CNR1

  • Official Full Name

    Cnr1 cannabinoid receptor 1 (brain)

  • Synonyms

    CNR1; cannabinoid receptor 1 (brain); cannabinoid receptor 1; brain-type cannabinoid receptor; striatal cannabinoid receptor type 1 protein; CB1; CB-R; CB1R;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Felis catus (Cat) (Felis silvestris catus)
  • Homo sapiens (Human)
  • Human
  • Macaca mulatta (Rhesus macaque)
  • Mus musculus (Mouse)
  • Pan troglodytes (Chimpanzee)
  • Pelophylax esculentus (Edible frog) (Rana esculenta)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Taeniopygia guttata (Zebra finch) (Poephila guttata)
  • Taricha granulosa (Roughskin newt)
  • Xenopus laevis (African clawed frog)
  • Zea mays (Maize)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • In vitro E. coli expression system
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CNR1-1597H Recombinant Human CNR1 Protein, GST-tagged Wheat Germ GST
Human CNR1-27264TH Recombinant Human CNR1 Wheat Germ N/A 110 amino acids
Human CNR1-7395HCL Recombinant Human CNR1 293 Cell Lysate HEK293 N/A
Human CNR1-2711H Recombinant Human CNR1 Protein, His-tagged E.coli His
Human CNR1-1153HFL Recombinant Human CNR1 protein, His&Flag-tagged HEK293 His&Flag 1-472 aa
Human CNR1-27H Active Recombinant Human CNR1 Full Length Transmembrane protein(VLPs) HEK293 N/A Met 1 - Lys 472
Human CNR1-1958HF Recombinant Full Length Human CNR1 Protein, GST-tagged In Vitro Cell Free System GST 472 amino acids
Human CNR1-718H Active Recombinant Human CNR1 Full Length Transmembrane protein, His-tagged HEK293 His 1-472aa
Rat Cnr1-8166R Recombinant Rat Cnr1 protein, His & T7-tagged E.coli His/T7 Met1~Gln117 (Accession# P20272)
Rat CNR1-1498R Recombinant Rat Cnr1 Protein E.coli
Rat CNR1-1094R Recombinant Rat CNR1 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-473aa
Felis catus (Cat) (Felis silvestris catus) RFL32060FF Recombinant Full Length Cat Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-472)
Homo sapiens (Human) RFL31979HF Recombinant Full Length Human Cannabinoid Receptor 1(Cnr1)-Vlps (Active) Protein, His-Tagged E.coli expression system His Full Length (1-472aa)
Homo sapiens (Human) RFL9726HF Recombinant Full Length Human Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-472)
Macaca mulatta (Rhesus macaque) RFL26027MF Recombinant Full Length Macaca Mulatta Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-472)
Mus musculus (Mouse) RFL8888MF Recombinant Full Length Mouse Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-473)
Pan troglodytes (Chimpanzee) RFL29964PF Recombinant Full Length Pan Troglodytes Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-472)
Pelophylax esculentus (Edible frog) (Rana esculenta) RFL6840PF Recombinant Full Length Rana Esculenta Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-462)
Rattus norvegicus (Rat) RFL35759RF Recombinant Full Length Rat Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-473)
Rhesus Macaque CNR1-947R Recombinant Rhesus monkey CNR1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CNR1-772R Recombinant Rhesus Macaque CNR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CNR1-772R-B Recombinant Rhesus Macaque CNR1 Protein Pre-coupled Magnetic Beads HEK293
Taeniopygia guttata (Zebra finch) (Poephila guttata) RFL28531TF Recombinant Full Length Taeniopygia Guttata Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-473)
Taricha granulosa (Roughskin newt) RFL21126TF Recombinant Full Length Taricha Granulosa Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-473)
Xenopus laevis (African clawed frog) RFL10383XF Recombinant Full Length Xenopus Laevis Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-470)
Zea mays (Maize) RFL2081ZF Recombinant Full Length Zea Mays Cell Number Regulator 1(Cnr1) Protein, His-Tagged E.coli expression system His Full Length (1-191)
Zebrafish CNR1-12086Z Recombinant Zebrafish CNR1 Mammalian Cell His
Chicken CNR1-3314C Recombinant Chicken CNR1 Mammalian Cell His
Kit-1180 CNR1 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1051 Cell Transformation Assay Kit (Colorimetric) N/A
Kit-1026 Albumin (BCG) Assay Kit (Colorimetric) N/A
Kit-1179 cAMP CNR1 (CB1) CHO-K1 GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CNR1 involved in several pathways and played different roles in them. We selected most pathways CNR1 participated on our site, such as BDNF signaling pathway, Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
BDNF signaling pathwayBCL2L11;DOK5;DPYSL2;KCNN2;YBX1;EGR1;SIRPA;IGF2BP1;FRS2
Class A/1 (Rhodopsin-like receptors)CCR6;EDN3;GPR68;OXTRL;CCBP2;KEL;CXCR7B;NMU;NMS
G alpha (i) signalling eventsRGS11;GAL;GPR17;PENKA;PPY;CNR2;RHOL;LPAR2B;CCR6
GPCR downstream signalingCXCR7B;GNA13B;ARHGEF25;ARHGAP4A;CNR1;ADCYAP1;QRFP;GPR68;CCR1
GPCR ligand bindingPROKR1;CXCR7B;GAL;S1PR5B;PTHRP2;GPR55A;LPAR1;CD97;ACKR4
GPCRs, Class A Rhodopsin-likeOPN1LW;GPR4;OPN4;FPR-RS4;GPR37L1;GPR75;CCR7;OPN3;OPN1MW
N-cadherin signaling eventsCNR1;GAP43
Neuroactive ligand-receptor interactionPRLHR;FPR1;KISS1RB;RXFP1;CHRM5B;PTGER1C;TACR1;GRIN2BB;NPY1R

