Description : |
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
75.1 kDa |
AA Sequence : |
MMQESGTETKSNGSAIQNGSGGSNH LLECGGLREGRSNGETPAVDIGAAD LAHAQQQQQQALQVARQLLLQQQQQ QQVSGLKSPKRNDKQPALQVPVSVA MMTPQVITPQQMQQILQQQVLSPQQ LQVLLQQQQALMLQQQQLQEFYKKQ QEQLQLQLLQQQHAGKQPKEQQQVA TQQLAFQQQLLQMQQLQQQHLLSLQ RQGLLTIQPGQPALPLQPLAQGMIP TELQQLWKEVTSAHTAEETTGNNHS SLDLTTTCVSSSAPSKTSLIMNPHA STNGQLSVHTPKRESLSHEEHPHSH PLYGHGVCKWPGCEAVCEDFQSFLK HLNSEHALDDRSTAQCRVQMQVVQQ LELQLAKDKERLQAMMTHLHVKSTE PKAAPQPLNLVSSVTLSKSASEASP QSLPHTPTTPTAPLTPVTQGPSVIT TTSMHTVGPIRRRYSDKYNVPISSA DIAQNQEFYKNAEVRPPFTYASLIR QAILESPEKQLTLNEIYNWFTRMFA YFRRNAATWKNAVRHNLSLHKCFVR VENVKGAVWTVDEVEFQKRRPQKIS GNPSLIKNMQSSHAYCTPLSAALQA SMAENSIPLYTTASMGNPTLGNLAS AIREELNGAMEHTNSNESDSSPGRS PMQAVHPVHVKEEPLDPEEAEGPLS LVTTANHSPDFDHDRDYEDEPVNED METRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |