IL4I1

  • Official Full Name

    interleukin 4 induced 1

  • Background

    This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Synonyms

    IL4I1; interleukin 4 induced 1; LAO; FIG1; LAAO; L-amino-acid oxidase; Fig-1 protein; IL4-induced protein 1; interleukin four induced 1;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken IL4I1-3716C Recombinant Chicken IL4I1 Mammalian Cell His
    Human IL4I1-2320H Recombinant Human IL4I1 Protein, His-tagged E.coli N-His
    Human IL4I1-5225HCL Recombinant Human IL4I1 293 Cell Lysate HEK293 N/A
    Human IL4I1-654H Active Recombinant Human Interleukin 4 Induced 1, His-tagged CHO His
    Human IL4I1-1817H Recombinant Human IL4I1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human IL4I1-1178H-B Recombinant Human IL4I1 Protein Pre-coupled Magnetic Beads HEK293
    Human IL4I1-2613H Recombinant Human IL4I1 protein, His-tagged E.coli His
    Human IL4I1-01H Recombinant Human IL4I1 Protein, His-Tagged Insect Cell His
    Human IL4I1-1178H Recombinant Human IL4I1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse IL4I1-4518M-B Recombinant Mouse IL4I1 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Il4i1-653M Active Recombinant Mouse Interleukin 4 Induced 1, His-tagged CHO His
    Mouse IL4I1-4518M Recombinant Mouse IL4I1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Il4i1-639M Active Recombinant Mouse Il4i1 protein, His-tagged CHO His
    Mouse IL4I1-8173M Recombinant Mouse IL4I1 Protein Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • IL4I1 Related Articles

    IL4I1 involved in several pathways and played different roles in them. We selected most pathways IL4I1 participated on our site, such as Alanine, aspartate and glutamate metabolism, Cysteine and methionine metabolism, Valine, leucine and isoleucine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL4I1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alanine, aspartate and glutamate metabolismybaS;ALDH5A1;GAD1B;GPT2;GOT1;AGXTB;GLS2;GPT;GFPT1
    Cysteine and methionine metabolismMAT2AB;AGXT2;MAT2A;AHCY;CBS;SRM;LDHBB;LDHBA;SMS
    Valine, leucine and isoleucine degradationAOX2P;DLDH;HADHB;OXCT1B;ALDH3A2;HIBCH;HIBADHB;PCCA;ALDH1B1
    Tyrosine metabolismALDH3A1;GSTZ1;GOT2A;ADH2-2;COMTB;GOT2B;PNMT;ALDH3B1;FAH
    Phenylalanine metabolismHPDB;AOC2;ALDH3B1;HPDA;HPD;GM4952;PAH;ALDH3B2;AOC3
    Tryptophan metabolismALDH7A1;AOC1;RNF25;TDO2A;GCDH;HADHAB;MAOA;ABP1;CAT
    Phenylalanine, tyrosine and tryptophan biosynthesisPAH;GOT1;TAT;IL4I1;GOT2A;GOT2B;GOT2
    Metabolic pathwaysFUT9A;DHDPSL;PIGS;NAGLU;IL4I1;A4GALT;ALLC;ST6GALNAC6;UGT1A6B

    IL4I1 has several biochemical functions, for example, L-amino-acid oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL4I1 itself. We selected most functions IL4I1 had, and list some proteins which have the same functions with IL4I1. You can find most of the proteins on our site.

    Function Related Protein
    L-amino-acid oxidase activity

    IL4I1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL4I1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL4I1.

    Park, JH; Joo, CK; et al. Comparative Study of Tacrolimus and Bevacizumab on Corneal Neovascularization in Rabbits. CORNEA 34:449-455(2015).
    Lee, CH; Chang, JSM; et al. IL-1 beta Promotes Malignant Transformation and Tumor Aggressiveness in Oral Cancer. JOURNAL OF CELLULAR PHYSIOLOGY 230:875-884(2015).
    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    How to determine the dose of IL4I1 in clinical treatment? 12/12/2022

    The dose of IL4I1 in clinical treatment requires a number of preliminary studies, and is determined according to the type and severity of the patient's disease.

    What are the biological functions of IL4I1? 02/04/2022

    This is mainly involved in the regulation of immune response and anti-tumor effect, and has biological functions such as inhibiting T cell activation and proliferation, inducing macrophage M2 polarization, regulating T cell differentiation and apoptosis.

    What problems should be paid attention to when IL4I1 is used in preclinical animal test studies? 01/09/2022

    IL4I1 used in preclinical animal experimental studies needs to pay attention to its dose, administration route, administration time and other issues.

    Is there any side effect of IL4I1? 01/29/2021

    The application of IL4I1 may cause some side effects, such as fever, headache, fatigue, nausea, etc., but its toxic side effects are relatively small.

    What is the mechanism of IL4I1 in tumor therapy? 12/30/2020

    IL4I1 can inhibit the growth and spread of tumor cells, and at the same time activate immune cells in the body to enhance the body's immune monitoring ability to tumor, so as to achieve the effect of tumor treatment.

    How the purification technologies of IL4I1? 06/04/2019

    The purification technology of IL4I1 mainly includes affinity chromatography, ion exchange chromatography, gel filtration chromatography and so on.

    Customer Reviews (3)

    Write a review
    Reviews
    07/19/2022

      The protein was isolated by polyacrylamide gel electrophoresis, and the purity and protein composition of IL4I1 were determined according to molecular weight. -

      02/13/2021

        Molecular docking: The binding pattern of IL4I1 and its ligand is predicted by computational methods to obtain information about its structure and stability. -

        10/24/2020

          The thermal stability of IL4I1 was evaluated by heating the protein and observing its changes at different temperatures. -

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