Recombinant Human HDAC9 Protein, GST-tagged

• Cat.No.: HDAC9-4652H
• Product Overview: Human HDAC9 full-length ORF ( NP_848512.1, 1 a.a. - 1069 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 144 kDa
• AA Sequence: MHSMISSVDVKSEVPVGLEPISPLD LRTDLRMMMPVVDPVVREKQLQQEL LLIQQQQQIQKQLLIAEFQKQHENL TRQHQAQLQEHIKLQQELLAIKQQQ ELLEKEQKLEQQRQEQEVERHRREQ QLPPLRGKDRGRERAVASTEVKQKL QEFLLSKSATKDTPTNGKNHSVSRH PKLWYTAAHHTSLDQSSPPLSGTSP SYKYTLPGAQDAKDDFPLRKTASEP NLKVRSRLKQKVAERRSSPLLRRKD GNVVTSFKKRMFEVTESSVSSSSPG SGPSSPNNGPTGSVTENETSVLPPT PHAEQMVSQQRILIHEDSMNLLSLY TSPSLPNITLGLPAVPSQLNASNSL KEKQKCETQTLRQGVPLPGQYGGSI PASSSHPHVTLEGKPPNSSHQALLQ HLLLKEQMRQQKLLVAGGVPLHPQS PLATKERISPGIRGTHKLPRHRPLN RTQSAPLPQSTLAQLVIQQQHQQFL EKQKQYQQQIHMNKLLSKSIEQLKQ PGSHLEEAEEELQGDQAMQEDRAPS SGNSTRSDSSACVDDTLGQVGAVKV KEEPVDSDEDAQIQEMESGEQAAFM QQPFLEPTHTRALSVRQAPLAAVGM DGLEKHRLVSRTHSSPAASVLPHPA MDRPLQPGSATGIAYDPLMLKHQCV CGNSTTHPEHAGRIQSIWSRLQETG LLNKCERIQGRKASLEEIQLVHSEH HSLLYGTNPLDGQKLDPRILLGDDS QKFFSSLPCGGLGVDSDTIWNELHS SGAARMAVGCVIELASKVASGELKN GFAVVRPPGHHAEESTAMGFCFFNS VAITAKYLRDQLNISKILIVDLDVH HGNGTQQAFYADPSILYISLHRYDE GNFFPGSGAPNEVGTGLGEGYNINI AWTGGLDPPMGDVEYLEAFRTIVKP VAKEFDPDMVLVSAGFDALEGHTPP LGGYKVTAKCFGHLTKQLMTLADGR VVLALEGGHDLTAICDASEACVNAL LGNELEPLAEDILHQSPNMNAVISL QKIIEIQSKYWKSVRMVAVPRGCAL AGAQLQEETETVSALASLTVDVEQP FAQEDSRTAGEPMEEEPAL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HDAC9 histone deacetylase 9 [ Homo sapiens ]
• Official Symbol: HDAC9
• Synonyms: HDAC9; histone deacetylase 9; HD7; HDAC; HDAC7B; KIAA0744; MITR; histone deacetylase 7B; histone deacetylase 4/5-related protein; MEF-2 interacting transcription repressor (MITR) protein; HD9; HD7b; HDRP; HDAC7; HDAC9B; HDAC9FL; DKFZp779K1053
• Gene ID: 9734
• mRNA Refseq: NM_001204144
• Protein Refseq: NP_001191073
• MIM: 606543
• UniProt ID: Q9UKV0