CD53

  • Official Full Name

    Cd53 molecule

  • Overview

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family.;Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains.;The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,;growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It;contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to;play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated;with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple;transcript variants encoding the same protein.
  • Synonyms

    CD53; Cd53 molecule; leukocyte surface antigen CD53; CD53 antigen; Leukocyte antigen (Ox-44); leukocyte antigen MRC OX-44; cell surface glycoprotein CD53; OX44; Ox-44; RATOX44;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Cynomolgus
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Protein Conjugation
  • Wheat Germ
  • C
  • His
  • Fc
  • Fc|His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD53-0832H Recombinant Human CD53 Protein Wheat Germ N/A
Human CD53-0833H Recombinant Human CD53 Protein, GST-Tagged Wheat Germ GST
Human CD53-3094H Recombinant Human CD53 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD53-151H Recombinant Human CD53 Protein, His-tagged Human Cells His
Human CD53-2785H Recombinant Human CD53 Protein, His-tagged, OVA Conjugated Protein Conjugation N-His
Human CD53-4283H Recombinant Human CD53 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD53-503H Recombinant Human CD53 Protein, His&GST-tagged E.coli N-His&GST
Human CD53-3001HF Recombinant Full Length Human CD53 Protein In Vitro Cell Free System
Human CD53-5358H Recombinant Human CD53 Protein (Glu107-Asn181), C-His tagged Mammalian cells C-His
Human CD53-3002HF Recombinant Full Length Human CD53 Protein, GST-tagged In Vitro Cell Free System GST
Mouse CD53-158M Recombinant Mouse Cd53, His tagged Human Cell Fc
Mouse CD53-808MCL Recombinant Mouse CD53 cell lysate Human Cell N/A
Mouse Cd53-844M Recombinant Mouse Cd53 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CD53-2242M Recombinant Mouse CD53 protein, His-tagged HEK293 His
Rat CD53-1259R Recombinant Rat CD53 Protein Mammalian Cell His
Rat CD53-917R-B Recombinant Rat CD53 Protein Pre-coupled Magnetic Beads HEK293
Rat CD53-917R Recombinant Rat CD53 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL32283BF Recombinant Full Length Bovine Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged E.coli expression system His
Cynomolgus CD53-1304C Recombinant Cynomolgus CD53 protein, His-tagged HEK293 His
Cynomolgus Monkey CD58-100C Rcombinant Cynomolgus CD58, His-tagged Human Cell His
Cynomolgus Monkey CD53-99C Recombinant Cynomolgus CD53, His tagged Human Cell N/A
Cynomolgus Monkey CD53-98C Recombinant Cynomolgus CD53, Fc tagged Human Cell Fc/His
Cynomolgus Monkey CD53-1018CCL Recombinant Cynomolgus CD53 cell lysate Human Cell N/A
Cynomolgus Monkey CD53-1122CCL Recombinant Cynomolgus CD53 cell lysate Human Cell N/A
Homo sapiens (Human) RFL26052HF Recombinant Full Length Human Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL20079MF Recombinant Full Length Mouse Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged E.coli expression system His
Rattus norvegicus (Rat) RFL9289RF Recombinant Full Length Rat Leukocyte Surface Antigen Cd53(Cd53) Protein, His-Tagged E.coli expression system His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CD53 Related Articles
  • CD53 Related Research Area

CD53 involved in several pathways and played different roles in them. We selected most pathways CD53 participated on our site, such as IL-2 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD53 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
IL-2 Signaling PathwayCD53;CISH;ITM2BA;SHB;NMI

CD53 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CD53 itself. We selected most functions CD53 had, and list some proteins which have the same functions with CD53. You can find most of the proteins on our site.

Function Related Protein

CD53 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD53 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD53.

Todros-Dawda, I; Kveberg, L; et al. The Tetraspanin CD53 Modulates Responses from Activating NK Cell Receptors, Promoting LFA-1 Activation and Dampening NK Cell Effector Functions. PLOS ONE 9:-(2014).
Ruiz-Mateos, E; Pelchen-Matthews, A; et al. CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages. JOURNAL OF VIROLOGY 82:4751-4761(2008).
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