ANXA1 Protein


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Official Full Name annexin A1
Background Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity. [provided by RefSeq, Jul 2008]
Synonyms ANXA1; annexin A1; ANX1; LPC1; p35; annexin-1; calpactin-2; calpactin II; lipocortin I; chromobindin-9; annexin I (lipocortin I); phospholipase A2 inhibitory protein;
    • Species :
    • Chicken
    • Guinea pig
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Yeast
    • Tag :
    • C-Avi&6His
    • Flag
    • GST
    • His
    • His\Avi
    • S
    • MYC/DDK
    • N/A
    • N-His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANXA1-33H Active Recombinant Human ANXA1 protein, His-tagged E.coli His Inquiry
    Human ANXA1-26347TH Recombinant Human ANXA1, His-tagged E.coli His Inquiry
    Human ANXA1-26594TH Recombinant Human ANXA1 E.coli N/A Inquiry
    Human ANXA1-504H Recombinant Human annexin A1 E.coli N/A Inquiry
    Human ANXA1-5257H Recombinant Human Annexin A1, His-tagged E.coli His Inquiry
    Human ANXA1-5277H Recombinant Human Annexin A1, T7-tagged E.coli T7 Inquiry
    Human ANXA1-627H Recombinant Human ANXA1 protein, GST-tagged Wheat Germ GST Inquiry
    Human ANXA1-9159H Recombinant Human ANXA1 protein E.coli His Inquiry
    Mouse Anxa1-1122M Recombinant Mouse Anxa1 Protein, His-tagged E.coli His Inquiry
    Mouse ANXA1-1710M Recombinant Mouse ANXA1 Protein Mammalian Cell His Inquiry
    Mouse Anxa1-1712M Recombinant Mouse Anxa1 protein, His/S-tagged E.coli His/S Inquiry
    Rat Anxa1-1345R Recombinant Rat Anxa1 protein, His & S-tagged E.coli His/S Inquiry
    Rat ANXA1-688R Recombinant Rat ANXA1 Protein Mammalian Cell His Inquiry
    Rabbit ANXA1-1346R Recombinant Rabbit ANXA1 protein, His & S-tagged E.coli His/S Inquiry
    Rabbit ANXA1-1347R Recombinant Rabbit ANXA1 protein, His-tagged E.coli His Inquiry
    Chicken ANXA1-7094C Recombinant Chicken ANXA1 Mammalian Cell His Inquiry
    Pig ANXA1-133P Recombinant Pig ANXA1 Protein, His-tagged E.coli His Inquiry
    Pig ANXA1-1344P Recombinant Pig ANXA1 protein, His & S-tagged E.coli His/S Inquiry
    Guinea pig ANXA1-3491C Recombinant Cavia cutleri (Guinea pig) ANXA1, His-tagged E.Coli or Yeast His Inquiry
    Guinea pig ANXA1-3492C Recombinant Cavia (Guinea pig) ANXA1, His-tagged, S tagged E.coli His/S Inquiry
    Human ANXA1-8839HCL Recombinant Human ANXA1 293 Cell Lysate HEK293 N/A Inquiry
    Human ANXA1-1039HF Recombinant Full Length Human ANXA1 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Human ANXA1-160HFL Recombinant Full Length Human ANXA1 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Rat Anxa1-161R Recombinant Rat Anxa1 Protein, His-tagged E.coli N-His Inquiry
    Human ANXA1-213H Recombinant Human ANXA1 Protein, His\Avi-tagged E.coli His\Avi Inquiry
    Human ANXA1-40H Recombinant Human ANXA1 Protein, C-Avi&6His tagged, Biotinylated E.coli C-Avi&6His Inquiry
    Human ANXA1-001H Recombinant Human ANXA1 Protein, His-tagged E.coli His Inquiry
    Human ANXA1-1725H Recombinant Human ANXA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human ANXA1-26348TH Recombinant Human ANXA1 N/A Inquiry
    Mouse Anxa1-1334M Recombinant Mouse Anxa1 Protein, MYC/DDK-tagged HEK293T MYC/DDK Inquiry
    Mouse Anxa1-7269M Recombinant Mouse Anxa1 Protein, His-tagged E.coli His Inquiry
    Mouse Anxa1-1713M Recombinant Mouse Anxa1 Protein, His-tagged E.coli His Inquiry
    Mouse Anxa1-1714M Recombinant Mouse Anxa1 Protein, His-tagged Yeast His Inquiry