CNR1 has several biochemical functions, for example, cannabinoid receptor activity, drug binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNR1 itself. We selected most functions CNR1 had, and list some proteins which have the same functions with CNR1. You can find most of the proteins on our site.

Function Related Protein
cannabinoid receptor activityCNR2;CNR1;GPR55
drug bindingABP1;HTR1B;GRIK1;PIGC;CYP2D6;HTR2C;UGT1A7;PPP3CA;PYGL

CNR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CNR1.

ADORA2A; win 55212-2

Gene Family

GPCRs

Research Area

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
08/18/2022

    DNA binding ability is strong, and it performs well in related experiments.

    04/24/2022

      The immunogenicity is very weak, does not cause an immune response, and has a high safety profile.

      04/09/2022

        CNR1 has a long shelf life and good stability, which is convenient for the continuity of subsequent experiments.

        Q&As (6)

        Ask a question
        What are the mechanisms of action of CNR1 receptor agonists and antagonists? 07/17/2022

        The protein receptor agonists can bind to receptors, activate receptors, and promote their signal transduction, resulting in physiological effects. CNR1 receptor antagonists, on the other hand, can bind to the receptor and prevent endocannabinoids from binding to the receptor, thereby inhibiting its signal transduction.

        What are the types of CNR1 mutations? 06/10/2021

        There are many types of mutations in the CNR1 gene, including single nucleotide substitution, insertion, or deletion. These mutations may cause structural and functional changes in the CNR1 receptor, affecting its binding and signal transduction to endocannabinoids.

        What role does the CNR1 receptor play in neuronal connections and neural circuits? 03/10/2021

        CNR1 receptors play an important role in neuronal connections and neural circuits. It is involved in the growth, differentiation, and synapse formation of neurons, as well as in the regulation of neural circuits and signal transduction.

        How about the potential applications of the CNR1 receptor in drug development? 08/22/2020

        CNR1 receptors have potential applications in drug development. Some studies have shown that CNR1 receptor agonists or antagonists can be used to treat neurological disorders such as pain, depression, and anxiety.

        Does the CNR1 gene polymorphism affect individual differences? 08/11/2020

        Polymorphisms in the CNR1 gene may cause differences in individual responses to medications. Some polymorphisms may increase an individual's sensitivity or tolerance to medications, which can affect the efficacy and safety of medications.

        Do environmental factors influence CNR1 gene expression? 12/01/2019

        For example, some drugs, toxins, or stressors may affect the expression level of the CNR1 gene, thus affecting its function and signal transduction processes.

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