Active Recombinant Rat Pde7a protein, GST-tagged
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Cat.No. :
Pde7a-1543R
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant Rat Pde7a(147–482 aa) fused with GST tag at N-terminal was expressed in Insect cells.
Source :
Insect cells
Species :
Rat
Tag :
GST
Form :
45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 18 mM glutathione, 10% glycerol, and 3 mM DTT.
Bio-activity :
≥354 pmol/min/µg.
Molecular Mass :
65 kDa
Unit Definition :
One unit is defined as the amount of enzyme that will convert 1 pmole of 3', 5'-cAMP to 5'-AMP per minute at 37 centigrade.
Applications :
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage :
>6 months at -80 centigrade. Avoid freeze/thaw cycles.
Concentration :
0.34 mg/ml
Figure :
Gene Name :
Pde7a phosphodiesterase 7A [ Rattus norvegicus ]
Official Symbol :
Pde7a
Synonyms :
PDE7A; phosphodiesterase 7A; high affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A; rolipram-insensitive phosphodiesterase type 7; PDE7-1;
Gene ID :
81744
mRNA Refseq :
NM_031080
Protein Refseq :
NP_112342
Chromosome Location :
2q24
Pathway :
G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function :
3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-AMP phosphodiesterase activity; cyclic-nucleotide phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity;
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.