    ANXA1 involved in several pathways and played different roles in them. We selected most pathways ANXA1 participated on our site, such as Class A/1 (Rhodopsin-like receptors), Formyl peptide receptors bind formyl peptides and many other ligands, G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors) RLN2; CHRM4; CCR5; S1PR5B; PENKA; HCAR1-2; NTS; UTS2; GPR31B; GPR132
    Formyl peptide receptors bind formyl peptides and many other ligands HEBP1; FPR-RS4; FPR-RS6; ANXA1; FPR-RS3
    G alpha (i) signalling events S1PR5B; CHRM2; SSTR2; CXCL13; PNOC; FPR-RS6; SST1.1; CCL35.2; GPR17; RLN3
    G alpha (q) signalling events CHRM5; PROK2; LPAR5A; OPN4A; GPR68; LTB4R; GRP; OPN4B; NPSR1; OPN4
    GPCR downstream signaling RGR; TAS2R7; RGS19; GPR17; CRHR2; PROK2; NMUR1; NPFFR2; GNA13; ADORA2B
    GPCR ligand binding OXGR1A.1; GPR55A; GCGB; SSTR3; EDN1; OPN1MW2; ADM; PYY; DRD4; LPAR2B
    Gastrin-CREB signalling pathway via PKC and MAPK OXTRL; NPSR1; TRIO; NMUR1; PMCH; FPR-RS4; OPN4.1; ANXA1A; ANXA1; QRFP
    Integrated Breast Cancer Pathway DAG1; AHR; DHTKD1; USP38; APOBEC3G; C21orf7; PLK3; EDAR; USP16; CCNB1IP1

    ANXA1 has several biochemical functions, for example, annealing helicase activity, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA1 itself. We selected most functions ANXA1 had, and list some proteins which have the same functions with ANXA1. You can find most of the proteins on our site.

    Function Related Protein
    annealing helicase activity RECQL4; BLM; SMARCAL1; RAD54L; ZRANB3; RECQL; ANXA1
    calcium ion binding NOX5; RHOT1A; CALM2; CIB4; SYT11; PCDH2G28; EFCAB2; PCDHB14; MYL7; NCALDA
    calcium-dependent phospholipid binding RPH3A; PLA2G4B; ANXA3A; SYTL2; SYT15; SYTL3; TC2N; SYT7B; SYTL4; SYTL1
    calcium-dependent protein binding RAC3; MBL2; A2M; VPS37C; SYT1; STMN2; ANXA4; MASP1; S100A4; MYO1D
    double-stranded DNA-dependent ATPase activity ANXA1
    helicase activity ZRANB3; DHX58; CHD6; TDRD9; MCM8; DDX58; EIF4A1B; IFIH1; SMARCA5; HELZ2
    phospholipase A2 inhibitor activity CC10; ANXA1; ANXA2; ANXA3
    phospholipid binding PAFAH2; PICALMA; PLA2G4C; NR5A1; GLTPD1; BAD; SNCA; NOXO1; LRBA; BAIAP2L2
    protein binding RBP4; S100A4; CHD2; NVL; STAG3; DRD4; TMEM8B; NUDT4; GRAP; ZNF436
    protein binding, bridging NEFH; ADAP2; FGB; NEFL; COL8A2; FSCN2; STUB1; FLRT1; TCAP; FSCN1
    protein homodimerization activity ENO2; ENPP1; UGT1A7; CASQ2; CDSN; B4GALT1; BAXB; APOE; ABCD3; NKX2
    receptor binding CAV1; HAMP; FGF11; NPPC; EFNA1; RSPO2; IDUA; WNT2BA; Ren1; HLA-F
    single-stranded DNA binding MEIOB; SSBP3A; POLR2G; RAD23A; NABP2; XRCC3; RAD51; RAD51C; MCM7; HNRNPK
    single-stranded RNA binding AGO3; ENDOV; DDX58; POLR2G; CBX8; LONP1; AGO1; HNRNPF; TLR7; RBMX
    structural molecule activity KRT27; CSTA; MAP2; LCE3D; IFFO2; CYT1; SNTB1; KRT31; CLDNB; JUP

    ANXA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA1.


    Belvedere, R; Bizzarro, V; et al. Role of intracellular and extracellular annexin A1 in migration and invasion of human pancreatic carcinoma cells. BMC CANCER 14:-(2014).
    Wang, WL; Guan, SL; et al. Detection of circulating antibodies to linear peptide antigens derived from ANXA1 and DDX53 in lung cancer. TUMOR BIOLOGY 35:4901-4905(2014).

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