Recombinant Human PDE7A protein

• Cat.No.: PDE7A-356H
• Product Overview: Recombinant catalytic domain of human phosphodiesterase 7A was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: PDE7A is expressed in immune and pro-inflammatory cells. It is being investigated as an alternate target to PDE4 for the inhibition of inflammation that is associated with many inflammatory diseases including asthma, chronic obstructive pulmonary disease, atopic dermatitis, psoriasis, lupus, rheumatoid arthritis and multiple sclerosis
• Molecular Mass: 39 kDa
• Storage: Long Term Storage: -80 centigrade

Gene Information

• Gene Name: PDE7A phosphodiesterase 7A [ Homo sapiens ]
• Official Symbol: PDE7A
• Synonyms: PDE7A; phosphodiesterase 7A; high affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A; HCP1; TM22; phosphodiesterase isozyme 7; PDE7
• Gene ID: 5150
• mRNA Refseq: NM_001242318
• Protein Refseq: NP_001229247
• MIM: 171885
• UniProt ID: Q13946
• Chromosome Location: 8q13
• Pathway: G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem
• Function: 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-AMP phosphodiesterase activity; hydrolase activity; metal ion binding