SOD3

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SOD3

Official Full Name superoxide dismutase 3, extracellular
Background This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq, Jul 2008]
Synonyms SOD3; superoxide dismutase 3, extracellular; EC-SOD; extracellular superoxide dismutase [Cu-Zn];
    • Species :
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SOD3-5394H Recombinant Human SOD3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Sod3-6042M Recombinant Mouse Sod3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human SOD3-1038H Recombinant Human SOD3 E.coli N/A
    Human SOD3-108H Recombinant Human SOD3 protein, His-tagged E.coli His
    Human SOD3-1573HCL Recombinant Human SOD3 293 Cell Lysate HEK293 N/A
    Human SOD3-203H Recombinant Human SOD3 protein, GST-tagged Insect Cell GST
    Human SOD3-2874H Recombinant Human SOD3, GST-tagged E.coli GST
    Human SOD3-31476TH Recombinant Human SOD3 Wheat Germ N/A
    Mouse SOD3-15751M Recombinant Mouse SOD3 Protein Mammalian Cell His
    Mouse Sod3-16M Recombinant Mouse Sod3 protein E.coli N/A
    Mouse Sod3-777M Recombinant Mouse Sod3 protein, His-tagged E.coli His
    Rat SOD3-5668R Recombinant Rat SOD3 Protein Mammalian Cell His
    Rat Sod3-778R Recombinant Rat Sod3 protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque SOD3-4407R Recombinant Rhesus monkey SOD3 Protein, His-tagged Mammalian Cell His
    Rabbit SOD3-779R Recombinant Rabbit SOD3 protein, His & T7-tagged E.coli His/T7

    SOD3 involved in several pathways and played different roles in them. We selected most pathways SOD3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SOD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    SOD3 has several biochemical functions, for example, SMAD binding, chromatin binding, histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOD3 itself. We selected most functions SOD3 had, and list some proteins which have the same functions with SOD3. You can find most of the proteins on our site.

    Function Related Protein
    SMAD binding PRDM16; CREBBP; ACVR1B; MEF2A; PURB; EP300; HIPK2; SKOR1B; PURA; HMGA2
    chromatin binding SREBF1; ATF5; EGFR; PRKCBP1L; NONO; GLI3; NR5A1A; FABP1; GABPA; TFAP2A
    histone deacetylase binding CDC20; NCOR1; KAT2A; NR2E1; HES1; YWHAB; MEF2D; BRMS1LA; HDAC5; XBP1
    transcription corepressor activity RELB; DR1; SRSF2; TBL1X; RUNX1T1; ATF7IP; HDAC9; FEV; PROX1; SMYD1

    SOD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOD3.

    SGTA

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