PDE7A
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Official Full Name
PDE7A phosphodiesterase 7A -
Overview
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3, 5monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE5 enzyme belongs to a family of cGMPdependent PDEs that provide the major means of inactivating the key intracellular second messenger, cGMP -
Synonyms
PDE7A;phosphodiesterase 7A;high affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A;HCP1;TM22;phosphodiesterase isozyme 7;PDE7
Recombinant Proteins
- Human
- Rat
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Sf9 Cells
- Insect Cells
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
Involved Pathway
PDE7A involved in several pathways and played different roles in them. We selected most pathways PDE7A participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | NT5C1BA,CANT1B,ENTPD8,PDE6H,PAPSS2B,IMPDH1,NT5C1AA,GUCY1B3,GUCY2C,GUK1B |
Protein Function
PDE7A has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7A itself. We selected most functions PDE7A had, and list some proteins which have the same functions with PDE7A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3,5-cyclic-AMP phosphodiesterase activity | PDE4B,TDP2B,PDE4C,PDE8B,PDE8A,PDE3A,PDE4D,PDE7B,PDE4A,USB1 |
| metal ion binding | DDHD1B,MOB4,B3GAT2,FDX1L,SMAP2,ZNF486,NT5C2A,SMAD2,ZNF177,EGR4 |
Interacting Protein
PDE7A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7A.
q81n22_bacan
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