COX6B1 involved in several pathways and played different roles in them. We selected most pathways COX6B1 participated on our site, such as Alzheimers disease, Cardiac muscle contraction, Electron Transport Chain, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX6B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Alzheimers disease |
NDUFB9; NDUFA7; APAF1; NDUFC2-KCTD14; NDUFB8; BID; MME; ATP2A2; TNF; BACE2 |
| Cardiac muscle contraction |
TPM2; COX5AA; UQCR11; ATP1B3B; ACTC1B; COX7C; TPM4A; CACNB1; COX5B; CACNG4 |
| Electron Transport Chain |
COX6C; ATP5S; COX11; SCO1; SURF1; COX15; UCP2; NDUFS7; COX4I1; COX6A1 |
| Gene Expression |
ZNF839; ZNF192; GTF3AB; HBXIP; CSTF2; ZNF550; DNMT1; DCP2; ZNF311; ZNF697 |
| Generic Transcription Pathway |
ZNF74; HELZ2; NRBP1; ZNF498; ZNF317; SURF1; PRDM7; NR2F1A; ZNF157; Txn1 |
| Huntingtons disease |
ITPR1; NDUFV1; NDUFS6; COX7A2L; DNAIC2; DNAHC8; UQCR11; VDAC2; NDUFA7; ATP5B |
| Metabolic pathways |
ST6GALNAC4; glpK; SEPHS2; GLULA; AANAT1; UQCRC1; PGK1; SMS; GLDC; CYP2C39 |
| Metabolism |
CYP2U1; CHKB; DUT; DECR1; FABP9; MPC1; HIBADH; PTGDSA; SLC25A20; NDUFAF5 |
COX6B1 has several biochemical functions, for example, cytochrome-c oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COX6B1 itself. We selected most functions COX6B1 had, and list some proteins which have the same functions with COX6B1. You can find most of the proteins on our site.
| Function |
Related Protein |
| cytochrome-c oxidase activity |
COX7C; COA6; COX6A1; COX7A2L; COX6B2; COX7A1; COX7A3; COX15; COX7B; COX11 |
COX6B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX6B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COX6B1.
env; 40038273; MT-CO2; VPS26A; Zbtb7a; Cdc6; YEATS4; XRCC5; Rab5c; HTT; RAB5C; POLR2G; TMEM132A; Ankfy1; Sidt2; YIPF5; TIMMDC1; VAPA
Abdulhag, UN; Soiferman, D; et al. Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy. EUROPEAN JOURNAL OF HUMAN GENETICS 23:159-164(2015).
Lim, J; Liu, ZB; et al. Dual Mode Action of Mangiferin in Mouse Liver under High Fat Diet. PLOS ONE 9:-(2014).
