"PDE7A" Related Products

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Recombinant Human PDE7A protein

Cat.No.: PDE7A-356H
Product Overview: Recombinant catalytic domain of human phosphodiesterase 7A was expressed in E. coli.
Description: PDE7A is expressed in immune and pro-inflammatory cells. It is being investigated as an alternate target to PDE4 for the inhibition of inflammation that is associated with many inflammatory diseases including asthma, chronic obstructive pulmonary disease, atopic dermatitis, psoriasis, lupus, rheumatoid arthritis and multiple sclerosis
Source: E. coli
Species: Human
Molecular Mass: 39 kDa
Storage: Long Term Storage: -80 centigrade
Gene Name: PDE7A phosphodiesterase 7A [ Homo sapiens ]
Official Symbol: PDE7A
Synonyms: PDE7A; phosphodiesterase 7A; high affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A; HCP1; TM22; phosphodiesterase isozyme 7; PDE7;
Gene ID: 5150
mRNA Refseq: NM_001242318
Protein Refseq: NP_001229247
MIM: 171885
UniProt ID: Q13946
Chromosome Location: 8q13
Pathway: G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem;
Function: 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-AMP phosphodiesterase activity; hydrolase activity; metal ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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