CD53
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Official Full Name
Cd53 molecule
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Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family.;Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains.;The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,;growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It;contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to;play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated;with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple;transcript variants encoding the same protein. -
Synonyms
CD53; Cd53 molecule; leukocyte surface antigen CD53; CD53 antigen; Leukocyte antigen (Ox-44); leukocyte antigen MRC OX-44; cell surface glycoprotein CD53; OX44; Ox-44; RATOX44;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Cynomolgus
- Cynomolgus Monkey
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Human Cells
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Protein Conjugation
- Wheat Germ
- Fc
- GST
- His
- Avi
- mFc
- Myc
- DDK
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CD53-0832H | Recombinant Human CD53 Protein | Wheat Germ | Non |
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| Human | CD53-0833H | Recombinant Human CD53 Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CD53-3094H | Recombinant Human CD53 Protein, MYC/DDK-tagged | HEK293 | Myc&DDK |
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| Human | CD53-151H | Recombinant Human CD53 Protein, His-tagged | Human Cells | His |
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| Human | CD53-2785H | Recombinant Human CD53 Protein, His-tagged, OVA Conjugated | Protein Conjugation | His | Leu142-Pro157 |
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| Human | CD53-4283H | Recombinant Human CD53 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc&DDK |
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| Human | CD53-503H | Recombinant Human CD53 Protein, His&GST-tagged | E.coli | His&GST | Glu107-Leu219 |
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| Human | CD53-3001HF | Recombinant Full Length Human CD53 Protein | In Vitro Cell Free System | 134 amino acids |
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| Human | CD53-5358H | Recombinant Human CD53 Protein (Glu107-Asn181), C-His tagged | Mammalian cells | His | Glu107-Asn181 |
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| Human | CD53-3002HF | Recombinant Full Length Human CD53 Protein, GST-tagged | In Vitro Cell Free System | GST | 219 amino acids |
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| Mouse | CD53-158M | Recombinant Mouse Cd53, His tagged | Human Cell | Fc | Glu107-Asn181 |
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| Mouse | CD53-808MCL | Recombinant Mouse CD53 cell lysate | Human Cell | Non | 107-181 |
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| Mouse | Cd53-844M | Recombinant Mouse Cd53 Protein, MYC/DDK-tagged | HEK293T | Myc&DDK |
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| Mouse | CD53-2242M | Recombinant Mouse CD53 protein, His-tagged | HEK293 | His | Glu107-Asn181 |
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| Rat | CD53-1259R | Recombinant Rat CD53 Protein | Mammalian Cell | His |
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| Rat | CD53-917R-B | Recombinant Rat CD53 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | CD53-917R | Recombinant Rat CD53 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Bos taurus (Bovine) | RFL32283BF | Recombinant Full Length Bovine Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged | E.coli expression system | His | Full Length (1-219) |
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| Cynomolgus | CD53-2387C | Recombinant Cynomolgus CD53 protein(Glu107-Asn181), mFc-tagged | HEK293 | mFc | Glu107-Asn181 |
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| Cynomolgus | CD53-1304C | Recombinant Cynomolgus CD53 protein, His-tagged | HEK293 | His | Glu107-Asn181 |
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| Cynomolgus Monkey | CD58-100C | Rcombinant Cynomolgus CD58, His-tagged | Human Cell | His | Met1-Arg215 |
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| Cynomolgus Monkey | CD53-99C | Recombinant Cynomolgus CD53, His tagged | Human Cell | Non | Glu107-Asn181 |
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| Cynomolgus Monkey | CD53-98C | Recombinant Cynomolgus CD53, Fc tagged | Human Cell | His&Fc | Glu107-Asn181 |
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| Cynomolgus Monkey | CD53-1018CCL | Recombinant Cynomolgus CD53 cell lysate | Human Cell | Non | 107-181 |
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| Cynomolgus Monkey | CD53-1122CCL | Recombinant Cynomolgus CD53 cell lysate | Human Cell | Non | 107-181 |
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| Homo sapiens (Human) | RFL26052HF | Recombinant Full Length Human Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged | E.coli expression system | His | Full Length (1-219) |
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| Mus musculus (Mouse) | RFL20079MF | Recombinant Full Length Mouse Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-219) |
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| Rattus norvegicus (Rat) | RFL9289RF | Recombinant Full Length Rat Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-219) |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
CD53 involved in several pathways and played different roles in them. We selected most pathways CD53 participated on our site, such as IL-2 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD53 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| IL-2 Signaling Pathway | SHB;CISH;CD53;NMI;ITM2BA |
CD53 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CD53 itself. We selected most functions CD53 had, and list some proteins which have the same functions with CD53. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
CD53 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD53 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD53.
Research Area
Related articles
Todros-Dawda, I; Kveberg, L; et al. The Tetraspanin CD53 Modulates Responses from Activating NK Cell Receptors, Promoting LFA-1 Activation and Dampening NK Cell Effector Functions. PLOS ONE 9:-(2014).
Ruiz-Mateos, E; Pelchen-Matthews, A; et al. CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages. JOURNAL OF VIROLOGY 82:4751-4761(2008).
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