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Recombinant Human CD53 Protein, His-tagged

Cat.No. : CD53-151H
Product Overview : Recombinant Human CD53 molecule(CD53), transcript variant 2(NM_000560), with a His tag, was expressed in human cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.
Source : Human Cells
Species : Human
Tag : His
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.141, without any preservatives.
Molecular Mass : 24.2 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : CD53 CD53 molecule [ Homo sapiens ]
Official Symbol : CD53
Synonyms : CD53; CD53 molecule; CD53 antigen , MOX44; leukocyte surface antigen CD53; TSPAN25; tspan-25; CD53 antigen; tetraspanin-25; CD53 glycoprotein; cell surface antigen; CD53 tetraspan antigen; transmembrane glycoprotein; cell surface glycoprotein CD53; antigen MOX44 identified by monoclonal MRC-OX44; MOX44;
Gene ID : 963
mRNA Refseq : NM_000560
Protein Refseq : NP_000551
MIM : 151525
UniProt ID : P19397

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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