HDAC9

  • Official Full Name

    histone deacetylase 9

  • Overview

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
  • Synonyms

    HDAC9; histone deacetylase 9; HD7; HDAC; HDAC7B; KIAA0744; MITR; histone deacetylase 7B; histone deacetylase 4/5-related protein; MEF-2 interacting transcription repressor (MITR) protein; HD9; HD7b; HDRP; HDAC7; HDAC9B; HDAC9FL; DKFZp779K1053;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect cell
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HDAC9-400H Active Recombinant Human Histone Deacetylase 9, GST-tagged Insect Cell GST
Human HDAC9-798H Recombinant Human HDAC9 Mammalian Cell His
Human HDAC9-1596H Recombinant Human Histone Deacetylase 9, His-tagged Sf9 Insect Cell GST
Human HDAC9-28444TH Recombinant Human HDAC9, His-tagged His
Human HDAC9-1372H Recombinant Human HDAC9 protein, His & T7-tagged E.coli His/T7 Pro23~Ala343 (Accession # Q9UKV0)
Human HDAC9-4652H Recombinant Human HDAC9 Protein, GST-tagged Wheat Germ GST
Human HDAC9-5601HCL Recombinant Human HDAC9 293 Cell Lysate HEK293 N/A
Human HDAC9-42H Recombinant Human HDAC9 Protein, His-tagged Insect Cell His
Human HDAC9-1303H Recombinant Human HDAC9 Protein (814-1011 aa), His-tagged E.coli His 814-1011 aa
Human HDAC9-3234H Recombinant Human HDAC9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HDAC9-301322H Recombinant Human HDAC9 protein, GST-tagged E.coli GST Gln477-Ile590
Human HDAC9-160H Recombinant Human HDAC9 Protein, His-tagged Insect cell His
Human HDAC9-3152H Recombinant Human HDAC9 protein, His-tagged E.coli His 335-440 aa
Human HDAC9-3100H-B Recombinant Human HDAC9 Protein Pre-coupled Magnetic Beads HEK293
Human HDAC9-3434HF Recombinant Full Length Human HDAC9 Protein, GST-tagged In Vitro Cell Free System GST 1069 amino acids
Human HDAC9-2912H Recombinant Human HDAC9 Protein (Gln628-Ser1005), N-His tagged E.coli N-His Gln628-Ser1005
Human HDAC9-3100H Recombinant Human HDAC9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HDAC9-2913H Recombinant Human HDAC9 Protein (628-1005), His tagged E.coli His 628-1005
Mouse Hdac9-3371M Recombinant Mouse Hdac9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Chicken HDAC9-2665C Recombinant Chicken HDAC9 Mammalian Cell His
Kit-1745 HDAC9 Fluorogenic Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • HDAC9 Related Signal Pathway

HDAC9 involved in several pathways and played different roles in them. We selected most pathways HDAC9 participated on our site, such as Alcoholism, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HDAC9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AlcoholismHIST1H3C;SHC2;DRD1A;H3F3B;HIST1H4M;DRD1;MAOA;HIST2H4;HIST1H2AN
Viral carcinogenesisMAPKAPK2;HIST1H4B;DLG1;GTF2A1;CDC42;HIST1H2BB;EGR3;HDAC1;HIST1H4D

HDAC9 has several biochemical functions, for example, NAD-dependent histone deacetylase activity (H3-K14 specific), histone deacetylase activity, NOT histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HDAC9 itself. We selected most functions HDAC9 had, and list some proteins which have the same functions with HDAC9. You can find most of the proteins on our site.

Function Related Protein
NAD-dependent histone deacetylase activity (H3-K14 specific)HDAC7;HDAC9B;HDAC3;HDAC11;HDAC7A;HDAC2;HDAC1;HDAC4;HDAC8
histone deacetylase activityNACC2;SIRT2;HDAC7;HDAC3;HDAC4;HDAC9B;HDAC2;HDAC11;HDAC5
NOT histone deacetylase activity
histone deacetylase bindingMEF2D;SKOR2;NR2E1;GLI3;KAT2A;PKN2;HDAC9;HDAC10;HDAC6
metal ion bindingDOM3Z;PRG4B;CALM4;NMRK2;AEBP2;MAP2K5;RXRAA;CYP46A1.2;OSGEPL1
protein bindingFAM46C;DYX1C1;FAM131B;SEMA7A;ESRP1;CNTNAP1;NR2F6;CORO1B;APOBEC3F
protein deacetylase activitySIRT2;HDAC10;SIN3A;HDAC5;HDAC1;HDAC4;HDAC9;SIRT1;HDAC2
protein kinase C bindingFLNA;SDC4;FEZ1;UGT1A7;PAWR;SDPR;DACT1;C1QBP;HDAC7
repressing transcription factor bindingHDAC7A;HDAC1;GMNN;RUNX2;TLE4;CTBP1;CTNNB1;PARK7;TBP
transcription corepressor activityMXI1;RYBP;ZMYND11;LMCD1;CCAR1;LHX9;SFMBT1;ELK3;MXD4
transcription factor bindingBCOR;NCOA2;KDM1A;GATA3;FOS;MAPK1;HHEX;MSX2;PPP1R13BB

HDAC9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HDAC9 here. Most of them are supplied by our site. Hope this information will be useful for your research of HDAC9.

BCL6; USF1; NCOR1; ETV6; FOXP3; FOXP3; YWHAE; MEF2C; tkt1; WNK1; ZC3H11A; TOP1; TPR; RCC1; MKI67; NOP2; ADAR

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