recombinant Human MRPL12, His-tagged HEK293 His
Human MRPL12-4197HCL Recombinant Human MRPL12 293 Cell Lysate HEK293 N/A
Human MRPL12-5074H Recombinant Human MRPL12 Protein (Glu46-Glu198), C-His tagged Mammalian cells C-His
Human MRPL12-2155H Recombinant Human MRPL12 Protein (1-198 aa), GST-tagged E.coli GST
Human MRPL12-5556H Recombinant Human MRPL12 Protein, GST-tagged Wheat Germ GST
Human MRPL12-4876H Recombinant Human MRPL12 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MRPL12-6380HF Recombinant Full Length Human MRPL12 Protein, GST-tagged In Vitro Cell Free System GST
Mouse MRPL12-10044M Recombinant Mouse MRPL12 Protein Mammalian Cell His
Mouse MRPL12-5685M-B Recombinant Mouse MRPL12 Protein Pre-coupled Magnetic Beads HEK293
Mouse MRPL12-5685M Recombinant Mouse MRPL12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Mrpl12-4147M Recombinant Mouse Mrpl12 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque MRPL12-2833R Recombinant Rhesus monkey MRPL12 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MRPL12-2653R-B Recombinant Rhesus Macaque MRPL12 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MRPL12-2653R Recombinant Rhesus Macaque MRPL12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish MRPL12-2454Z Recombinant Zebrafish MRPL12 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MRPL12 involved in several pathways and played different roles in them. We selected most pathways MRPL12 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RibosomeRPL36;RPS19;RPL30;RPL23;RPS9;RPL15;RPL9;MRPL21;MRPL22

MRPL12 has several biochemical functions, for example, RNA binding, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL12 itself. We selected most functions MRPL12 had, and list some proteins which have the same functions with MRPL12. You can find most of the proteins on our site.

Function Related Protein
RNA bindingAGO1;UBR5;RPL21;JMJD6;PABPN1L;EIF3BA;KHDC1;EXOSC6;RCL1
protein bindingMOBKL2B;FAM127B;SLC9A7;KLHL18;NRIP3;HIST1H1C;LGALS3;FOS;DHX15
structural constituent of ribosomeMRPS12;RPLP2L;RPS19;RPS4X;RPL12;RPS17;MRPL47;RPS28;MRPL33

MRPL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL12.

ICT1; Ybx1; RELA; IKBKE; NOA1; RARG; COX6A2; OLIG1; TMEM51; POLR1D; ssrna_ug; Smad6; C1qbp; NS; YBX1; PPP2R2B; MRPL50

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