ppp1cc
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  • Official Full Name
  • protein phosphatase 1, catalytic subunit, gamma isozyme
  • Background
  • Protein phosphatase 1, gamma 1 (PP-1G) is a member of the PPP phosphatase family. Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR.
  • Synonyms
  • PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme; protein phosphatase 1, catalytic subunit, gamma isoform; serine/threonine-protein phosphatase PP1-gamma catalytic subunit; PP1gamma; serine/threonine phosphatase 1 gamma; protein phosphatase 1C catalytic subunit; PP-1G; PPP1G
Cat.#:PPP1CC-2401HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 1, Catalytic Subunit, Gamma Isozyme, His-tagged
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Cat.#:PPP1CC-29101THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PPP1CC
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Cat.#:PPP1CC-648HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-844HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC, His-tagged
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Cat.#:PPP1CC-13211MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPP1CC Protein
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Cat.#:PPP1CC-3559RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-1339CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPP1CC
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Cat.#:PPP1CC-2948HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP1CC 293 Cell Lysate
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Involved Pathway

PPP1CC involved in several pathways and played different roles in them. We selected most pathways PPP1CC participated on our site, such as mRNA surveillance pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1CC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
mRNA surveillance pathway
PPP2CA; WDR82; MAGOH2; DDX39B; PABPC1B; CPSF3; PPP2R2D; PPP2CB; FIP1L1; ETF1A
cGMP-PKG signaling pathway
PPP1CA; PPP3R2; ATP2B1; ATP1B3; ATP1A4; IRS2; PDE2A; MAP2K2; KCNMB3; ATP1B2
cAMP signaling pathway
DRD1A; CNGA1; GRIN2A; BRAF; ATP1B4; ORAI1; NFKBIA; RYR2; LOC100328615; VAV1
Oocyte meiosis
MAD2L1; PPP2CB; CPEB1; PTTG1; REC8B; CUL1B; PLK1; PPP2R5EB; MAPK12; ANAPC7
Adrenergic signaling in cardiomyocytes
PPP2R5B; SLC8A1; MAPK12A; CACNG7; PPP1CAA; ATP1A1; ATP1A1A.1; MYL3; CREB5; PRKACBA
Vascular smooth muscle contraction
AVPR1B; PLA2G5; PRKCE; PPP1R14AA; PPP1CAA; ADORA2AB; MAP2K2B; MAP2K2A; ITPR1; ACTG2
Hippo signaling pathway
PRKCI; APC; AXIN2; WNT8A; FZD7; TGFBR2; WNT11; WNT7B; PARD6B; SOX2
Focal adhesion
ROCK2A; RAC2; ROCK2B; BCL2A; COL4A2; PARVB; MYL7; VTNB; SPP1; PIK3CB
Platelet activation
SNAP23; PRKG2; PRKACB; PPP1R12A; ITPR1; P2RX1; PRKCI; PRKACA; MYLK3; PTGS1
Long-term potentiation
PPP3R1; NRAS; RPS6KA6; CALM1; PRKACA; PRKACB; KRAS; MAPK3; GRIA1; MAP2K1
Dopaminergic synapse
DRD3; PPP2CB; PPP2R3A; PRKACB; PPP2R3C; GNAS; GNAO1; GSK3A; CALM4; MAPK12
Inflammatory mediator regulation of TRP channels
ACCN4; PIK3CA; ACCN3; CAMK2D; TRPV4; PLCB4; F2RL1; PRKCG; CALM1; PTGER4
Regulation of actin cytoskeleton
FGFR2; PIP4K2AA; VAV3B; ITGA2B; ARHGEF7; DIAPH3; ARHGEF1; DIAP3; FN1A; VAV1
Insulin signaling pathway
G6PCA.1; SOCS9; CBL; SOCS1; PHKA2; EIF4E1C; PRKAG2; AKT1; MAPK10; BADB
Oxytocin signaling pathway
NFATC1; KCNJ14; RYR1; GUCY1A3; RYR2; CACNG8; PRKAG2; RGS2; PRKAG3; PTGS2
Insulin resistance
CRTC2; TNFRSF1A; PYGM; PRKAB1A; SLC27A3; PPARA; CREB5; SLC27A1A; TNF; IKBKB
Amphetamine addiction
GRIN2D; CAMK2A; CAMK2D; ATF4; GRIN2A; GRIN2B; NETO2; TH; MAOA; CREB3L3
Alcoholism
HIST3H2A; GNG8; HIST1H2AI; CREB5; H2AFJ; HIST2H2AA4; HDAC9; HIST1H4K; GNB5; GNG2
Herpes simplex infection
IFNA10; GLTSCR2; HNRPKL; HLA-DPA1; FB06F03; IFNA13; CCL5; IRF7; PTPN11A; TAF6L
Proteoglycans in cancer
SLC9A1; GPC1; SMO; BRAF; ANK2; HRAS; TLR2; PPP1CB; TLR4; PPP1R12C

Protein Function

PPP1CC has several biochemical functions, for example, metal ion binding, phosphatase activity, phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1CC itself. We selected most functions PPP1CC had, and list some proteins which have the same functions with PPP1CC. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein DNAJA3B; ZNF567; ZSCAN12; MMP14A; BMPR1A; LRRK1; CHN1; KLF3; ZIK1; ZNF550
Function phosphatase activity
Related Protein ACPL2; CTDNEP1; MINPP1B; SACM1LA; PTPRJ; MTMR7B; PTPREB; SACM1L; PTPRU; PTPRDB
Function phosphoprotein phosphatase activity
Related Protein SSH2; CPPED1; CTDSPL2B; PTPRDB; PPP3CCA; PPM1DA; PPP1R3B; PTPRJA; PPP1CAB; PPP3CB
Function poly(A) RNA binding
Related Protein TNS1; PUS1; DDX18; C1orf131; SPATS2L; RPL23; NCBP1; RBM14; MRPL28; DHX16
Function protein N-terminus binding
Related Protein SDCBP; PIAS3; SERPINB1A; STX1A; CSNK2A2; DAXX; RBPJ; TAF11; EIF5A; DCN
Function protein binding
Related Protein TGS1; REV1; CRIPT; EFS; RAB6B; NRG4; RPAP3; CCT8; CENPH; ZNF2
Function protein kinase binding
Related Protein B4GALT1; CHRNA7; SPDYB; SFN; ATP1A1; CACNB3; ACVRL1; CAV2; TSKS; KIF14
Function protein serine/threonine phosphatase activity
Related Protein CDC14AA; PPP2R1A; DULLARD; PPP1R15B; PPM1LA; TIMM50; PP2D1; CTDNEP1; TAB1; PPM1BA

Interacting Protein

PPP1CC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1CC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1CC.
TP53BP2; PPP1R2; ZFYVE9; URI1