USP13

  • Official Full Name

    ubiquitin specific peptidase 13 (isopeptidase T-3)

  • Overview

    Ubiquitin carboxyl-terminal hydrolase 13 is an enzyme that in humans is encoded by the USP13 gene.
  • Synonyms

    USP13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T 3); ubiquitin carboxyl-terminal hydrolase 13; IsoT 3; isopeptidase T-3; ubiquitin thioesterase 13; deubiquitinating enzyme 13; ubiquitin thiolesteras;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human USP13-3616H Recombinant Human USP13 protein, GST-tagged E.coli GST
Human USP13-472HCL Recombinant Human USP13 293 Cell Lysate HEK293 N/A
Human USP13-2322H-B Recombinant Human USP13 Protein Pre-coupled Magnetic Beads HEK293
Human USP13-0352H Recombinant Human USP13 Protein (Q2-S863), GST tagged E.coli GST
Human USP13-0351H Recombinant Human USP13 Protein (Q2-S863), Tag Free E.coli No tag
Human USP13-2648H Recombinant Human USP13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human USP13-2649H Recombinant Human USP13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human USP13-938HFL Recombinant Full Length Human USP13 Protein, C-Flag-tagged Mammalian cells Flag
Human USP13-2322H Recombinant Human USP13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse USP13-17902M Recombinant Mouse USP13 Protein Mammalian Cell His
Mouse USP13-9949M-B Recombinant Mouse USP13 Protein Pre-coupled Magnetic Beads HEK293
Mouse USP13-9949M Recombinant Mouse USP13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Usp13-6864M Recombinant Mouse Usp13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque USP13-5120R Recombinant Rhesus monkey USP13 Protein, His-tagged Mammalian Cell His
Rhesus Macaque USP13-4933R Recombinant Rhesus Macaque USP13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque USP13-4933R-B Recombinant Rhesus Macaque USP13 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish USP13-5676Z Recombinant Zebrafish USP13 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • USP13 Related Articles

USP13 involved in several pathways and played different roles in them. We selected most pathways USP13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USP13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

USP13 has several biochemical functions, for example, BAT3 complex binding, chaperone binding, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP13 itself. We selected most functions USP13 had, and list some proteins which have the same functions with USP13. You can find most of the proteins on our site.

Function Related Protein
BAT3 complex bindingVCP;SGTA;USP13;AMFR
chaperone bindingPACRG;HSCB;UBL4;CTSC;TBCE;PFDN6;HSP104;AHSA2;CDC37
cysteine-type endopeptidase activityCTSBA;USP13;USP22;CTSC;USP9;LGMN;USP49;MALT1A;USP51
omega peptidase activityAPEH;ATXN3;UCHL1;JOSD2;USP5;ATXN3L;JOSD1;USP13;GGH
proteasome bindingPSMF1;ADRM1;PSMD14;DNAJB2;USP14;ID1;UCHL5;BAG6;PSMG1
protein bindingRICTOR;TRAF3;FMR1;STX18;DUSP2;ZNF136;ARPIN;DLX2;REST
ubiquitin bindingTOP2A;UBXN1;SHRPRBCK1R;UBXN2B;USP16;SPRTN;RNF168;FAN1;BCL10
ubiquitin protein ligase bindingNPLOC4;SMAD3;PIAS1;CASP8;UBE2G1;BLZF1;PER1;SMC6;BECN1
ubiquitin-like protein ligase bindingVCP;CEBPB;DDRGK1;TRIP4;USP13;CDK5RAP3
ubiquitin-specific protease activityBAP1;USP16;USP2;USP30;JOSD2;USP1;USP27X;OTUD5B;USP17L2
ubiquitin-specific protease activity involved in positive regulation of ERAD pathway
zinc ion bindingUSP5;TRIM10;RNF166;ZC3HC1;MMP17;LIN28A;ATRX;KDM2AA;MANEA

USP13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP13 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP13.

SMC1A; SMC3; UBL4A; DLST; USP5; BAG6; ATXN3; OGDH; NEDD8; NPLOC4; UFD1L; FAF2; ITCH; KCTD10; CACYBP; CYLD; DIABLO; TCAF1

Xiang, SJ; Fang, JQ; et al. MicroRNA-135b regulates the stability of PTEN and promotes glycolysis by targeting USP13 in human colorectal cancers. ONCOLOGY REPORTS 33:1342-1348(2015).
Liu, YF; Soetandyo, N; et al. USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation. ELIFE 3:-(2014).
  • Q&As
  • Reviews

Q&As (5)

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Can USP13 be a potential therapeutic target for neurodegenerative diseases? 02/09/2022

There is emerging research suggesting that USP13 may play a role in neurodegenerative diseases, and targeting it could be a potential avenue for therapeutic intervention.

How does USP13 interact with other proteins in cellular pathways? 07/26/2021

USP13 interacts with various proteins, forming complexes that regulate different cellular pathways. Understanding these interactions is crucial for deciphering its role in health and disease.

Are there any known genetic variations in the USP13 gene associated with disease susceptibility? 02/17/2021

Genetic variations in the USP13 gene have been studied, and certain polymorphisms may be associated with an increased risk of specific diseases. Further research is ongoing in this area.

In what other medical conditions is USP13 protein being investigated? 03/22/2019

Researchers are exploring the role of USP13 in neurodegenerative diseases, inflammatory disorders, and other conditions where ubiquitin-mediated processes play a crucial role.

How does USP13 influence cellular response to stress and DNA damage? 04/03/2016

USP13 has been found to regulate the stability of proteins involved in the DNA damage response, affecting how cells respond to stress and maintain genomic integrity.

Customer Reviews (3)

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Reviews
01/02/2023

    Its purity, integrity, and consistency ensure reliable and reproducible results, which are essential for meaningful scientific discoveries.

    06/29/2016

      Their in-depth understanding of the protein's characteristics, applications, and potential limitations allows for valuable insights and recommendations, ensuring the success of my experiments.

      04/07/2016

        Whether it's troubleshooting, protocol optimization, or general inquiries, their knowledgeable and responsive team is readily available to assist and solve any problems that may arise during the experimental process.

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