• Official Full Name
  • Synaptophysin
  • Background
  • Defects in SYP are the cause of mental retardation X-linked SYP-related (MRXSYP) [MIM:300802]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.
  • Synonyms
  • Major synaptic vesicle protein P38; Syn p38; Synaptophysin; SYP; SYPH; SypI
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SYP, His-tagged
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human SYP
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SYP Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SYP Protein, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human SYP 293 Cell Lysate
Source (Host):Species:Human
Product nameAnti-Human SYP MAb Stable Cell Line-CHO
Source (Host):Species:Human
Product nameAnti-Human SYP F(ab) Stable Cell Line-CHO
Source (Host):Species:Human
Product nameAnti-Human SYP scFv Stable Cell Line-CHO

Involved Pathway

SYP involved in several pathways and played different roles in them. We selected most pathways SYP participated on our site, such as Synaptic Vesicle Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYP were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Synaptic Vesicle Pathway

Protein Function

SYP has several biochemical functions, for example, SH2 domain binding, cholesterol binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYP itself. We selected most functions SYP had, and list some proteins which have the same functions with SYP. You can find most of the proteins on our site.
Related Protein
Function SH2 domain binding
Related Protein SHCBP1; CTR9; ARHGAP5; LCK; LAX1; MS4A2; DLC1; DAG1; LAT2; SYP
Function cholesterol binding
Related Protein NPC2; STAR; SOAT1; CYP11A1; PTCH1; APOA5; ANXA6; APOEA; ERLIN1; CAV1
Function identical protein binding
Related Protein RAD51; MYD88; C1QL4; EWSR1; SORD; PFKM; GNPNAT1; YWHAZ; SF1; ITGB3
Function protein self-association
Related Protein VAMP2; AGTR1A; SLC2A1; CNTN2; LDB1; SHANK3; TRIM32; CCDC88C; TTN; TP53
Function transporter activity
Related Protein Abcb1b; SYPL1; SLC2A9L1; ABCC1; MUP20; VPS9D1; AP1B1; SLC5A6A; SLC4A1A; HIAT1

Interacting Protein

SYP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYP here. Most of them are supplied by our site. Hope this information will be useful for your research of SYP.

SYP Related Articles

Yang, JR; Liao, CH; et al. Transplantation of porcine embryonic stem cells and their derived neuronal progenitors in a spinal cord injury rat model. CYTOTHERAPY 15:201-208(2013).
Santos, LD; Torres, RM; et al. In-house ELISA method to analyze anti-Trypanosoma cruzi IgG reactivity for differential diagnosis and evaluation of Chagas disease morbidity. REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL 45:35-44(2012).