Recombinant Full Length Human USP13 Protein, C-Flag-tagged

• Cat.No.: USP13-938HFL
• Product Overview: Recombinant Full Length Human USP13 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables several functions, including BAT3 complex binding activity; chaperone binding activity; and cysteine-type peptidase activity. Involved in several processes, including maintenance of unfolded protein involved in ERAD pathway; regulation of cellular catabolic process; and regulation of transcription, DNA-templated. Acts upstream of or within protein deubiquitination and protein stabilization. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 97.1 kDa
• AA Sequence: MQRRGALFGMPGGSGGRKMAAGDIG ELLVPHMPTIRVPRSGDRVYKNECA FSYDSPNSEGGLYVCMNTFL AFGREHVERHFRKTGQSVYMHLKRH VREKVRGASGGALPKRRNSKIFLDL DTDDDLNSDDYEYEDEAKLV IFPDHYEIALPNIEELPALVTIACD AVLSSKSPYRKQDPDTWENELPVSK YANNLTQLDNGVRIPPSGWK CARCDLRENLWLNLTDGSVLCGKWF FDSSGGNGHALEHYRDMGYPLAVKL GTITPDGADVYSFQEEEPVL DPHLAKHLAHFGIDMLHMHGTENGL QDNDIKLRVSEWEVIQESGTKLKPM YGPGYTGLKNLGNSCYLSSV MQAIFSIPEFQRAYVGNLPRIFDYS PLDPTQDFNTQMTKLGHGLLSGQYS KPPVKSELIEQVMKEEHKPQ QNGISPRMFKAFVSKSHPEFSSNRQ QDAQEFFLHLVNLVERNRIGSENPS DVFRFLVEERIQCCQTRKVR YTERVDYLMQLPVAMEAATNKDELI AYELTRREAEANRRPLPELVRAKIP FSACLQAFSEPENVDDFWSS ALQAKSAGVKTSRFASFPEYLVVQI KKFTFGLDWVPKKFDVSIDMPDLLD INHLRARGLQPGEEELPDIS PPIVIPDDSKDRLMNQLIDPSDIDE SSVMQLAEMGFPLEACRKAVYFTGN MGAEVAFNWIIVHMEEPDFA EPLTMPGYGGAASAGASVFGASGLD NQPPEEIVAIITSMGFQRNQAIQAL RATNNNLERALDWIFSHPEF EEDSDFVIEMENNANANIISEAKPE GPRVKDGSGTYELFAFISHMGTSTM SGHYICHIKKEGRWVIYNDH
  KVCASERPPKDLGYMYFYRRIPSTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease

Gene Information

• Gene Name: USP13 ubiquitin specific peptidase 13 [ Homo sapiens (human) ]
• Official Symbol: USP13
• Synonyms: ISOT3; IsoT-3
• Gene ID: 8975
• mRNA Refseq: NM_003940.3
• Protein Refseq: NP_003931.2
• MIM: 603591
• UniProt ID: Q92995