USP13 involved in several pathways and played different roles in them. We selected most pathways USP13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USP13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
USP13 has several biochemical functions, for example, BAT3 complex binding, chaperone binding, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP13 itself. We selected most functions USP13 had, and list some proteins which have the same functions with USP13. You can find most of the proteins on our site.
| Function |
Related Protein |
| BAT3 complex binding |
USP13; VCP; SGTA; AMFR |
| chaperone binding |
HYOU1; PACRG; CLU; TFRC; DNAJB5; DNAJB8; DLST; CALR; UBL4; USP13 |
| cysteine-type endopeptidase activity |
USP48; CTSSB.1; CASP9; CASP3A; CTS7; CTSL2; USP18; USP42; CTSM; USP50 |
| omega peptidase activity |
JOSD2; USP5; GGH; ATXN3L; UCHL5; USP13; ATXN3; UCHL1; JOSD1; APEH |
| proteasome binding |
BAG6; UBD; USP13; UCHL5; PSMG1; ADRM1; PSMD14; PSMF1; USP14; DNAJB2 |
| protein binding |
NECAB3; IFNA4; Raet1c; RUSC1-AS1; PCM1; C1R; MAPK9; BLK; RAN; C22orf39 |
| ubiquitin binding |
FAF2; IDE; NBR1; UBXN2A; SHRPRBCK1R; UCHL1; OTUB1B; OTUB1A; SIRT2; BRAP |
| ubiquitin protein ligase binding |
POLR2A; ZFP746; RRAGA; TCP1; CDC34A; CCT2; GPI; DNAJA1; USP25; SMAD7 |
| ubiquitin-like protein ligase binding |
DDRGK1; VCP; USP13; TRIP4; CDK5RAP3; CEBPB |
| ubiquitin-specific protease activity |
FMNL3; OTUD7A; USP44; USP50; BAP1; COPS5; USP27X; USP45; OTUB1; USP12 |
| ubiquitin-specific protease activity involved in positive regulation of ERAD pathway |
USP13 |
| zinc ion binding |
PGLYRP3; RNF11A; RAG2; CHMP1A; ABLIM2; CRIP2; AKAP8; APOBEC2A; CIZ1; BRPF1 |
USP13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP13 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP13.
SMC1A; SMC3; UBL4A; DLST; USP5; BAG6; ATXN3; OGDH; NEDD8; NPLOC4; UFD1L; FAF2; ITCH; KCTD10; CACYBP; CYLD; DIABLO; TCAF1
Xiang, SJ; Fang, JQ; et al. MicroRNA-135b regulates the stability of PTEN and promotes glycolysis by targeting USP13 in human colorectal cancers. ONCOLOGY REPORTS 33:1342-1348(2015).
Liu, YF; Soetandyo, N; et al. USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation. ELIFE 3:-(2014).
