ppp1cc
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  • Official Full Name
  • protein phosphatase 1, catalytic subunit, gamma isozyme
  • Background
  • Protein phosphatase 1, gamma 1 (PP-1G) is a member of the PPP phosphatase family. Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR.
  • Synonyms
  • PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme; protein phosphatase 1, catalytic subunit, gamma isoform; serine/threonine-protein phosphatase PP1-gamma catalytic subunit; PP1gamma; serine/threonine phosphatase 1 gamma; protein phosphatase 1C catalytic subunit; PP-1G; PPP1G
Cat.#:PPP1CC-2401HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 1, Catalytic Subunit, Gamma Isozyme, His-tagged
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Cat.#:PPP1CC-29101THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PPP1CC
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Cat.#:PPP1CC-648HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-844HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC, His-tagged
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Cat.#:PPP1CC-13211MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPP1CC Protein
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Cat.#:PPP1CC-3559RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-1339CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPP1CC
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Cat.#:PPP1CC-2948HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP1CC 293 Cell Lysate
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Involved Pathway

PPP1CC involved in several pathways and played different roles in them. We selected most pathways PPP1CC participated on our site, such as mRNA surveillance pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1CC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
mRNA surveillance pathway
PPP2R5B; PPP2R2CA; CSTF2T; RNMT; PPP1CAB; SMG6; RBM8A; PABPC1B; MSI2B; pab1
cGMP-PKG signaling pathway
AKT1; GNAI3; ATP1A2; PRKG1; PDE3B; ATP1B3; VDAC1; PDE5A; CREB3L2; MAPK3
cAMP signaling pathway
ARAP3; ATP1A3; AKT2; ACOX3; AMH; PAK1; NFKBIA; F2R; TSHR; MAP2K1
Oocyte meiosis
CUL1; FBXW11B; CALM1A; RPS6KA1; Ar; YWHAQA; CAMK2D1; RPS6KA6; PRKACA; CAMK2B
Adrenergic signaling in cardiomyocytes
PLN; MAPK12B; CACNB1; MYL2; ADRA1B; MAPK14A; ADRB2; CACNG1A; CACNA2D1; GNAI2
Vascular smooth muscle contraction
RHOAD; MAPK1; CYP4A10; KCNMA1A; AVPR1B; ADCY2B; ROCK1; PLA2G4D; CALM3; PLA2G12B
Hippo signaling pathway
ACTB; WNT9A; FZD10; WNT8B; ACTG1; FRMD6; BMP8B; WNT7B; CRB2; PPP1CC
Focal adhesion
PIK3R3A; HRASA; COL6A1; PIK3R3; COL11A1A; MET; BADB; LAMA1; ITGA3; BCAR1
Platelet activation
RAP1A; PTGIR; ITGA2; PLCB3; GUCY1A3; PIK3R5; F2R; AKT2; P2RY1; PIK3R2
Long-term potentiation
CALM3; ARAF; KRAS; CALML3; GRIA1; PLCB1; MAP2K1; NRAS; PPP1CA; CALM4
Dopaminergic synapse
GRIA4; ATF6B; CALM4; PPP2R5C; KIF5B; PRKCB; GNAI3; MAPK13; GNGT1; PPP2R3A
Inflammatory mediator regulation of TRP channels
PLA2G4C; PIK3CG; PLA2G6; PPP1CC; TRPV1; PIK3CA; HTR2A; CYP2J5; PPP1CA; PPP1CB
Regulation of actin cytoskeleton
FGF11A; PPP1CBL; MYL5; ARHGEF1; PAK2A; HRASB; ITGA1; SSH3; NRAS; ARPC5LB
Insulin signaling pathway
CALM2A; PCK1; PHKA1; PRKAR1A; AKT2L; PRKAR2AB; PRKACG; KRAS; PDPK1B; IKBKB
Oxytocin signaling pathway
MYL9; CALM1; PLA2G4A; CACNA2D3; PPP1CA; PIK3R1; GNAI2; PLA2G4F; RYR2; PRKAB1
Insulin resistance
CREB3L1; PPP1CA; IRS1; SLC27A1B; PPARA; CREB3L2; TNF; PPP2R4; PPP1R3D; PDPK1B
Amphetamine addiction
MAOA; DRD1; PPP3CA; GRIN2D; PPP1CA; PRKCG; CAMK4; GRIA3; CREB5; CALM1
Alcoholism
HDAC2; HIST2H2BB; GRB2; CREB3L4; H2AFX; GNG11; DDC; H3F3B; HDAC4; HIST1H2BC
Herpes simplex infection
SFRS9; PVRL2; TAF3; MHC2DEB; TRAF3; TRAF2; TLR2-1; HLA-DMB; Hc; HLA-DOA
Proteoglycans in cancer
HPSE; ERBB4; PIK3R1; WNT7B; CCND1; PXN; EZR; ERBB3; TRP53; NRAS

Protein Function

PPP1CC has several biochemical functions, for example, metal ion binding, phosphatase activity, phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1CC itself. We selected most functions PPP1CC had, and list some proteins which have the same functions with PPP1CC. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein TDP2B; ZNF329; MOB2; BMI1B; ZSCAN2; MGAT4C; CYP2P8; RBM26; RBM22; ZNF404
Function phosphatase activity
Related Protein SSH2B; PPM1F; ALP3; CTDSPLB; DUSP10; PTPRQ; CTDSPL2A; PTPREB; CDC14A; MTMR1A
Function phosphoprotein phosphatase activity
Related Protein DUSP28; PTPRK; PPM1H; SSH2; CTDNEP1B; PPP1CAA; PTPRJA; ACP2; PTPN23A; CTDSPL2B
Function poly(A) RNA binding
Related Protein RPSA; CDC5L; STRAP; PAN3; RPL24; SRP68; RPS27A; SRPR; RPL31; XRN2
Function protein N-terminus binding
Related Protein EXOC4; MEN1; SCT; NBN; ATM; PDLIM5; RPA3; ERCC3; PIAS3; PHB2
Function protein binding
Related Protein UBE2D2; ERO1L; MRPL15; TFAP2A; CSNK1A1; IL23R; NHEJ1; RMND5A; ZZZ3; PLEKHB2
Function protein kinase binding
Related Protein CRY1; LAX1; PDCD10; RPS3; PPP1R12C; PDGFRB; NR4A3; TEX14; ARHGEF7; SHC3
Function protein serine/threonine phosphatase activity
Related Protein PPM1LA; PPP2R5D; PPM1AA; PPEF2; CDKN3; PP2D1; DUSP23; PPM1AB; UBLCP1; PPP1R15B

Interacting Protein

PPP1CC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1CC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1CC.
TP53BP2; PPP1R2; ZFYVE9; URI1