Recombinant Human CA7 Protein, GST-Tagged

Cat.No. : CA7-0247H
Product Overview : Human CA7 full-length ORF (AAH33865, 1 a.a. - 264 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 54.67 kDa
AA Sequence : MTGHHGWGYGQDDGPSHWHKLYPIA QGDRQSPINIISSQAVYSPSLQPLE LSYEACMSLSITNNGHSVQVDFNDS DDRTVVTGGPLEGPYRLKQFHFHWG KKHDVGSEHTVDGKSFPSELHLVHW NAKKYSTFGEAASAPDGLAVVGVFL ETGDEHPSMNRLTDALYMVRFKGTK AQFSCFNPKCLLPASRHYWTYPGSL TTPPLSESVTWIVLREPICISERQM GKFRSLLFTSEDDERIHMVNNFRPP QPLKGRVVKASFRA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
FACS: 12.5% SDS-PAGE Stained with Coomassie Blue.
Gene Name : CA7 carbonic anhydrase VII [ Homo sapiens ]
Official Symbol : CA7
Synonyms : CA7; carbonic anhydrase VII; carbonic anhydrase 7; CA-VII; carbonic dehydratase VII; carbonate dehydratase VII; CAVII;
Gene ID : 766
mRNA Refseq : NM_001014435
Protein Refseq : NP_001014435
MIM : 114770
UniProt ID : P43166

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What distinguishes the enzymatic function of CA7 from other carbonic anhydrase family members? 12/02/2022

CA7 facilitates the reversible hydration of carbon dioxide, but its specific kinetics might differ from other isoforms.

How does CA7 contribute to cellular pH balance and metabolism? 11/08/2020

CA7 aids in CO2 transport and pH regulation, playing a crucial role in metabolic processes.

Have any diseases or conditions been associated with aberrant CA7 expression or activity? 12/26/2019

Dysregulation or mutations in CA7 might influence metabolic balance in tissues, potentially impacting conditions related to liver function or metabolism.

Are there compounds known to specifically inhibit CA7 activity? 12/13/2018

While some general carbonic anhydrase inhibitors might affect CA7, isoform-specific inhibitors would require further research.

In which specific human tissues is CA7 expression most prevalent? 04/28/2018

CA7 is primarily expressed in the liver, among other tissues.

What post-translational modifications are characteristic of CA7? 01/10/2018

Potential modifications like phosphorylation or acetylation can be identified using techniques like mass spectrometry.

Are there any genetic mutations in the CA7 gene known to influence its enzymatic functionality? 03/06/2017

Specific mutations could alter CA7's enzyme kinetics or stability, requiring in vitro functional assays for verification.

Customer Reviews (3)

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Reviews
09/20/2022

    Expertise in protein analysis, accelerates our research.

    07/13/2021

      Affordable pricing, excellent value for research budgets.

      05/22/2021

        Invaluable for our protein-related discoveries and innovations.

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