ppp1cc
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  • Official Full Name
  • protein phosphatase 1, catalytic subunit, gamma isozyme
  • Background
  • Protein phosphatase 1, gamma 1 (PP-1G) is a member of the PPP phosphatase family. Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR.
  • Synonyms
  • PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme; protein phosphatase 1, catalytic subunit, gamma isoform; serine/threonine-protein phosphatase PP1-gamma catalytic subunit; PP1gamma; serine/threonine phosphatase 1 gamma; protein phosphatase 1C catalytic subunit; PP-1G; PPP1G
Cat.#:PPP1CC-2401HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 1, Catalytic Subunit, Gamma Isozyme, His-tagged
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Cat.#:PPP1CC-29101THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PPP1CC
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Cat.#:PPP1CC-648HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-844HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC, His-tagged
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Cat.#:PPP1CC-13211MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPP1CC Protein
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Cat.#:PPP1CC-3559RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-1339CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPP1CC
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Cat.#:PPP1CC-2948HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP1CC 293 Cell Lysate
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Involved Pathway

PPP1CC involved in several pathways and played different roles in them. We selected most pathways PPP1CC participated on our site, such as mRNA surveillance pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1CC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
mRNA surveillance pathway
PPP2CB; PABPC5; CPSF3; PPP2R3A; PABPN1; MAGOHB; UPF3A; EIF4A3; UPF1; PABPC4
cGMP-PKG signaling pathway
ATP2A3; MEF2D; PRKG1; ATP2B4; OPRD1; PIK3CB; MEF2A; NFATC3; RHOA; ATP1A1
cAMP signaling pathway
ATP1B2; GNAI3; ARAP3; PIK3CB; TNNI3; ROCK1; ATP1A2; VAV1; PPARA; GLI3
Oocyte meiosis
CALM3; MAPK12B; CAMK2D2; CALML3; CALM4; PTTG1; CALM3B; SMC1A; PRKACAB; YWHABL
Adrenergic signaling in cardiomyocytes
CACNB2A; ADRA1BB; TPM3; CALM2; AGTR1B; ADRB3A; NETO2; PPP2CA; AKT2; TNNT2
Vascular smooth muscle contraction
PPP1CBL; PLA2G4A; KCNMB2; Adcy4; RAF1; RHOAB; CALCRLA; AGTR1A; KCNMB1; PLA2G2F
Hippo signaling pathway
YWHAH; WNT7A; GDF6; ID1; PPP2R2D; BIRC2; SMAD4; FZD8; ITGB2L; WNT7B
Focal adhesion
HRAS; PDPK1B; PDGFA; ITGA11A; LAMB1; RHOAD; VWF; PTK6; ITGA2B; COL4A1
Platelet activation
PLA2G4F; PIK3CA; APBB1IP; GNAI1; PRKG1; PPP1CC; FERMT3; ITGB3; PTGIR; PPP1CA
Long-term potentiation
CAMK2G; RPS6KA3; ARAF; RPS6KA2; CAMK2D; RAP1A; PRKCA; PPP1R1A; PPP1CB; GRIN2A
Dopaminergic synapse
CREB3L3; ITPR3; MAPK12; PPP2R1A; KIF5C; CREB3L1; GNAI2; KCNJ3; GNG12; GNGT2
Inflammatory mediator regulation of TRP channels
PLCG1; HTR2A; IL1R1; IL1RAP; IL1B; F2RL1; NTRK1; CYP4A14; CYP2C70; PIK3CD
Regulation of actin cytoskeleton
RDX; WASL; VAV1; SSH1; MAP2K2B; FGFR1; F2; PTK2AB; PFN3; HRASA
Insulin signaling pathway
GRB2B; LIPE; MKNK2; GYS1; G6PC; PDPK1; G6PCA.2; SREBF1; PPP1R3B; FLOT1A
Oxytocin signaling pathway
CACNA2D4; CACNB2; PLA2G4F; PRKAG3; CACNG6; PPP1R12B; GNAI1; PRKAG2; MYLK2; PPP1CC
Insulin resistance
SLC27A1A; CREB3L1; FOXO1A; SOCS3B; PRKAA1; OGT.1; PYGL; RPS6KAL; G6PCA.1; PPP1R3A
Amphetamine addiction
DRD1; SLC14A2; NETO2; GRIN2D; PPP1CC; PRKACB; STX1A; HDAC1; ATF4; PRKACG
Alcoholism
CREB3L4; GNGT1; HDAC8; HIST1H2BB; GNG10; SHC2; HIST1H2BN; HIST2H2AA4; GNG2; HIST1H4G
Herpes simplex infection
SRPK1A; NXF3; STAT1B; STAT2; EIF2AK1; SRSF2B; MAPK8; CDK1; SRSF2A; STAT1A
Proteoglycans in cancer
PRKCB; PRKACB; RRAS2; PIK3R3; TP53; HRAS; PIK3CG; ITGAV; SDC2; CBL

Protein Function

PPP1CC has several biochemical functions, for example, metal ion binding, phosphatase activity, phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1CC itself. We selected most functions PPP1CC had, and list some proteins which have the same functions with PPP1CC. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein ERI1; FBP1; MMP13A; ZNF683; AGBL1; ATP2B1; TNNI3K; THAP2; ASH2L; MGRN1A
Function phosphatase activity
Related Protein PTPN11A; CDC14A; PTPRUB; PGAM5; CTDNEP1; CAR3; SSH2B; CTDSPL2B; DUSP23A; TIGARB
Function phosphoprotein phosphatase activity
Related Protein PPP1R3B; PPM1BB; PPEF2; CDC14AA; PPM1LA; CDC25D; PTPRFB; PTPRUB; PPM1H; PTPN2B
Function poly(A) RNA binding
Related Protein RNPS1; PSIP1; GTPBP1; CPSF6; RPS12; EIF4B; TSNAX; BZW1; CORO1A; PARP12
Function protein N-terminus binding
Related Protein SCFD1; ERCC3; PDLIM5; MYO7A; SNCA; NBN; CSNK2A1; NCOA1; RPS21; EIF5A
Function protein binding
Related Protein PPP4R2; HEBP2; RGS17; FUBP3; G3BP2; EIF3J; PML; LACE1; LRRK1; GABARAP
Function protein kinase binding
Related Protein ATG13; PEBP1; PPP1R12C; NGFRAP1; ZC3HC1; USF1; BCL2L1; CCNB3; MAP3K2; TICAM1
Function protein serine/threonine phosphatase activity
Related Protein DUSP23A; PPP2R5D; TAB1; PPP1CC; PPM1H; PPM1J; MTMR6; PDP1; PPM1N; PPEF2

Interacting Protein

PPP1CC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1CC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1CC.
TP53BP2; PPP1R2; ZFYVE9; URI1