foxp1
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  • Official Full Name
  • forkhead box P1
  • Background
  • This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Synonyms
  • FOXP1; forkhead box P1; QRF1; 12CC4; hFKH1B; HSPC215; forkhead box protein P1; glutamine-rich factor 1; fork head-related protein like B;
Cat.#:FOXP1-12984HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FOXP1, GST-tagged
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Cat.#:FOXP1-12HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FOXP1 protein, GST-tagged
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Cat.#:FOXP1-16HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human FOXP1 protein, DDK-tagged
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Cat.#:FOXP1-28111THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FOXP1, His-tagged
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Cat.#:FOXP1-7636HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FOXP1 protein, His & T7-tagged
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Cat.#:FOXP1-6010MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FOXP1 Protein
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Cat.#:Foxp1-7637MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Foxp1 protein, His & T7-tagged
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Cat.#:FOXP1-2388RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FOXP1 Protein
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Cat.#:FOXP1-1744RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FOXP1 Protein, His-tagged
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Cat.#:FOXP1-2197CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FOXP1
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Cat.#:FOXP1-6146HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FOXP1 293 Cell Lysate
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Involved Pathway

FOXP1 involved in several pathways and played different roles in them. We selected most pathways FOXP1 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXP1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MicroRNAs in cancer
PIK3R2; BMPR2; ITGB3; ABL1; ERBB2; ABCC1; EZH2; TRIM71; SLC45A3; MAPK1

Protein Function

FOXP1 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding, androgen receptor binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXP1 itself. We selected most functions FOXP1 had, and list some proteins which have the same functions with FOXP1. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein POU5F1; ATF4B1; SP3; HIF1AB; FOXB1; RUNX2A; FOXN1; ETS1; SIM1; FOXN2B
Function androgen receptor binding
Related Protein DDX5; CDK7; PARK7; NCOA4; CTNNB1; EP300; NSD1; FOXP1; KDM1A; TRIM68
Function metal ion binding
Related Protein ZFP57; ACVRL1; GLI3; ATP13A1; ZNF274; CYB561A3A; Scd1; ZBTB48; B3GAT3; ZFP821
Function protein binding
Related Protein DACH1; HMGN2; KLF15; KRT16; DSN1; PTPRE; ZWILCH; SOSTDC1B; EVL; TTN
Function sequence-specific DNA binding
Related Protein HOXA4A; POU5F3; HOXA1; PBX2; ZNF394; ZNF498; FOXF2A; ZFP110; CENPB; HLF

Interacting Protein

FOXP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXP1.
LRRK1; IL3RA; alaS; mglA3; q7cia4_yerpe; opuD; ppk; gabD; mdtB; arre2_element_mouse_il2_promoter; MYC

FOXP1 Related Articles

Hu, ZH; Zhu, LC; et al. The expression and correlation between the transcription factor FOXP1 and estrogen receptors in epithelial ovarian cancer. BIOCHIMIE 109C:42-48(2015).
Gringhuis, SI; Kaptein, TM; et al. Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production. NATURE COMMUNICATIONS 5:-(2014).