hdac9
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  • Official Full Name
  • histone deacetylase 9
  • Background
  • Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
  • Synonyms
  • HDAC9; histone deacetylase 9; HD7; HDAC; HDAC7B; KIAA0744; MITR; histone deacetylase 7B; histone deacetylase 4/5-related protein; MEF-2 interacting transcription repressor (MITR) protein; HD9; HD7b; HDRP; HDAC7; HDAC9B; HDAC9FL; DKFZp779K1053
Cat.#:HDAC9-1303HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HDAC9 Protein (814-1011 aa), His-tagged
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Cat.#:HDAC9-4652HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HDAC9 Protein, GST-tagged
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Cat.#:HDAC9-1596HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Histone Deacetylase 9, His-tagged
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Cat.#:HDAC9-1372HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HDAC9 protein, His & T7-tagged
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Cat.#:HDAC9-28444THTag:His
Source (Host):Species:Human
Product nameRecombinant Human HDAC9, His-tagged
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Cat.#:HDAC9-798HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human HDAC9
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Cat.#:HDAC9-2665CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HDAC9
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Cat.#:HDAC9-400HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Histone Deacetylase 9, GST-tagged
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Cat.#:HDAC9-5601HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human HDAC9 293 Cell Lysate
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Cat.#:Kit-1745Tag:N/A
Source (Host):Species:
Product nameHDAC9 Fluorogenic Assay Kit
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Involved Pathway

HDAC9 involved in several pathways and played different roles in them. We selected most pathways HDAC9 participated on our site, such as Alcoholism, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HDAC9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alcoholism
HIST2H3C; GNG12; HIST1H3F; HIST1H2AL; HIST1H2AA; H3F3A; GNAS; CAMKK2; GM6026; HIST1H2BL
Viral carcinogenesis
TBP; POLB; CDC20; HIST1H4F; TBPL1; HDAC9; GTF2B; SYK; TTC6; TP53

Protein Function

HDAC9 has several biochemical functions, for example, NAD-dependent histone deacetylase activity (H3-K14 specific), histone deacetylase activity, NOT histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HDAC9 itself. We selected most functions HDAC9 had, and list some proteins which have the same functions with HDAC9. You can find most of the proteins on our site.
Function
Related Protein
Function NAD-dependent histone deacetylase activity (H3-K14 specific)
Related Protein HDAC4; HDAC7A; HDAC7; HDAC2; HDAC11; HDAC3; HDAC1; HDAC5; HDAC10; HDAC9B
Function histone deacetylase activity
Related Protein HDAC11; HDAC5; HDAC1; HDAC9; ATXN3L; HDAC9B; HDAC10; SIRT1; HDAC4; NACC2
Function NOT histone deacetylase activity
Related Protein HDAC9
Function histone deacetylase binding
Related Protein KLF4; CDC20; NIPBL; ZNHIT1; HOXA10; ZNF703; YY1; NUDT21; SRF; ANKRA2
Function metal ion binding
Related Protein OVOL2; AMPD3; NDUFV1; ZFP652; PLA2G4AA; GNA12; KCNIP3B; ANTXR2A; RREB1; ZCCHC18
Function protein binding
Related Protein E2F3; Rhox5; SNRNP40; RALBP1; WNK1; KIAA1199; KIF5B; LRRC7; GIPC1; TRAPPC2L
Function protein deacetylase activity
Related Protein HDAC10; HDAC2; HDAC4; HDAC9; SIRT1; SIRT2; SIN3A; HDAC1; HDAC5; HDAC3
Function protein kinase C binding
Related Protein TRPV4; HSPB1; PKN1; ADD3; MARCKS; HDAC7A; PEA15A; DACT2; PICK1; AKT1
Function repressing transcription factor binding
Related Protein HDAC9; NFYB; TLE4; CTNNB1; HMGB1; HDAC7; HDAC5; HDAC1; MYC; RUNX2
Function transcription corepressor activity
Related Protein HOMEZ; TBL1XR1B; DRAP1; ENO1; KCTD1; MXD1; HOMEZB; HIF3A; DNMT3B; LOXL2
Function transcription factor binding
Related Protein MDFI; TNFRSF10A; GCM1; SNF8; LEF1; MAPK9; APBB3; SOX10; TFAP2A; HAND1

Interacting Protein

HDAC9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HDAC9 here. Most of them are supplied by our site. Hope this information will be useful for your research of HDAC9.
BCL6; USF1; NCOR1; ETV6; FOXP3; FOXP3; YWHAE; MEF2C; tkt1; WNK1; ZC3H11A; TOP1; TPR; RCC1; MKI67; NOP2; ADAR