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SOD3

  • Official Full Name

    superoxide dismutase 3, extracellular

  • Overview

    This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008]
  • Synonyms

    SOD3; superoxide dismutase 3, extracellular; EC-SOD; extracellular superoxide dismutase [Cu-Zn];

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rabbit
  • Rat
  • Rhesus Macaque
  • CHO
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SOD3-31476TH Recombinant Human SOD3 Wheat Germ N/A 100 amino acids
Human SOD3-1038H Recombinant Human SOD3 E.coli N/A
Human SOD3-2874H Recombinant Human SOD3, GST-tagged E.coli GST 1-240aa
Human SOD3-203H Recombinant Human SOD3 protein, GST-tagged Insect Cell GST
Human SOD3-108H Recombinant Human SOD3 protein, His-tagged E.coli His Trp19~Ala240
Human SOD3-1573HCL Recombinant Human SOD3 293 Cell Lysate HEK293 N/A
Human SOD3-2071H-B Recombinant Human SOD3 Protein Pre-coupled Magnetic Beads HEK293
Human SOD3-3516H Recombinant Human SOD3 protein E.coli N/A 19-240aa
Human SOD3-1235H Recombinant Human SOD3 Protein, His-tagged CHO N-His Trp19-Ala240
Human SOD3-5394H Recombinant Human SOD3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SOD3-586HFL Recombinant Full Length Human SOD3 Protein, C-Flag-tagged Mammalian cells Flag
Human SOD3-1234H Recombinant Human SOD3 Protein, His-tagged HEK293F N-His Trp19-Ala240
Human SOD3-2071H Recombinant Human SOD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SOD3-3182H Recombinant Human SOD3 Protein (Trp19-Ala240), His tagged E.coli His Trp19-Ala240
Mouse Sod3-16M Recombinant Mouse Sod3 protein E.coli N/A
Mouse Sod3-777M Recombinant Mouse Sod3 protein, His-tagged E.coli His Ser25~Thr251
Mouse SOD3-15751M Recombinant Mouse SOD3 Protein Mammalian Cell His
Mouse SOD3-8570M Recombinant Mouse SOD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SOD3-3374M Recombinant Mouse SOD3 protein, His-tagged HEK293 His Ser25~Thr251
Mouse Sod3-6042M Recombinant Mouse Sod3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SOD3-8570M-B Recombinant Mouse SOD3 Protein Pre-coupled Magnetic Beads HEK293
Rat Sod3-778R Recombinant Rat Sod3 protein, His & T7-tagged E.coli His/T7 Ser16~Thr244 (Accession # Q08420)
Rat SOD3-5668R Recombinant Rat SOD3 Protein Mammalian Cell His
Rat SOD3-5327R Recombinant Rat SOD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SOD3-5327R-B Recombinant Rat SOD3 Protein Pre-coupled Magnetic Beads HEK293
Rabbit SOD3-779R Recombinant Rabbit SOD3 protein, His & T7-tagged E.coli His/T7 Val25~Gly166
Rhesus Macaque SOD3-4407R Recombinant Rhesus monkey SOD3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SOD3-4223R Recombinant Rhesus Macaque SOD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SOD3-4223R-B Recombinant Rhesus Macaque SOD3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SOD3 Related Research Area

SOD3 involved in several pathways and played different roles in them. We selected most pathways SOD3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SOD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SOD3 has several biochemical functions, for example, SMAD binding, chromatin binding, histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOD3 itself. We selected most functions SOD3 had, and list some proteins which have the same functions with SOD3. You can find most of the proteins on our site.

Function Related Protein
SMAD bindingPRDM16;COL3A1;CTNNB1;PML;USP15;ACVR1B;SKOR1B;DAB2;FKBP1A
chromatin bindingTAF2;ARID3A;UBTFL;SKIL;HMGB1A;MED12;JARID2B;PRIMPOL;MB21D2
histone deacetylase bindingBCOR;SOD3;PHB;TOP2B;SFPQ;KLF4;DDX20;RUNX2;HOXA10
transcription corepressor activitySKI;MYBBP1A;ATF5;THRB;MSC;KCTD1;SSX5;PEX14;NEUROD2

SOD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOD3.

SGTA

  • Q&As
  • Reviews

Q&As (7)

Ask a question
What potential therapeutic applications arise from targeting SOD3 in oxidative stress-related conditions? 01/09/2022

Enhancing SOD3 activity could be a therapeutic strategy in treating oxidative stress-related diseases.

How do genetic variations in SOD3 affect its antioxidant function? 08/16/2021

Genetic mutations in SOD3 can impair its ability to scavenge free radicals, affecting its protective role.

How does SOD3 contribute to cellular protection against free radicals? 07/29/2020

It protects cells from oxidative damage by converting free radicals to less harmful substances.

What is the impact of altered SOD3 activity on aging and age-related diseases? 05/11/2020

Altered SOD3 activity is linked with accelerated aging and the development of age-related diseases.

How does SOD3 interact with other cellular antioxidants? 09/12/2019

SOD3 works alongside other antioxidants, contributing to the overall oxidative defense system.

What is the primary role of SOD3 in oxidative stress management? 11/03/2017

SOD3, a type of superoxide dismutase, is crucial for neutralizing superoxide radicals, reducing oxidative stress.

What role does SOD3 play in cardiovascular health? 05/05/2017

SOD3 is important for cardiovascular health, preventing oxidative damage in blood vessels.

Customer Reviews (3)

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Reviews
02/19/2023

    Trusted for results accuracy. A research necessity.

    06/22/2017

      Efficient and dependable. Accelerates our research progress.

      06/12/2017

        Enhances research credibility. Consistent and trustworthy.

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