• Official Full Name
  • superoxide dismutase 3, extracellular
  • Background
  • This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008]
  • Synonyms
  • SOD3; superoxide dismutase 3, extracellular; EC-SOD; extracellular superoxide dismutase [Cu-Zn];
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SOD3
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SOD3 protein, His-tagged
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human SOD3 protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SOD3, GST-tagged
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human SOD3
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SOD3 Protein
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Sod3 protein
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Sod3 protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SOD3 Protein
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Sod3 protein, His & T7-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SOD3 Protein, His-tagged
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit SOD3 protein, His & T7-tagged
Source (Host):Species:Human
Product nameRecombinant Human SOD3 293 Cell Lysate

Protein Function

SOD3 has several biochemical functions, for example, SMAD binding, chromatin binding, histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOD3 itself. We selected most functions SOD3 had, and list some proteins which have the same functions with SOD3. You can find most of the proteins on our site.
Related Protein
Function SMAD binding
Related Protein HMGA2; TGFBR1; SOD3; SKOR1; ACVR1B; ACVR1; FOXH1; COL1A2; FLNA; EID2
Function chromatin binding
Related Protein MED12; TAF2; CBFA2T3; WDHD1; SKOR2; PRKCBP1L; LDB1; ATAD2B; MB21D2; SP110
Function histone deacetylase binding
Related Protein HDAC9; SOD3; NUDT21; KAT2A; NKX2-5; NCOR1; BRMS1; TOP2A; HEY2; RAD9
Function transcription corepressor activity
Related Protein TGIF1; PAWR; RELB; SKOR1A; AES; NFIL3; NR0B2; ARHGAP35; SP100; BATF3

Interacting Protein

SOD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOD3.