Recombinant Human FOXP1, His-tagged

• Cat.No.: FOXP1-28111TH
• Product Overview: Recombinant fragment, corresponding to amino acids 80-427 of Human FOXP1 with N terminal His tag; Predicted MWt 40 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 80-427 a.a.
• Description: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 162 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: GLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQ VLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQ LLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQH LLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWK EVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNP HASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWP GCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQ QLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVS SVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTT
• Sequence Similarities: Contains 1 C2H2-type zinc finger.Contains 1 fork-head DNA-binding domain.

Gene Information

• Gene Name: FOXP1 forkhead box P1 [ Homo sapiens ]
• Official Symbol: FOXP1
• Synonyms: FOXP1; forkhead box P1; forkhead box protein P1; 12CC4; fork head related protein like B; glutamine rich factor 1; hFKH1B; HSPC215; PAX5/FOXP1 fusion protein; QRF1
• Gene ID: 27086
• mRNA Refseq: NM_001012505
• Protein Refseq: NP_001012523
• MIM: 605515
• Uniprot ID: Q9H334
• Chromosome Location: 3p14.1
• Function: DNA bending activity; chromatin binding; double-stranded DNA binding; metal ion binding; protein heterodimerization activity