Recombinant Human USP13 Protein, His (Fc)-Avi-tagged

• Cat.No.: USP13-2322H
• Product Overview: Recombinant Human USP13 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: USP13 ubiquitin specific peptidase 13 [ Homo sapiens (human) ]
• Official Symbol: USP13
• Synonyms: ISOT3; IsoT-3
• Gene ID: 8975
• mRNA Refseq: NM_003940.3
• Protein Refseq: NP_003931.2
• MIM: 603591
• UniProt ID: Q92995

Reviews

01/02/2023

Its purity, integrity, and consistency ensure reliable and reproducible results, which are essential for meaningful scientific discoveries.

06/29/2016

Their in-depth understanding of the protein's characteristics, applications, and potential limitations allows for valuable insights and recommendations, ensuring the success of my experiments.

04/07/2016

Whether it's troubleshooting, protocol optimization, or general inquiries, their knowledgeable and responsive team is readily available to assist and solve any problems that may arise during the experimental process.

Q&As

Can USP13 be a potential therapeutic target for neurodegenerative diseases?

There is emerging research suggesting that USP13 may play a role in neurodegenerative diseases, and targeting it could be a potential avenue for therapeutic intervention.

How does USP13 interact with other proteins in cellular pathways?

USP13 interacts with various proteins, forming complexes that regulate different cellular pathways. Understanding these interactions is crucial for deciphering its role in health and disease.

Are there any known genetic variations in the USP13 gene associated with disease susceptibility?

Genetic variations in the USP13 gene have been studied, and certain polymorphisms may be associated with an increased risk of specific diseases. Further research is ongoing in this area.

In what other medical conditions is USP13 protein being investigated?

Researchers are exploring the role of USP13 in neurodegenerative diseases, inflammatory disorders, and other conditions where ubiquitin-mediated processes play a crucial role.

How does USP13 influence cellular response to stress and DNA damage?

USP13 has been found to regulate the stability of proteins involved in the DNA damage response, affecting how cells respond to stress and maintain genomic integrity.