Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512

Recombinant Human CA7

Cat.No. : CA7-51H
Product Overview : Recombinant Human Carbonic Anhydrase 7/CA7 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala264) of Human CA7.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore, Alpha-carbonic anhydrase is associated with many biological processes, including calcification, respiration, bone resorption, acid-base balance and the formation of aqueous humor. CA7 is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine, but it is inhibited coumarins, sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet.
Source : E. coli
Species : Human
Form : Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0
AA Sequence : MTGHHGWGYGQDDGPSHWHKLYPIA QGDRQSPINIISSQAVYSPSLQPLE LSYEACMSLSITNNG HSVQVDFNDSDDRTVVTGGPLEGPY RLKQFHFHWGKKHDVGSEHTVDGKS FPSELHLVHWNAKKY STFGEAASAPDGLAVVGVFLETGDE HPSMNRLTDALYMVRFKGTKAQFSC FNPKCLLPASRHYWT YPGSLTTPPLSESVTWIVLREPICI SERQMGKFRSLLFTSEDDERIHMVN NFRPPQPLKGRVVKA SFRALEHHHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Storage : Store at Please minimize freeze-thaw cycles.
Gene Name : CA7 carbonic anhydrase VII [ Homo sapiens ]
Official Symbol : CA7
Synonyms : CA7; carbonic anhydrase VII; carbonic anhydrase 7; CA-VII; carbonic dehydratase VII; carbonate dehydratase VII; CAVII;
Gene ID : 766
mRNA Refseq : NM_001014435
Protein Refseq : NP_001014435
MIM : 114770
UniProt ID : P43166
Chromosome Location : 16q22.1
Function : carbonate dehydratase activity; lyase activity; metal ion binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
What distinguishes the enzymatic function of CA7 from other carbonic anhydrase family members? 12/02/2022

CA7 facilitates the reversible hydration of carbon dioxide, but its specific kinetics might differ from other isoforms.

How does CA7 contribute to cellular pH balance and metabolism? 11/08/2020

CA7 aids in CO2 transport and pH regulation, playing a crucial role in metabolic processes.

Have any diseases or conditions been associated with aberrant CA7 expression or activity? 12/26/2019

Dysregulation or mutations in CA7 might influence metabolic balance in tissues, potentially impacting conditions related to liver function or metabolism.

Are there compounds known to specifically inhibit CA7 activity? 12/13/2018

While some general carbonic anhydrase inhibitors might affect CA7, isoform-specific inhibitors would require further research.

In which specific human tissues is CA7 expression most prevalent? 04/28/2018

CA7 is primarily expressed in the liver, among other tissues.

What post-translational modifications are characteristic of CA7? 01/10/2018

Potential modifications like phosphorylation or acetylation can be identified using techniques like mass spectrometry.

Are there any genetic mutations in the CA7 gene known to influence its enzymatic functionality? 03/06/2017

Specific mutations could alter CA7's enzyme kinetics or stability, requiring in vitro functional assays for verification.

Customer Reviews (3)

Write a review
Reviews
09/20/2022

    Expertise in protein analysis, accelerates our research.

    07/13/2021

      Affordable pricing, excellent value for research budgets.

      05/22/2021

        Invaluable for our protein-related discoveries and innovations.

        Ask a Question for All CA7 Products

        Required fields are marked with *

        My Review for All CA7 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends